While BAC-dosed mice showed a trend toward greater monocyte, neutrophil, and epithelial cell counts at 4 h after instillation, BAC does not cause a significant increase in any of these cell types at either time point.
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Although men showed a trend toward requiring more blood transfusions, the difference was not statistically significant (proportion of females needing transfusions: 89/246 = 36%; proportion of males needing transfusions: 47/106 = 44%; RR for women: 0.82, 95% CI [0.62, 1.06]).
In our study epinephrine stimulation ex vivo showed a trend to suppress IL-6 expression and release from PBMCs.
GDF15 showed a trend for elevation in complicated children 257 ± 225 pg/ml vs. 114 ± 66 pg/ml in the non-complicated; however, it didn’t reach statistical significance ( P = 0.149) (Table 2 ).
Although total survival time and post-onset survival duration were not significantly prolonged by MSC-sEV treatment, MSC-sEV treatment significantly delayed progression from a mild symptom phase (NeuroScore 1) to more severe symptoms (NeuroScore 2) compared with vehicle-treated controls and showed a trend toward slower weight loss.
YIAD-0501 showed a trend toward reduced oligomer formation and dissociation of pre-formed Aβ(pE3–42) oligomers (Fig. 2 C, Fig.
In this unadjusted analysis, no statistically significant difference in post-operative survival was detected between the two centres ( p = 0.065), although GS patients showed a trend towards longer postoperative survival, particularly within the first two years after surgery.
Additionally, PDK1 and PDK4 expression showed a trend toward correlation with aortic succinate levels, suggesting an association with macrophage-driven inflammation.
Also, at high temperature, individuals reared on a high-carbohydrate diet showed a trend toward better survival than those reared on a regular diet, but the difference is not statistically significant (Fig. 3 A, Table S6 ).
Swallowing dysfunction showed a trend toward higher malnutrition risk (RRR = 4.07), though this did not reach statistical significance ( p = 0.070).
35 They found that, compared with NIVO+RELA, NIVO+IPI had similar PFS and ORR, while BRAF/MEK inhibitors had similar PFS and significantly higher ORR; NIVO+RELA also showed a trend of fewer grade ≥3 AEs than NIVO+IPI.
However, patients with a high number and density of distal TLSs showed a trend toward better survival than those with a low number and density of distal TLS; however, this difference was not statistically significant.
Moreover, TNBC patients with low PKM expression showed a trend towards benefitting from radiotherapy not quite reaching significance, while there is no difference in response to radiotherapy in TNBC patients with a high expression of PKM (Fig. 2 H).
In survival analyses, higher CXCL11 expression was associated with worse distant metastasis-free survival and showed a trend toward poorer overall survival, whereas higher KLF2 expression was associated with better outcomes.
Fbln5 Deficiency Compromises ECM Integrity at the Epidermal–Dermal Junction in Aging Skin Among the ECM proteins at the epidermal–dermal junction (Fujiwara 2024 ), the RNA‐seq data showed a trend of decreased expression for integrins, collagens, and laminins in the 12‐month‐old Fbln5 KO mice (Figure 3A,B ; Table S5 ).
Conversely, levels of the crotonylation erasing enzyme chromodomain Y‐like (CDYL) showed a trend of decreasing within 2 to 4 days postactivation but rebounding by day 7, coinciding with HIV latency reestablishment ( Fig. 1A ).
IL‐2 supplementation showed a trend toward a higher proportion of cells expressing 2 or >3 markers, however this was not significant (Figure 5A,B ).
2C ), age and Pb showed a trend to identify individuals with increased carotid IMT.
In addition, transgenics showed a trend toward a reduced chronotropic response following bolus administration of the β-adrenergic agonist isoproterenol compared with WT controls ( Fig. 4 C).
19 In the CRS group, liver weight showed a trend of reduction in comparison to the CON group, but there was no significant difference between the two groups ( Figure 1 G).
During stage N2, SDNN, Poincaré long-axis standard deviation and detrended fluctuation analysis alpha-1 were elevated, approximate entropy was reduced, and very-low-frequency (VLF) power was increased; the low-frequency/high-frequency (LF/HF) ratio showed a trend toward elevation.
Compared with age-matched children without CPP, GnRH therapy showed a trend toward longer PFS, though not statistically significant ( p = 0.10).
While patients with SpA showed a trend toward better outcomes compared to RA and PsA, our analysis suggests this may be partly mediated by younger age and specific engagement patterns rather than diagnosis alone.
While [ 177 Lu]Lu-FAP-2286 alone was sufficient to significantly inhibit tumor growth, the combination regimen showed a trend toward improved tumor growth control under the experimental conditions evaluated.
Meanwhile, while the numbers of defective HIV DNA (3′ deletions/hypermutations and 5′ deletions) detected with the IPDA showed a trend of a decrease over time in the 2 groups with total HIV DNA decrease, they remained stable or even increased in the 2 groups with an increase in total HIV DNA ( Figure 2 B ).