Comparing the pre-surgery and post-surgery data, VEGF and IGF-1 of both groups showed a trend of decrease, but no statistically significant difference was observed.
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Indeed, p.Glu122Lys CNNM2 membrane expression was significantly reduced compared with wild-type CNNM2 (66% decrease, P <0.05) and p.Ser269Trp CNNM2 showed a trend towards reduction (46% decrease, Figure 3B ).
In addition, participants who consumed the soy-based meal replacement product showed a trend for greater weight loss and improvement in HRQOL.
In this study, boys showed a trend for stronger right-hemisphere lateralization for visuospatial memory than girls, but there was no gender effect on language laterality.
Individual treatments with Ragaglitazar and Pioglitazone showed a trend towards reducing BP, but it was not statistically significant.
The different chaperone proteins responded differently to the ICU condition: HSP70 was significantly increased (p<0.01) in the 5–8 day group ( Figure 4G ), αB-crystallin showed a trend towards an early and maintained elevated level, albeit not statistically significant (p = 0.06) ( Figure 3H ), and HSP90 protein levels were not affected by the ICU condition ( Figure 4I ).
The AP group showed a trend for higher levels of baseline systolic blood pressure than the control group.
The contents of tectoridin and baicalin had no significant difference compared with the control group while they showed a trend of increase under high-intensity enhanced UV-B radiation.
ET cases showed a trend toward a reduction in cMpl expression (0.05±0.04) compared to healthy controls although without statistical significance ( Figure 2 ).
In addition, the extreme myopia group showed a trend toward lower social functioning.
Similar analysis showed a trend positive relationship between changes in GNAS and changes in BMI.
In contrast, the combination of LDLr −/− and a cholesterol-rich diet only showed a trend towards an increased total size of enthesophytes compared to WT mice on a normal diet; however, values did not reach significance (Figure 4 B and C).
Eleven genes ( CXCL13 , EXOC7 , HAPLN1 , RFX7 , RPS28//FLJ46061 , SSX3 , ZNF3 , ABO , CLIC5 , PRRG3 and RGS4 ) showed a trend for association with DMFS by multivariate Cox modeling within the training cohort.
Patients treated with CoQ10 showed a trend toward slowing the decline in total functional capacity decline over 30 months, as well as beneficial trends in some secondary measures [ 32 ].
Tumors showed a trend toward increased Fgf15 expression.
A subanalysis of a total of only 25 children with lupus nephritis who were enrolled in a large randomized clinical trial of mycophenolate mofetil (target dose 3.0 g/ day) versus cyclophosphamide (0.5 to 1.0 g/m 2 /month) [ 72 ] showed a trend towards better renal response to 24-week induction therapy with mycophenolate mofetil than with cyclophosphamide (7/10 (70%) vs. 8/15 (53%)) [ 73 ].
Concentrations of MitoG above 10 μM slightly decreased the OCR owing to ATP synthesis, and lower concentrations in the range 2–5 μM showed a trend toward an increased OCR due to proton leak and a decreased respiratory reserve capacity.
The SNPs rs2380205 (10p15.1, intergenic, 2.6 kb 5′ to GDI2 ) and rs1045485 (2q33.1, CASP8 p.Asp302His) showed a trend towards association, and the SNPs rs2284378 (20q11, RALY c.-93 + 6158 T > C) [ 63 ] and rs1982073 (19q13.2, TGFB1 p.Pro10Leu) [ 23 , 24 , 44 ] were not tested on the iCOGS array.
Both GRP75/Mortalin and Calreticulin showed a trend towards increased levels in the small cohort of SMA patients compared to controls (Figure 3 ).
Although this trend is consistent with the data shown in Figure 4 , their data also showed a trend of lower Lyp2 in patients with RA.
Furthermore, cytokine analysis showed a trend toward increased serum Th17/Th1 ratios when P. gingivalis infection was present in mice receiving either CFA/CII or IFA/CII immunizations.
At later time points, both daf-18 mutant animals showed a trend downward in response to GSH treatment although it was not significant ( Fig. 6 ).
Phospho (p)-c-Jun also showed a trend of decreased phosphorylation.
Results obtained with the same technique in standard infertility programme showed a trend towards lower overall clinical outcomes from vitrified oocytes, especially over the age of 34 [ 74 – 76 ].
Our results showed a trend for higher total cholesterol and LDL-cholesterol in ε 4 carriers than in ε 3-homozygotes carrier psoriasis patients.