HPAI-H5N1 virus infected ferrets showed a trend toward prolonged APTT on 3 dpi with a mean of 28 (17.1-38.9) seconds and on 4 dpi 26.3 (17.3-25.3) seconds, which was statistically significant when compared to all APTT results in pre inoculation samples (3 dpi p = 0.02, 4 dpi p = 0.02) .
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ORR was comparable between patients with standard and high-risk profile, the subgroups (25.8% versus 24.6%), while time-to-event endpoints showed a trend of shorter duration in high-risk patients, including median duration of response (5.6 months versus 8.3 months) and overall survival (9.3 versus 19.0 months).
But for potassium leves, participants on Tenofovir (TDF)-based therapy showed a trend of lower levels of biochemical parameters compared to those on Efavirenz (EFV) and Nevirapine (NVP)-based antiretroviral regimens.
Our results showed a trend toward these statements since a reduction in the abundance of taxa with oligotrophic characteristics, such as Verrucomicrobia [34] , and Planctomycetes [58] were detected in cultivated fertilized soils.
We found no significant association between cord blood 25(OH)-Vitamin D level and subsequent development of allergic sensitization or allergic rhinitis although the effect estimates showed a trend of decreased risk of allergic outcomes by deficient Vitamin D levels which has also been suggested by others [37] .
In situ hybridization data showed a trend: hsa-miR-21 levels were the lowest in normal tissue, and increasingly higher in adenocarcinoma and metastasis, meanwhile, a similar expression was observed in cancer cells nodes and liver recurrences, suggesting that hsa-miR-21 upregulation could predict an advanced metastatic disease.
The lenticular reduced glutathione also showed a trend toward normalization in these groups.
Several parameters, including lower gestational age, maximum temperature, low alkaline phosphatase, low serum bicarbonate and high Acute Physiology and Chronic Health Evaluation II showed a trend towards association with fetal mortality, but not reaching statistical significance.
In fact, 5 years after primary vaccination with 2- or 3-component aP vaccines, the children immunized with the 3-component vaccine showed a trend to a longer persistence of anti-PT IgG after the preschool boost compared with the recipients of the 2-component vaccine ( 18 ).
These probiotics resulted in significant improvement of infection or showed a trend in that direction.
Low admission phosphate showed a trend, but was not significantly associated with low iCa ( P = 0.052; Table 4 ).
In this study, including 83 intubated patients undergoing continuous subglottic secretion drainage (SSD), the authors found that patients with persistent intra-cuff pressures below 20 cm H 2 O showed a trend towards a higher risk of VAP (relative risk (RR) = 2.57, 95% CI = 0.78, 8.03), and a statistically significant risk of VAP among patients not receiving antibiotics (RR = 4.23, 95% CI = 1.12, 15.92).
We observed that tumors expressing TBX2 showed an increased tendency towards metastasis while CST6 expressing tumors showed a trend towards a decrease in metastatic potential.
Secondarily, we found that the children in the treatment group scored as needing significantly less caregiver assistance during self-care and social activities and showed a trend toward higher skills in these areas.
Recently, increased β-galactosidase (EC = 3.2.1.23) and cathepsin E (EC = 3.4.23.34) activities and a reduced α-fucosidase (EC = 3.2.1.51) activity have been found in the CSF of PD patients compared to healthy controls, and β-glucocerebrosidase showed a trend toward reduction in the PD group (17).
Additionally, IUGR group showed a trend towards an augment in plasma TG, TC and hepatic TC concentration at E20, and a significant increase at PW40 ( p <0.05) (Fig. 1 C–E).
( 22 ) The SL group showed a trend towards higher LPCAT3 and LPIAT1 mRNA expression as well as liver X receptor (LXR) α compared with the other groups (Fig. 6 A).
Interestingly, their study showed that there was no effect of fructose intake in the subjects with a BMI between 25 and 29 kg/m 2 , although serum uric acid showed a trend to be elevated depending on body-weight status.
Conclusion Although the changes in biological rhythm were not statistically significant during the time period evaluated in this study, it is noteworthy that the trajectory of the score showed a trend towards improvement, which may indicate a positive impact on treatment, though it may take a longer time than expected.
Mice sub chronically exposed to cigarette smoke showed a trend towards hyperresponsiveness to methacholine in our experiments, an effect that was also observed in other studies in smoke exposed mice [26] and guinea pigs [27] .
The evaluation by IVUS in this study, as in the CARE II 16 showed a trend to stent expansion over time, more markedly in the group with drug-eluting stents, a finding that motivates further research.
IL-1β and CXCL3/KC showed a trend towards an increase in WT mice following BLM administration, but there were no statistically significant differences between any of the groups studies (Figure 4 B and C, n = 5).
Comparison with historical data showed a trend towards superior efficacy of nilotinib versus imatinib.
We observed that IFN γ (Log-rank trend p = 0.023), L1 (Log-rank p = 0.027), antigen processing and presentation (Log-rank p = 0.145), and apoptosis (Log-rank trend p = 0.034) pathways significantly correlated or showed a trend to correlate with prognosis of TNBC patients, where higher expression of these pathways went hand-in-hand with a favorable 5-year metastasis-free survival ( Fig. 5 ).
study showed a trend toward higher dosage when compared to the other genotypes, which might have resulted in more severe side effects (Maitland-Van Der Zee et al., 2003 ).