Surprisingly, during this time period, the MG density of the lip (r) in the LMC dropped significantly, and the lip (r) in the RMC showed a trend of decreasing MG density (see Fig. 4 ).
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In summary, at 15 mo of age, morphometric analysis showed a trend toward hypertrophy and a significant increase in fibrotic lesions in the hearts of BACHD mice.
Patients with CRP level >6 mg/L showed a trend for increased DKK-1 level, but mean DKK-1 level was still higher for patients with normal than increased CRP level (28.7 ± 13.9 vs 26.5 ± 11.7 pmol/L; P trend = 0.06) ( Fig. 3 ).
The female subjects also showed a trend towards increased fat percentage and decreased SMM with aging.
We found that both HIRZ and ROA showed a trend towards down regulation in crowding but this trend was not significant (HIRZ P = 0.513; ROA P = 0.465) ( Fig. 2 ).
Here, we demonstrated for the first time that the differentiation potential of MSCs was preserved even after exposure to high doses of cisplatin, and we did not find a general dose-dependent reduction of the differentiation capabilities: While the adipogenic differentiation was found to be reduced at least after treatment with high doses of cisplatin, MSCs showed a trend towards increased osteogenic differentiation after cisplatin treatment.
The factors that were significantly related to survival or showed a trend toward being significantly related to survival were included in a multivariate logistic-regression model.
In conclusion, preliminary data of this small study in a Morquio A population with relatively good endurance confirmed the acceptable safety profile of elosulfase alfa and showed a trend of increased exercise capacity and muscle strength and decreased pain. © 2015 The Authors.
2B ) revealed a similar spatio-temporal exploration among groups, but DEDTC-treated groups showed a trend to decrease the swimming at the upper half of the apparatus.
Moreover, healthy volunteers in IH condition simulating moderate OSA showed a trend of decreased insulin sensitivity and glucose effectiveness after five hours [ 6 ].
Staining of ICAM1 in tumors from these patients showed a trend towards higher expression of ICAM1 in patients who did benefit from ipilimumab, however these results were not statistically significant, probably due to the small sample size.
Results Macroscopic examination The hardness score of the PLCL/Fg mesh and PPM remained between 3 and 4, although the PPM showed a trend of slight increase in hardness as the study progressed to 24 weeks ( Figure 1A ).
Overall the estuary and harbor samples showed a trend of increasing urban signature percentage with increasing rainfall intensity, and a slight decrease with distance from urban sources, as would be expected by dilution.
mCa1 occurred in 38% of total patches and compared to WT showed a trend towards an increase in the probability of occurrence (ratio of active to total patches) in the UCP2 -/- group, however, without reaching statistical significance ( P = 0 . 08 , calculated by Chi-square test).
Tumor rate constant of [ 11 C]erlotinib influx, i.e., K1, showed a trend towards positive correlation with TBF(E−) and TBF(E+); however, this was not statistically significant ( r s = 0.714, P = 0.058 and r s = 0.405, P = 0.327, respectively, see Fig. 3c ) (see Additional file 1 : Table S4 for detailed results).
Sensitivity analysis for unobserved confounding The difference-in-difference analysis showed a trend towards more emergency admissions among intervention patients than controls, but the effect size was smaller than in the primary analysis and did not reach statistical significance (difference 0.10 admissions per head, 95% CI −0.06 to 0.26, p=0.220) (see online supplementary table S1 and figures S1 and S2).
Our study using hourly temperature data in a large international study population corroborates the findings of a Taiwanese study with known hourly temperature data at ICH onset which showed a trend of increased ICH occurrence towards the lower temperature and is also consistent with prior investigations and clinical observation of a peak ICH occurrence in the winter due in part to the trigger effect of low ambient temperature on the risk of ICH onset at particular times of the day [ 2 – 5 , 25 ].
Furthermore, miR-26a and miR-29b showed a trend towards progressively reduced expression over time.
Ex vivo IFN-γ ELISpot responses to PPD 2 weeks after challenge showed a trend toward an inverse correlation between the number of BCG detected in the skin biopsy specimens by qPCR and the number of CFU, consistent with our previous findings with this model [ 10 ].
Importantly, data of the 320 mg group showed a trend of superior anti-HIV activity to that of the 160 mg group.
The modulation of TFAM expression, TFAM-binding to mtDNA and mtDNA content with aging and CR showed a trend shared by the skeletal muscle and liver, but not by the frontal cortex counterpart.
Expression of Tgfb1 , a pro-fibrotic growth factor, showed a trend of increasing in the IU+ group, whereas mRNA for Il6 , a cytokine implicated in NAFLD, showed a trend of increasing in the IU group.
Phenotypic primitive cells were increased in 126OE groups for seven of nine samples ( Figure 4 A) with concomitant reduction of differentiated cells; four of nine samples showed a significant reduction for CD15 + cells ( Figure 4 B), and six of nine showed a trend for reduced CD14 + blasts ( Figure S4 E). 126OE caused an increase in CD15 + blasts for two samples ( Figure 4 B).
3b ) leachates showed a trend to decrease through time, and fluctuated before reaching a stable concentration in oak leachates (Fig. 3d ).
The results of the study showed a trend towards cognitive impairment in the control group and an opposite tendency of mice treated with Aβ1-6 A2V TAT(D), whose cognitive performances were no worse than at the beginning of the treatment with Aβ1-6 A2V TAT(D).