Barely Significant
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“showed a trend”

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In the literature

Four studies found no significant difference in serum or plasma serine levels between children and adults with or without autistic disorder, PDD-NOS, Asperger's Syndrome or autism spectrum disorders (mixed sample) [ 60 , 69 , 70 , 75 ], one study showed a trend towards a decrease in children with autistic disorder [ 60 ] and another reported significantly increased plasma serine in children with autism spectrum disorders [ 87 ] and significantly lower levels of serine were reported for platelet poor plasma in autism spectrum disorders [ 86 ].
However, while mice on a normal diet showed a trend for a negative gene dose-dependent effect on fasting blood glucose, glucose tolerance and cholesterol (with Dp11(1)/+ mice showing a significant reduction in fasting blood glucose, when compared to WT animals; Fig 7B ), high-fat diet treated animals showed a significant negative gene dose-dependent effect on glucose tolerance and cholesterol (glucose tolerance: F [2,65] = 3.196, p = 0.04; cholesterol: F [2,79] = 3.9, p = 0.02; Fig 7C and D and Fig S3 of Supporting Information).