“showed a trend”

While AshwaSR 300 mg showed significant reduction on day 60 from baseline, the AshwaSR 150 mg group also showed a trend of decreasing cortisol levels over the study duration.

circRMST showed a trend of higher abundance in SCLC-A compared to SCLC-N and SCLC-P ( Figure 1G ).

Although the meta-analysis showed a trend of improvement in some cognitive indicators (such as MoCA), these findings should be interpreted with caution.

Discussion In our study, in the daratumumab-treated cohort, patients with 1q gain or amplification showed a trend towards a shorter PFS and patients with 1q amplification presented with a shorter OS, consistent with the concept that amplification reflects a more advanced cytogenetic event.

7 Interestingly, the more distal outcome, renal failure, showed a trend toward a lower hazard (HR 0.91, 95% CI 0.70–1.17), although both confidence intervals were wide and included the null. 4.1 Potential mechanisms The observed benefits likely stem from the complementary mechanisms of both drug classes.

Although this difference did not reach the traditional level of statistical significance, it showed a trend that may have clinical importance—IMA-P can better ensure blood supply, thus avoiding excessive resection.

In the roots, the ZT content showed a trend of first decreasing and then increasing in G3 and WL168.

The 6 studies that did not report statistically significant improvement showed a trend toward improved parent wellbeing on outcome measure scores.

Regarding the trend over time, at any dose (10 Gy, 20 Gy, 30 Gy, and 40 Gy), both photon and proton therapies showed a trend of decreasing CD68 expression over time (Fig. 4 ).

Neither current nor past alcohol use impacted retinal aging ( P > 0.05 for both), although current alcohol use showed a trend toward a lower retinal age gap, indicating a possible protective effect ( Fig 4 ).

In our study, A549 sEVs showed a trend toward increased fucosylation compared with BEAS-2B sEVs, although this difference did not reach statistical significance.

Overall, The MVC Group showed a trend of decreasing first and then increasing slowly.

The relative abundance of Prevotella 1 in the experimental group showed a trend of decreasing with the increase of the concentrate to roughage ratio.

Fruit quality analysis Analysis of the effect of planting years on the quality of pears showed that ( Figure 1 ), with the increase of planting years, sucrose, reducing sugar and Vc content in pears showed a trend of first increasing and then decreasing, which was manifested as T30 ≈ T20 > T40 > T5.

However, patients who developed T790M-positive disease after progression on previous EGFR-TKIs and had a high expression (above median) of either CD73, CD39, HLA-E or NKp46 in the pre-osi biopsy specimen, showed a trend towards shorter PFS when treated with osimertinib than the patients with biopsies with low expression (under median) of any of the markers ( Table 2 ).

The landmark analysis starting 6 months post-procedure indicated that patients with an increased age gap post-CABG showed a trend towards higher mortality risk compared with those with a decreased age gap, though this did not reach statistical significance (HR 1.51, 95% CI 0.94–2.41; P = 0.09).

After GMK treatment, the gut microbiota composition showed a trend toward normalization (Fig. 6 M).

Similarly, bone samples from MPSIVA mice showed a trend toward increased expression of Il1a , together with Il1b and Mmp1 , compared with those from controls, highlighting an altered inflammatory state in tissues that are also primarily affected in patients ( Fig. 6C ).

These tumors also showed a trend toward increased microglia at the tumor site and a significantly higher fraction of Vista-expressing microglia ( Figures 7 C and 7D), suggesting that tumor-derived Igsf11 induces the expression of its receptor on microglia in a feedforward loop.

Although not statistically significant, most of the other functional gene sets also showed a trend toward relaxed selection ( Table 2 ; Table S6 ).

While Il6 expression showed minimal increases in the GWI model, except for in the cortex, etanercept/mifepristone treatment showed a trend for reducing Il6 levels in all brain areas.

Previous studies have emphasized that inadequate plaque control is the most direct cause of gingivitis and subsequent progression to periodontitis.[ 6 ] Interestingly, physical inactivity showed a trend towards increased periodontal risk, though not statistically significant in regression analysis.

4 Among controls, women had increased CMSI scores compared with men only in the high SR group, and both men and women showed a trend towards increased PHQ-12 with high SR.

A markedly positive CFB (>7%) was associated with higher ICU mortality and greater respiratory support requirements, whereas a markedly negative CFB (<−3%) showed a trend towards less favourable renal outcomes.

Additionally, the expression values of APOC4 and CDH1 measured by ELISA showed a trend to be correlated with those obtained by Tymora analysis in the discovery study (see Figure S1 ).