“showed a trend”

Starvation led to progressive body weight loss in both groups, and Trim24 −/− mice showed a trend toward more rapid weight reduction over time, although this difference did not reach statistical significance under the conditions tested ( Figure S4B ).

CLDN6 expression showed a trend toward shorter PFS but did not reach statistical significance ( p = 0.096).

Cluster heatmaps ( Figure 7 F) and species composition analyses ( Figure 7 G) supported these observations: compared to the Mod group, the SI-treated group showed a trend toward decreased abundance of potentially harmful genera (e.g., Mucispirillum, a genus associated with chronic inflammation [ 44 ]) and increased abundance of beneficial taxa, including short-chain fatty acid (SCFA)-producing Akkermansia [ 45 ].

The sildenafil-treated group showed a trend toward lower HIF-1α immunoreactivity compared to the contrast media group, with a medium effect size (Cohen’s d = 0.71), though this difference did not reach statistical significance after correction for multiple comparisons (Dunn’s test, p = 0.050).

Volatile acidity (expressed as acetic acid) showed a trend of first decreasing and then increasing, reaching its highest value (0.53 g/L) at 5 days and its lowest value (0.38 g/L) at 9 days.

In our study, ANGPT1 expression showed a trend toward higher levels in infertile patients, while ANGPT2 was relatively higher in donors.

Fibrosis-related variables, including elastography-defined fibrosis stage ≥ F2 and higher FIB-4 categories, showed a trend toward discordance; however, these associations did not reach statistical significance ( p = 0.055 and p = 0.09, respectively) ( Table 3 ).

In contrast, patients with PE exhibited significantly higher methylation levels in T compared with D tissues ( p = 0.035), while A tissues showed a trend toward higher methylation compared with D tissues, although this difference did not reach statistical significance ( p = 0.052).

Although no significant association was found between the response criteria and progression ( p > 0.05), functional imaging showed a trend toward better correlation with longer progression-free survival.

Although droplet size increased slightly after 30 d, it still showed a trend of first increasing and then decreasing with the concentration of XG.

Taken together, STEMI patients showed a trend toward lower FGF23 levels 3 h after reperfusion, consistent with the decline phase observed in the TASH cohort at the 2–4 h window. 4.

The two groups showed similar reductions in negative emotional experience during emotion regulation, whereas individuals with habitual exercise showed a trend toward lower right dorsolateral prefrontal cortex (rDLPFC) activation during expressive suppression.

Analysis of microglial polarization markers revealed that the M1-associated protein CD14 showed a trend toward an increase in I S without reaching statistical significance, whereas the M2 marker Arg1 was reduced.

While VEN treatment significantly reduced, or showed a trend toward reducing, the colony number and size of PAR cells, both the VENM and VENK cells showed minimal changes in colony number and size, indicating reduced sensitivity ( Figure 1 E,F).

For instance, patients on an SERD (fulvestrant) showed a higher hazard ratio (HR = 2.302, p = 0.0678), and those with non-visceral metastases (HR = 2.008, p = 0.0696) also showed a trend toward poorer outcomes without statistical significance. 3.4.

Although the four groups were comparable in terms of age, the sex distribution showed a trend-level difference between the ADHD and ED groups, which did not survive correction for multiple comparisons.

iTRPC6GoF showed a trend towards an increase in Ca 2+ influx in comparison to TRPC6-WT but with very large variability.

The drug release of drug-carrying GPDD micelles showed a trend of being rapid first and then slow release, which was greatly affected by pH.

Median overall survival showed a trend toward improvement at 23.3 months versus 18.9 months, although this difference did not achieve statistical significance in the primary analysis [ 20 , 117 ].

Furthermore, the CBNF composite showed a trend of gradually increasing IFSS with higher loading, reaching the maximum value of approximately 8.5 MPa at 30 wt%. 3.5.

Indeed, extent of nodal involvement at first BC diagnosis was significantly associated with worse DRFI (patients with N3 tumors presented a significantly worse DRFI post-ILRR as compared with those with node-negative disease: HR 5.48, 95% CI 1.16-25.95; P = .032), and patients with larger tumors at first diagnosis showed a trend towards worse DRFI post-ILRR, although not statistically significant (pT4 versus pT1: HR 7.62, 95% CI 0.94-62.02; P = .058) ( Table 3 ).

Surgery performed within 6 weeks of neoadjuvant therapy was significantly associated with longer OS, while DFS and PFS also showed a trend toward improvement.

Although moderate and severe myopia showed a trend toward greater residual myopia compared with mild myopia, these associations did not reach statistical significance.

Consistently, Tregs showed a trend toward higher abundance in tumor tissues compared to adjacent healthy tissues ( Figure 4D ).

The use of SGLT2is in 9 SLE patients with DM [ 6 ], CKD [ 7 ], and cardiac disease [ 3 ] showed a trend of reduction in proteinuria, stable kidney function over-time, and without adverse cardiovascular events despite a high-risk population.