Furthermore, diacerein showed a trend toward reduced aortic atherogenic plaques and attenuated the inflammatory response in the heart and adipose tissue in ApoE knockout mice, suggesting potential anti-atherosclerotic effects.
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Although FMT showed a trend toward improved ALT and TC levels, these changes were not statistically significant.
In contrast, BMs showed a trend of enrichment proliferating CD8+ T cells (CD8_Cycling).
The proportion of pixels with a low ventilation-to-perfusion impedance ratio showed a trend toward increase in dorsal lung regions in patients with metabolic syndrome (4.25%, 95% credible interval: − 4.49 to 13.1, posterior probability = 80.3%).
Notably, granzyme A expression showed a trend toward upregulation, as shown in Fig. 6G (blood) and Fig. 6J (spleen), suggesting that, in the presence of IFN-γ, IRF2-deficient NK cells may retain some cytotoxic potential despite their immature status.
The contractile gene set showed a trend of being lower compared to control VSMCs, whereas phenotypic switching gene set showed the opposite trend (Fig.
Regarding their assessment of the potential advantages and disadvantages of GT, our analysis showed a trend that people who would reject GT at the current time tended to rate the potential disadvantages higher and the benefits lower than those who would consider GT ( Figures 6 and 7 ).
36 In fact, leukemic transformation was significantly associated with NRAS (HR, 1.64) and PTPN11 (HR, 2.11) mutations, while KRAS showed a trend in the same direction (HR, 1.41).
pylori -positive patients had a significantly longer PFS and showed a trend toward improved OS with ICI therapy 105 .
However, the efficacy of TMB-guided monoclonal antibodies is limited, because nivolumab monotherapy showed a trend toward improved outcomes in patients with TMB-H, whereas no significant benefit was observed in patients with TMB-L.
However, an alternative dietary index (AHEI-2010) showed a trend toward reduced colorectal cancer mortality.
Intercellular CO 2 concentration (Ci) showed a trend opposite to Pn: CK > HS > LS.
Gastric juice and peripheral blood TBA levels showed a trend of aberrant expression in pediatric BRG patients, potentially guiding clinical diagnosis. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Received 2025 Apr 4; Accepted 2026 Feb 3; Collection date 2026.
( Fig 7c , S39-S41 Tables in S1 File ) Height/half-length also showed a trend that resembled that observed in CI, with the post-hoc test displaying a considerable difference between each of those in the 20112014 range and those in the 20162018 range, with the former years demonstrating higher values ( d = 0.51–2.07, p < 0.01) ( Fig 7d , S42-S44 Tables in S1 File ).
The cases with follow-up questions showed a trend of higher scores and less discrepancy as the case evolved.
In terms of OS, patients with cutaneous metastasis only showed a trend toward better survival than those with multiple-organ metastasis; however, the difference was not statistically significant ( P = 0.1139).
Additionally, a larger study showed a trend toward reduced OS in patients with MLH1 -methylated ECs following ICI therapy. 33 However, these observations have not been confirmed in larger biomarker exploratory analyses conducted across three different clinical trials.
Quantitative analysis of CD11c+ DCs and CD8+ T cells indicated a significantly positive correlation between them (P = 9.92 × 10 −9 ; Supplementary Figure S1A–C ), and clarified that the CD11c-low group exhibited worse RFS (P < 0.001) and OS (P < 0.001), while the CD8-low group only showed a trend towards unfavourable RFS and OS ( Fig. 1 K and L).
138107.90 ± 45,326.40, P < 0.001).Notably, total TG measured by conventional clinical assay showed a trend toward lower levels in DLB but did not reach statistical significance (P = 0.079, Table 1 ).
All four groups showed a trend toward recovery; however, the control group showed the worst recovery, while the autograft group exhibited the overall best trend and fastest recovery.
The results showed that in mice administered free SCHB, all the genes tested showed a trend of increase compared with the Model group, but the differences were not significant.
Our subgroup analysis indicated that patients with a BMI <28kg/m 2 showed a trend of reduced risk of MACEs.
After 30 minutes, all groups showed a trend toward an increase, with the Stellest exhibiting the greatest short-term increase (+29.9 μV); however, these changes did not attain statistical significance ( P = 0.742).
TGF-β signaling was modestly enhanced by VitD, but showed no increase with PDT, and showed a trend toward downregulation when VitD and PDT were combined.
In the BLA, no significant group differences were observed, although NEX (Cre/Cre) mice showed a trend toward lower spine density (Figure 4J ).