“showed a trend”

However, the injection of UCB CD34 + cell-derived CD161 − ILC1s showed a trend towards better prolongation of survival than the injection of UCB CD34 + cell-derived NK cells in our LSC model (Fig. 6j, k ).

The experimental results indicate that the BOD5 value showed a trend of first decreasing and then increasing during the treatment process, reaching its lowest point at 60 min.

MBP immunoreactivity showed a trend toward increased staining signal in ARTE10 mice compared to WT controls.

In the hyperthermia group, driven by intratumoral injection of Ac-HSA-PLGA-AuNCs, tumor ablation was observed; however, the growth of the remaining tumor tissue was unaffected and showed a trend comparable to that of the unheated Ac-HSA-PLGA-AuNCs groups.

We identified several other phage proteins that co-occurred with this ssDNA binding protein, which showed a trend towards association with the generalist phenotype and suggest additional possible members of this pathway (Supplemental Table S2).

1.81 ± 0.25, P = 0.0064); IL-6, IL-8, and MCP-1 showed a trend in reduction, although they did not reach the conventional statistical significance level (Fig. 6 ).

Exploratory outcomes, assessed by univariate analyses, suggested that only elevated LDH levels showed a trend towards worse PFS (HR: 2.0; 95% CI 0.92‒4.3; P value: 0.08), while high LDH levels (HR: 4.1; 95% CI 1.3‒13.2; P value: 0.02) and the number of extra nodal sites more than 1 (HR: 4.0; 95% CI 1.4‒11.6; P value: 0.01) were significantly associated with worse OS (Additional File 1: Table S1).

Similarly, greater percentage of total weight loss (%TWL) showed a trend toward lower anxiety scores but did not reach statistical significance (β = −0.06, p=0.07).

Individual M2-like genes such as MRC2 15 showed a trend for decreased expression after RO7119929 treatment, while others, such as TREM2, 16 did not change consistently across patients, or even showed a slight overall increase on treatment, as exemplified by CD163, which may describe a subpopulation of M2-like TAMs 17 ( figure 5C , right).

This stability is reflected in the improved functional outcomes: the BF group supported a genus-level enrichment of beneficial taxa like Succinivibrio (a propionate producer within the Bacteroidetes phylum) and showed a trend toward higher Prevotella abundance, while simultaneously suppressing Methanobrevibacter .

According to the results of the NEURO-BREAC trial, a lower Karnofsky performance score of 70–80, a history of hypertension, and beta blocker treatment were significantly associated with moderate-to-severe CIPN, and a BMI of ≥30.0 kg/m 2 showed a trend.

Kaplan–Meier analysis showed a trend toward reduced overall survival in patients with high CHPT1 expression compared with those with low expression ( Figure 6 B).

However, patients who demonstrated an increase in ctDNA levels between baseline and surgery showed a trend toward lower 5-year disease-free survival (HR 3.66).

sutchuenense mainly showed a trend of westward contraction and eastward expansion. 3.5.

In contrast, the GFAP levels showed a trend toward increased expression, which may reflect reactive astrogliosis [ 49 ].

In the present study, patients with rTLE showed a trend toward lower values of sympathetic modulation in the interictal state.

Consistent with this, mass spectrometry showed a trend toward increased NRF1 protein abundance following NanA (log 2 FC = +1.55; padj = 0.135; Table S7 ).

8 From 2000 to 2014, national indicators, as hospitalization for exacerbation and mortality, showed a trend toward an increasing burden of COPD among women thus approaching that of men. 9 Furthermore, daily smoking prevalence in metropolitan France has largely declined since the last decades, particularly among men, 9 however its current prevalence remains significant.

Third, while LIFUS2 yielded significant behavioral effects and showed a trend toward gut microbiota changes, the precise neurobiological mechanisms underlying these effects are not yet fully understood and require further study.

Serum levels of IL-6 showed a trend toward increasing with the deterioration of kidney function 24 .

While AshwaSR 300 mg showed significant reduction on day 60 from baseline, the AshwaSR 150 mg group also showed a trend of decreasing cortisol levels over the study duration.

circRMST showed a trend of higher abundance in SCLC-A compared to SCLC-N and SCLC-P ( Figure 1G ).

Although the meta-analysis showed a trend of improvement in some cognitive indicators (such as MoCA), these findings should be interpreted with caution.

Discussion In our study, in the daratumumab-treated cohort, patients with 1q gain or amplification showed a trend towards a shorter PFS and patients with 1q amplification presented with a shorter OS, consistent with the concept that amplification reflects a more advanced cytogenetic event.

7 Interestingly, the more distal outcome, renal failure, showed a trend toward a lower hazard (HR 0.91, 95% CI 0.70–1.17), although both confidence intervals were wide and included the null. 4.1 Potential mechanisms The observed benefits likely stem from the complementary mechanisms of both drug classes.