“showed a trend”

Interestingly, the presence of amiloride in combination with LEFTY2 pre-treatment showed a trend towards an even greater reduction in [Ca 2+ ] i , though this combined effect did not achieve statistical significance, as indicated in Figures 2a, b, f . 3.3 LEFTY2 attenuates trypsin-induced upregulation of L-type calcium channels The previous results showed that decrease of calcium does not occur by blocking ENaC.

[ 5 ] showed a trend toward ICG-FA reducing rates of anastomotic leak but did not reach significance, and the PILLAR III industry-funded RCT was terminated early due to slow recruitment [ 6 ].

The other 7 HFpEF pigs showed a trend toward decreased HR responses to the test compared to their healthy baseline and to 3 lean controls.

Co‐treatment of medin with RO106‐9920 in VSMCs showed a trend (not statistically significant) towards reduced IL‐6, IL‐8, and MCP‐1 gene expression versus medin treatment (Figure 3a–c ).

The findings showed a trend similar to that of the overall population across all services.

ALT levels showed a trend towards an increase in FPC versus ND, while AST and serum cholesterol remained unchanged (Figure S1 ).

In contrast, in early tumor shrinkage–negative patients on bevacizumab-based therapy showed a trend toward better overall survival, PFS, and postprogression survival outcomes compared with patients on anti-EGFR–based therapy (overall survival, HR = 1.22 [95% CI = 1.00 to 1.48]; PFS, HR = 1.27 [95% CI = 1.05 to 1.53]; postprogression survival, HR = 1.13 [95% CI = 0.90 to 1.43]).

Although the M treatment showed a trend toward increased biomass, this change was not statistically significant.

RQ analysis further revealed sex-specific differences: males showed a trend toward increased nighttime RQ, whereas females exhibited a significant daytime increase, suggesting enhanced carbohydrate utilization under TRF ( Figure 4 F).

Additionally, a sensitivity analysis, excluding patients in the RVP group who underwent RVP after the introduction of LBBAP, showed a trend consistent with the main results (Supporting Information S1: Table S5 ).

Although the patient cohort was small, the results showed a trend of increased expression levels of miR‐33a and miR‐126 in the patient groups compared to healthy controls, while miR‐145 expression showed a decreasing trend in the patient groups ( Figure 6 A ).

LCN2, also known as NGAL, showed a trend towards high intensity in colitis and nephritis patients at the Tox and Management time points.

Indeed, many pro‐apoptotic genes downstream of the ATF4‐eIF2S1 pathway [ 64 ], such as DDIT3 and TRIB3 , showed a trend for increased expression upon TriC treatment.

KRAS ‐mutated MSS samples showed a trend toward having lower activation of immune response pathways, that is, having significantly lower activities in JAK–STAT and NFkB pathways relative to the RAS_RAF_GNAS_wt MSS samples in the second patient cluster (Fig. 4A ).

Group A showed a trend towards better results from ILESIs over TFESIs (62% [95% CI: 55–69%]) vs 50% [95% CI: 41–59%]), while there was no difference in success rates from ILESI vs TFESI in Group B (38% [95% CI: 14–62%] vs 38% [95% CI: 26–50%]).

In proliferative LN, the RVLs group showed a trend toward a lower renal survival rate compared to the NRVLs group, although this difference was not statistically significant ( Fig. 3 b).

Additionally, anxiety showed a trend towards being a predictor of gingival/periodontal disease, with a p ‐value of 0.069, but this relationship was not statistically significant at the 5% level.

Similarly, cardiovascular disease status showed a significant interaction ( p for interaction = 0.01), with those free of cardiovascular disease (OR = 0 .91, 95%CI: 0.86–0.96) demonstrating protective effects, whereas patients with cardiovascular disease (OR = 1 .26, 95%CI: 0.97–1.63) showed a trend toward increased risk, though not reaching statistical significance.

Although not statistically significant, our data showed a trend toward improved OS in patients who received immunotherapy rechallenge (12.77 vs. 9.17 months), consistent with previous studies.

The plot also showed a trend towards a higher difference in SDM-Q scores (Q-9 minus Q-Doc) with increasing mean scores (Fig. 6 ).

The comparison between stroke and AUVP showed a trend but did not reach statistical significance ( p = 0.055).

The gene expressions of the Toll-like receptor 4 (TLR4) pathway ( irf3, irak4, traf6, and tbk1 ) in the liver showed a trend of upregulation, while those in muscle development-related genes ( myog, myod, mstn, myf5, and fgf6b ) were downregulated after PSNAP exposure by trophic transfer ( Table 6 ).

The S-PN group showed a trend of increased smac expression and similar levels of caspase-8 expression compared to the Model group, suggesting that S-PN may enhance SMAC-mediated activation of Caspase, though this activation does not appear to target caspase-8.

The mITT analysis, which excluded patients who discontinued treatment, showed a trend toward increased Breg levels, consistent with the ITT analysis, though it did not reach statistical significance.

Myxomycete community assembly processes The R 2 of Sloan's neutral community model showed a trend of CBF (0.476) >CF (0.444) >MBF (0.360) >BF (0.217) ( Fig. 5A through D ), suggesting that deterministic processes predominantly governed myxomycete community assembly.