showed a trendp = 0.1380
Changes in the Expression of Inflammatory Pathway Proteins In the liver homogenates, we showed a trend toward an increase in the expression of NF-κβ at the end of the experiment (fifth week: p = 0.1380; Figure 5 A).
Changes in the Expression of Inflammatory Pathway Proteins In the liver homogenates, we showed a trend toward an increase in the expression of NF-κβ at the end of the experiment (fifth week: p = 0.1380; Figure 5 A).
Multiple-injured patients with A-type spinal injuries showed a trend towards a lower overall injury severity compared to multiple-injured patients with B-/C-type spinal injuries (ISS: 22.75 vs. 26.36, respectively; p = 0.138).
HER2 positivity showed a trend toward improved OS on multivariable analysis (HR 0.68, 95% CI 0.40–1.13; p = 0.138), though this did not retain statistical significance, likely due to the limited number of HER2-positive patients (n = 23).
The generalized HCR group showed a trend toward lower cumulative MACCE rates than did the OPCABG group (9.9% vs. 16.2%; HR, 0.567; 95% CL, 0.268–1.201; P = 0.138), but the differences were not statistically significant.
Patients with no less than 54.4ng/ml in AFP BL showed a trend with better RFS than those who did not ( p = 0.138, Supplemental Materials Figure 1D ).
Although ADC mean showed a trend toward higher values in responding lesions ( P = 0.1386), no statistically significant association was found.
The median age of participants in these trials ranged from 62 years to 78.5 years and showed a trend upwards over time ( p = 0.1388).
Additionally, a multivariable Cox regression analysis showed a trend toward association with poorer overall survival (HR = 1.695, 95% CI: 0.842–3.414, p = 0.139), with several individual genes such as RNF24 (HR = 1.887, CI: 1.378–2.583, P = 7.55 × 10 −5 ) and CEP170 (HR = 1.681, CI: 1.147–2.465, P = 7.55e × 10 −3 ) being independently associated with prognosis ( Figure 6D ).
Group B had a higher rate of aortic root replacement (44% vs 35%, P = .008), lower ascending aorta and hemiarch replacement (40% vs 53%, P = .013) and showed a trend towards more extensive distal aortic repairs: total arch replacement (27% vs 20%, P = .139) and frozen elephant trunk (20% vs 14%, P = .171).
Smoking history showed a trend toward increased recurrence risk with a HR of 1.61 (95% CI 0.85–3.04, p = 0.14), though this did not reach statistical significance.
While S1 showed a trend towards worse prognosis when compared to S2, this difference was not statistically significant in cox regression analysis ( p = 0.14).
The combined diet significantly improved the rod signaling pathway between P30 and P60 (rod bipolar cell b- wave amplitude; P30, 353.9 ± 16.1 μV; P60, 400.8 ± 14.0 μV; p = 0.04; n = 13 eyes/group) and showed a trend towards an increase in the cone signaling pathway (cone bipolar cell b- wave amplitude; P30, 134.4 ± 11.1 μV; P60, 159.0 ± 11.8 μV; p = 0.14; n = 13 eyes/group) ( Fig. 4 G ).
Depression Before proton beam therapy, the study cohort had a mean depression score of 4.36 (CI 3.63–5.09) and showed a trend for improvement of depression to 3.67 (CI 2.93–4.41) at 2 years ( β = 0.693; SE = 0.47; p = .140; Table 2 ).
Furthermore, second interim analysis of IMspire150 showed a trend toward prolonged mOS in the atezolizumab group compared with the control group (39.0 vs. 25.8 months, p = 0.14) [ 22 ].
We observed that the presence of any preexisting microhemorrhages showed a trend toward increased incidence of ARIAs (16% of 56 patients with no microhemorrhages vs. 36% of 14 patients with one or more microhemorrhage; Fisher exact test, p = 0.14; Table 3 ).
Non-GDM mothers with BMI <25 showed a trend for higher I-FABP level (r=-0.35; p=0.14). 3.2.
Overall Gprc5b levels, determined with a primer set (A/a) that amplifies a region common to both Gprc5b_v1 and v2, showed a trend towards an increase on day 17 (1.8 fold; p = 0.14) after normalization to beta-actin levels ( Fig. 4A , 3 rd panel from top ).
Only the model built on CDT score showed a trend to significance (F (22, 31) = 1,52; p = 0.14), suggesting that CDT score could be positively associated with the APOEε3 allele (2,2; 95% CI [0,03 0,8]; p = 0.037).
In regions with low VEGFR2 expression, this difference was not significant but again showed a trend toward higher expression in HPV-negative tumors ( Figure 3 A; p = 0.140).
Patients with high activated CD8 + T cells infiltration showed a trend towards better OS (Fig. 7 C, P = 0.140).
Although hypofractionation showed a trend toward poorer outcomes compared with hyperfractionation (HR, 2.077; 95% CI, 0.788–5.478; p = 0.140), this difference did not reach statistical significance, likely due to the relatively small sample size in this group ( n = 17).
Interestingly, the proliferative ability of zamto-cel as assessed by CD27 and CD127/IL-7R expression showed a trend for increased expression in patients with CR (CAR + CD4 + CD27 + in CR [mean, 86.2; 95% CI, 73.57-91.59] vs non-CR [mean, 60.98; 95% CI, 8.93-92.14; P = .14], CAR + CD4 + CD127/IL-7R + in CR [mean, 82.09; 95% CI, 76.97-88.93] vs non-CR [mean, 59.34; 95% CI, 29.87-82.48; P = .035], CAR + CD8 + CD27 + in CR [mean, 88.85; 95% CI, 82.09-94.46] vs non-CR [mean, 66.33; 95% CI, 16.55-94.01; P = .05] and CAR + CD8 + CD127/IL-7R + in CR [mean, 26.72; 95% CI, 15.52-43.95] vs non-CR [mean, 12.36; 95% CI, 1.93-49.96; P = .1]; Figure 3 A-B; supplemental Figure 6 C).
Mdivi-1 (25 μM) for 3 days significantly reduced type III collagen production in MCT-RVfib, while P110 (1 mM) for 3 days showed a trend ( P = 0.14) in reducing type III collagen production in MCT-RVfib ( Figure 3 ).
The high/intermediate-TIL group showed a trend toward better DFS ( p = 0.14, Fig. 3 b) and significantly better OS ( p = 0.03, Fig. 3 d) than the low-TIL group by the average method, although analysis using the hot-spot data did not show any significant difference either in DFS or OS (Fig. 3 a, c).
The results were similar when multiple imputation was performed (RR, 1.23; 95% CI, 0.80–1.88, P = 0.35). The frequency of treatment failure was significantly associated with TNM stage (Table 2 ) and showed a trend towards an association with tumour differentiation ( P = 0.14).