Among these patients, those who received systemic chemotherapy in addition to EGFR-TKI therapy showed a trend toward improved PFS and OS.
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The current study showed a trend for less variability among clones compared to human talkers, with differences of 13 versus 19 percentage points for meaningful sentences and 12 versus 17 percentage points for nonsense sentences.
While both mMRC score ≥2 and radiological progression showed a trend toward increased mortality risk, these associations did not reach statistical significance as shown in Table 4 .
5a, b ); immunofluorescence analysis of tumor tissues showed a trend toward increased B-cell infiltration after STING agonist-treatment versus control (Supplementary Fig. 5c, d ).
CMA score showed a trend towards a reduction selectively in the RPE (RPE65 + BEST1 + cells) of patients with AMD (Fig. 1B ) compared to other cell types within the subretinal space (Fig.
Vimentin expression showed a trend toward increased levels in the mucosa of mock‐treated progeroid mice, though this did not reach statistical significance (Figure S6A,B ). α‐SMA staining revealed no evidence of myofibroblast activation, indicating an early fibrotic stage (Figure S6A ). qPCR analysis of plasminogen activator inhibitor‐1 (Pai‐1) and Tgfb1 in total colonic extracts indicated a trend toward increased expression in mock Lmna G609G/G609G mice, though these differences did not reach statistical significance (Figure 3D ).
Results PFA showed a trend toward lower recurrence rates (RR = 0.86, 95 % CI: 0.70–1.04), particularly in paroxysmal AF (RR = 0.83, 95 % CI: 0.68–1.01), while outcomes in persistent AF were comparable (RR = 0.98, 95 % CI: 0.69–1.38).
The study also showed a trend toward improved HbA1c at 3 months.
AdipoRon administration to DHT-treated rats restored complex IV activity and showed a trend toward increased citrate synthase activity in SAT, highlighting its potential to improve mitochondrial function.
Confirming the latter observation, we detected significant higher frequencies of Cd11b + Ly6G – Lys6C + monocytes in the livers of Tgr5 −/− compared to WT littermates ( Figures 2 E and S2 A), while frequencies of neutrophils (Cd11b + Ly6G + Lys6C − ) in the livers of Tgr5 −/− mice showed a trend toward upregulation but did not reach statistical significance ( Figure S2 B).
In the MASQ model, General Distress showed a trend-level positive effect on IM composite linear slopes, and secondary analyses revealed a significant positive effect on IL6 linear slopes.
42 MJD patients showed a trend towards decreased amplitude and a phase advance, indicating an earlier peak activity time as the disease progressed ( Supplementary Fig. 1C ).
The results showed a trend similar to that observed in TH (+) immunofluorescence staining.
While differences between medication classes did not reach statistical significance, GLP-1 RAs showed a trend toward greater efficacy at 18 and 24 months[ 95 ].
The waterbird diversity showed a trend of first decreasing and then increasing during 2013–2022.
This was accompanied by augmented mRNA levels of Cdkn1a and kidney injury marker Havcr1 in the kidneys of EC-KO vehicle-treated mice, which showed a trend of down-regulation after treatment with SUL-138 without reaching statistical significance ( Figure 4F–G ). mRNA expression of kidney injury marker Lcn2 and fibrosis marker Col1a1 showed a trend of being increased in EC-KO vehicle-treated mice without reaching statistical significance.
The ≥41 years group showed a trend toward lower implantation rates, although not statistically significant (OR=0.310; 95% CI: 0.082-1.176; p =0.085).
The glial per knockout ( repo-gal4 > per CRISPR ) significantly reduced survival to starvation in two out of three experiments and the third experiment also showed a trend toward reduced survival ( Figure 5a and Suppl.
Several other features showed a trend as reflected by higher P values though not reaching statistical significance, which may be attributed to center-specific expertise, patient populations and particularly clinical subspecializations.
No significant differences were observed between the MMF and model groups; however, MMF treatment showed a trend toward the recovery of microbial richness and diversity. 3.3.3.
Results Combined treatment with donepezil and microcurrent showed a trend toward improved cognitive performance and reduced pathology compared to donepezil alone, although these differences were not statistically significant.
Although seven CPMs showed a trend toward reduced serum IgE, none reached statistical significance; Xinqin Granules (XG) ranked highest (SUCRA 76.9%).
While vB_MZM_2AB-P showed a trend towards better thermal stability compared to vB_MZM_4AB-P under high-temperature conditions, however, no significant difference was observed overall ( p = 0.15).
The results of our study showed that the risk of the primary composite endpoint of cardiac mortality, ischemic stroke/TIA/systemic thromboembolism, and major bleeding events was not significantly different; however, the HR of the Cox regression showed a trend of superiority of the OAC group.
AA ameliorated chronic colitis in IL-10−/− mice In IL-10−/− mice, AA treatment showed a trend toward reduced body weight loss compared to the vehicle group, although the difference was not statistically significant ( Figure 5(a) ).