Although higher PTV and BED showed a trend towards worse PFS, neither were statistically significant, suggesting that the most predictive factor of progression was a change in NLR.
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In contrast, among patients without MPR, adjuvant therapy showed a trend toward better DFS, although this did not reach statistical significance ( p = 0.188).
Craniocaudal tumor dimension ≥ 40 mm showed a trend toward association with FFR but did not reach statistical significance after adjustment (HR = 2.02, 95% CI = 0.91–4.49, p = 0.084).
The averaged %Imp-drop demonstrated the highest AUC value among all measured parameters and showed a trend toward a higher in the AUC value compared with the unfiltered %Imp-drop, although the difference was not statistically significant (AUC = 0.93 vs. 0.91, P = 0.13).
CbzPEG 6 –NMeLeu17A2 showed a trend that is superior to NMeLeu13A2 in cardiac protection.
Notably, several combinations with TLR8 or TLR9 agonists showed a trend in lowering the expression of CTLA-4 in both CMV- and EBV- specific CD8+ T cells ( Figure 2(C,D) ).
In particular, (E, Z)-2,6-nonadienal showed a trend, in which the initial measured concentration decreased rapidly in the first week to approximately 75% of the initial concentration.
While diabetes mellitus showed a trend toward higher infective cases, the lack of strong statistical significance suggests that more research is needed to understand the relationship between chronic conditions and infection risk.[ 15 ] The significant difference between acute and chronic cases highlights the importance of timely diagnosis.
tcer-1;lipl-2 mutants expressing hLAL/LIPA showed a trend towards enhanced brood size compared to the double mutant alone, but this did not achieve statistical significance ( Fig 6D ).
However, 3 days after 5-FU wash out, aged organoids showed a trend towards an increase in apoptosis (Fig. 3f ), in line with the morphology analysis (Fig. 3b,c ).
Other inflammatory genes such as Tnf, Il6, Il10, Cxcl2 and Ifnb also showed a trend towards higher expression levels in the lungs of RPC mice at this time point.
Samples from 3 young (29–48 years) and 6 old (69–87 years) donors showed a trend for poorer fusion of myoblasts from older (33.7%) compared to younger (56.7%) adults (Fulle et al. 2005 ).
We found that the PNS group showed a trend toward lower incidence rates of HAEC and total complications across all subgroups.
In the CD62L low Th7R subset, the high group showed a trend toward better PFS and OS (Supplementary Fig. 5 ).
Tuvusertib upregulates the death receptor TRAIL-R2, immune checkpoint ligand PD-L1, and NKG2D ligand ULBP-1 in DU145 cells Gene expression analysis of tuvusertib-exposed DU145 and 22RV1 cells showed a trend toward increased expression of immune checkpoint ligands, increased antigen processing machinery, and decreased expression of immunosuppressive factors (Fig. 2 A,B).
Patients with type 3 morphology showed a trend toward worse outcomes.
Beta diversity analysis further confirmed significant differences in community structure among groups, specifically showing a significant separation of GMstructure between the NR-FMT group and the R-FMT group, and after SYP intervention, the NR-FMT group’s microbiota structure showed a trend towards shifting towards the R-FMT group.
Butanoic acid levels showed a trend toward an increase, further supporting the hypothesis that liensinine rescues disrupted microbial metabolic functions.
The serum of patients with NMOSD showed a trend of increased IL-1β concentrations compared to HC, although the difference was not statistically significant (Fig. 8 b).
While SQL showed a trend toward improved lung function on imaging and modest effects on collagen deposits, it significantly reduced PAH in the Fra-2 mice, improving key cardiac hemodynamic parameters and showing trends of beneficial effects on vascular remodeling.
Notably, patients treated with HCQ showed a trend toward reduced neutrophil ROS and decreased serum levels of the NET marker (citH3), consistent with previous clinical observations ( Figure 5 c and Figure S6 ) [ 33 ].
demonstrated that performing a CT scan of the complete lung fields before AE does not significantly affect radiation dose, contrast volume or procedure duration, although their results showed a trend towards shorter procedure times when CTA was performed [ 37 ].
PL1) showed a trend toward worse prognosis but did not reach statistical significance.
Notably, the HJBE3 group showed a trend of decreased growth and nutrient utilization efficiency at the highest inclusion level.
The body-length and the thoracic circumference of the newborn lambs were not significantly affected by pregnancy rank or treatment, although AOx supplementation showed a trend to promote thoracic perimeter.