Moreover, the comparison between the WT and Homozygous groups also showed a trend in the differential abundance of Cyanobacteria ( P = 0.05, RA: 0.48 %, LFC=0.75), Verrocumicrobiota ( P = 0.06, RA: 0.05 %, LFC=1.3) and Firmicutes ( P = 0.06, RA: 41 %, LFC=0.5).
Conversely, the relative contents of sweet amino acids showed a trend of decreasing and then increasing ( p < 0.05).
In the reduced model, TMT-1 showed a trend toward significance ( p = 0.050, OR = 0.60, 95% CI: 0.36 to 1.00), suggesting that better visual perception reduced the odds of injury by approximately 40%.
Supplementation with HMB also showed a trend towards longer survival time, with subcutaneous TB group doubling survival time to 28 days ( p < 0.05), while the intraperitoneal TB group showed a 42% increase (NS), possibly indicating that HMB needs time to effect a change [ 85 ].
Metformin-treated mice showed a trend to spend less time in annulus 40 area as compared to the controls, which reached significance for session 5 ( Figure 4A , p <0.05).
Notably, the thermal hypersensitivity showed a trend to recover over weeks 2 to 4 (slope: 0.21 ± 0.02, t-value: 7.94, p < 0.05); see also the changes expressed as the MPE ( Figure S4A in Supplementary Materials ).
In our feasibility study in a single-arm design (n = 7), a 6-week Qigong exercise program demonstrated an improvement in sleep quality measured by Parkinson’s Disease Sleep Scale-2 (PDSS-2), in which the results showed sub-scores of PDSS-2 were significantly improved or showed a trend of improvement including motor symptoms at night ( p < 0.05) and disturbed sleep ( p = 0.06) in individuals with PD [ 17 ].
Weight measurements showed a steady increase in both groups throughout the study, with no significant differences observed at any point, but the DNC group showed a trend of faster weight gain ( p > 0.05) ( Figure 1 D). 3.2.
Histological analysis of activated Caspase 3, a marker of early apoptosis, indicated no significant changes in sub‐endocardial apoptosis (Figure S2 A and C), although the apoptotic effect of DS‐induced hypertension showed a trend ( P = .05; Table S9 ).
Transcriptomic analysis showed that 48 steroidogenesis pathway genes in the livers of HC mice exhibited significant expression changes ( p < 0.05), and 42 of these genes showed a trend of reversal after GP treatment, with 32 genes being significantly reversed ( p < 0.05).
Weight-for-age z scores also showed a trend towards statistical significance, changing from −0.86 to −0.65 ( p = 0.05).
The risk C-allele in the rs2943641 polymorphism, near the insulin receptor substrate 1 gene ( IRS1 ), showed a trend towards association with increased HOMA-IR (beta = 0.36, SE 0.18, p = 0.050), and the T-allele of the rs4607103 polymorphism, near the ADAM metallopeptidase with thrombospondin type 1 motif 9 gene ( ADAMTS9 ), was associated with postpartum diabetes (OR = 2.12, SE 0.22, p = 0.00055).
However, RV-GLS was significantly lower in the ID group ( p = 0.005), while TAPSE and pulmonary acceleration time showed a trend towards lower values in the ID group ( p = 0.05 for both).
Adenine intake decreased the diversity and separated microbiota structure Chao1, Observed_species, and Shannon indexes were significantly lower in the NMM group compared with the NC group ( P < 0.05; P < 0.05; P < 0.05), and the above indexes showed a trend of reduction in the NML group ( P > 0.05; P > 0.05; P > 0.05) ( Fig. 4 A–C), suggesting that 50 mg/(kg·d) adenine intake markedly reduced diversity of gut content microbiota of mice.
Physical examination of patients revealed crackles in 8.2% (n = 82) and showed a trend of its presence in patients with persistent post-COVID-19 symptoms (9.9% vs. 5.8%, p = 0.05).
Conditioning showed a trend for an effect on cognitive function at P22 in all tests ( p < 0.05, Fig. 3 a–c) and a significant effect at P29 in test 2 ( p < 0.004, Bonferroni correction, Fig. 3 e).
Fatty atrophy of the infraspinatus tendon showed a trend toward progression at latest follow ( P = .05), but not in the supraspinatus ( P = .075).
The baseline cGP/IGF‐1 ratio showed a trend toward a positive correlation with FM‐UL scores of day 90 ( B = 2.33, 95%CI = −0.07─4.73; P = 0.05; n = 27), but not with the mRS.
With the increase of calcium concentration, soil contents of TC, TN, TP, AK, C:N, C:P, and N:P showed no significant differences ( p >0.05), while soil water-soluble calcium and exchangeable calcium exhibited significant differences and showed a trend of gradually increasing content ( p <0.05).
IVD height decreased with age, showed a trend toward significantly decreasing with spinal level ( p = 0.05), and showed no significant interaction between age and level (Figure S6C ).
6 variants, 1 located in the signal peptide (p.M1I), and 5 non-synonymous variants (p.A36T, p.Y57C, p.W69R, p.R101Q, p.I169T) showed a trend towards reduced responses to IL-10 stimulation, but these differences did not reach statistical significance of p < 0.05 in the HEK293 cell system (Fig. 2A ; Supplementary Fig. 3A ).
In this study, in the LD, the relative mRNA levels of the FAS and H-FABP genes showed a trend toward 4-year-old>2-year-old >3-year-old (p<0.05), while PPARγ expression was highest at 2-year-old (p<0.05).
In the OF test, AP2γ KO mice showed a trend toward a decrease in the distance traveled in the anxiogenic center of the arena ( P = 0.05, Figure 4B ), with no changes in locomotor activity as denoted by similar average velocity ( Figure 4—figure supplement 1A ).
In CPP patients, FC between the right lateral hypothalamus and right SFG showed a trend-level correlation with peak LH levels (r=0.362, P =0.050).
But shrub‐layer BGB had a significantly positive relationship with mean annual precipitation ( p < .05), while grass‐layer BGB showed a trend of decrease with increasing mean annual temperature ( p < .05).