In the steroid group, patients who successfully maintained the imatinib dosage showed a trend toward more favorable survival outcomes than those who did not (3-year PFS, 73.3% vs. 44.4%, p = 0.34; 3-year OS, 95.8% vs. 75.0%, p = 0.15, respectively).
Affected ankle dorsiflexion strength least squared z-scores also showed a trend towards improvement over the follow-up period, without reaching statistical significance ( p = 0.34).
Yet, in BMDMs that engulfed ACs, Wdfy3 knockout BMDMs showed a trend of higher F-actin signals (Fig. 2g , right panel, P = 0.34).
In contrast, the North region (R 2 : 39.0%; p = 0.030) showed a trend of significant and not constant increase (second order model), while the South region (R 2 : 22.0%, p = 0.340) showed a stable trend ( Table 2 ).
In one recent randomized, double-blind study comparing the prophylactic efficacy of immediate-release CBZ and lithium in bipolar disorder, lithium was superior to immediate-release CBZ in terms of 2.5-year hospitalization rates (lithium, 26%; immediate-release CBZ, 62%; p = 0.012) in patients with “classical” bipolar I disorder (without mood-incongruent features and psychiatric comorbidity and without mixed states; n = 67), while immediate-release CBZ showed a trend toward being more effective (2.5-year hospitalization rates: lithium, 44%; immediate-release CBZ, 31%; p = 0.34) in the more heterogeneous “nonclassical” subgroup of patients (n = 104).These findings suggest that patients with classical features benefit more from prophylactic therapy with lithium, while those with nonclassical features may benefit more from prophylaxis with CBZ, which appears to provide a broader spectrum of activity ( Greil et al 1998 ; Kleindienst et al 2000 ).
LLMs showed a trend toward better performance on low-order, knowledge-based questions ( p = 0.34), whereas doctors tended to perform better on simple case-based questions ( p = 0.74), particularly those requiring higher-order clinical reasoning ( p = 0.10).
Participants with haemophilia B ( N = 42, 13%) showed a trend towards better adherence than participants with haemophilia A (score: 17 vs. 13, p = .34).
A recent study[ 4 ] analyzed 20 patients diagnosed with PAIS obtaining a median overall survival of 17 mo: Patients who received postoperative chemo and radiotherapy showed a trend towards better survival compared to those who had surgery alone (24 mo vs 8 mo, P = 0.3417).
Patients who received post-operative chemo- and radio-therapy showed a trend towards better survival compared to those who had surgery alone (24 vs 8 months, P = 0.3417).
Median PFS showed a trend favoring THPy (19.80 months vs 15.57 months; Log-rank P = .343).
Patients with endometriosis and no resection showed a trend towards a lower pregnancy rate (17.6%) compared to patients that underwent complete resection ( p = 0.346) and also compared to patients without endometriosis ( p = 0.370).
While overdosing showed a trend towards increased bleeding risk compared to underdosing in our study (HR 1.39, 95 % CI 0.70–2.78, p = 0.35), this finding was not statistically significant.
Tumors with mutations at codon positions 32–34 showed a trend with improved EFS than those at 35–37 or 41 (log-rank P = 0.35).
Although LUSC showed a trend toward elevated PRS compared to controls, the association was not statistically significant ( P = 0.35).
IDH1 mutational subclasses were associated with a trend toward better OS (R132C, HR = 0.86, p = 0.5; R132H, HR = 0.89, p = 0.6), whereas IDH2 R140 showed a trend toward inferior OS (HR = 1.1, p = 0.35).
FIB-4 also showed a trend toward a more prominent reduction in the MVC + DRV/r arm (−0.02; IQR −0.21 to +0.13) vs 3-drug ART arm (+0.02; IQR −0.23 to +0.20) ( P = 0.35) at week 48 (Fig. 1 B).
In particular, when compared to the E7 wt, with or without the NAL modification in p4, the efficacy of E7-scaff peptides showed a trend of improvement which did not reach the statistical significance (p = 0.35) ( Figures 6A, B ).
Considering only the three trials of higher quality (HR, 0.82; 95% CI, 0.70-0.96) [ 11 , 15 , 20 ], the results did not differ significantly compared to all eight trials (HR, 0.77; 95% CI, 0.67-0.88) Despite a suboptimal regime which was standard at the time recruitment started, the two randomized trials investigating the effect of systemic adjuvant therapy with 5 FU/FA showed a trend towards a better RFS in one study (39 months vs. 20 months; HR, 0.78; 95% CI, 0.46-1.32; p = 0.35) [ 17 ], and a significant improvement in RFS in the other trial (24.4 months vs. 17.6 months; HR, 0.66; 95% CI, 0.46-0.96; p = 0.028) [ 20 ].
In the 142 grade II gliomas, 45 IDHmut-OT tumors showed a trend of better prognosis than 24 IDHwt tumors in Kaplan-Meier's curve ( p = 0.351), which in turn showed a trend of better prognosis than 65 IDHmut tumors ( p = 0.097), followed by 8 IDHwt-ET tumors ( p = 0.0001) (Fig. 4b ).
Subgroup analyses Patients after OHCA (Additional file 1 : Table S4) showed a trend towards higher 30-day mortality rate when treated with balanced crystalloids group that did not reach statistical significance (53.2% vs 46.7%, p = 0.356, Fig. 4 A).
In contrast, the OF 3 group only showed a trend toward a lower use of analgesics without significant changes at either time point (2 days postoperatively: P = .357; discharge: P = .177).
However,decreased BMI(median OS 8.9 vs 9.3 months; HR 1.218, 95% CI 0.936–1.585; P = 0.142; Fig 4B ) showed a trend to worse prognosisand BMI at diagnosis did not influence on OS ( P = 0.357).
Even if transaminases (AST) and lactate-dehydrogenase (LDH) showed a trend toward increase, this was not significant ( p = 0.358).
Generally, the expression level of SLCO1B3 showed a trend of decreasing throughout the laying cycle ( P -value = 0.36) ( Figure 2 ).
PARP inhibitors combined with chemotherapy significantly improved PFS (hazard ratio [HR] 0.73, 95% confidence interval [CI] 0.63-0.84, P < .0001) and showed a trend towards improved OS (HR 0.93, 95% CI 0.79-1.09, P = .36), though this was not statistically significant.