In a comparison of facilities treating > 100 patients and facilities treating ≤ 50 patients per year, centers with many patients showed a trend for increased rates of using SRT for up to 10 BM (43 % vs. 19 %; p = 0.13), while HS-WBRT and memantine were equally frequently applied ( Fig. 4 b).
Similarly, KB showed a trend for attenuation of HDM exposure induced IL-13 levels (p = 0.13).
Excluding the 8 infants who were studied at both time points, HEU infants showed a trend toward higher NK cell proportions at 6 months compared to birth (increase from median of 1.85% at birth to 3.12% at 6 months; p = 0.13), whereas HUU infants had lower NK cell proportions at 6 months compared to birth (decrease from 9.4% at birth to 4.65% at 6 months; p < 0.0001).
In these cases, LFP duration increased from 232 ± 27.7 ms in control to 624 ± 150 ms ( p = 0.002) (i.e., 2.7-fold), whereas the LFP rate showed a trend to rise from 42.3 ± 7.2/min to 57.3 ± 15.6 events/min ( p = 0.13). 3.3.
While diabetes mellitus showed a trend toward association with HFpEF in univariate analysis (OR 1.33, 95% CI 0.92–1.92, P = 0.13), it did not reach statistical significance for inclusion in our final model. 3.3.
Women who underwent early PBO also showed a trend of greater tau deposition compared to the referent women after adjusting for age (PBO p = 0.13), or for age and APOE ε4 status (PBO p = 0.16), but this difference did not reach statistical significance (Table 2 ).
In the LUAD-like group, continuing EGFR-TKI treatment showed a trend towards longer PFS compared to discontinuation (6.2 months (95%CI, 4.4–8.0 months) vs. 3.6 months (95%CI, 1.2–6.1 months), p = 0.13).
Similarly, in the second revision of the international staging system (R2-ISS) which utilized 15 pooled clinical trials for model building, while t(14;16) showed a trend towards a shorter PFS, it was not statistically significant (HR 1.15 [95% CI, 0.96 to 1.37], P = 0.13) which could have potentially been impacted by the heterogeneity of the dataset and the therapies received [ 12 ].
Infants fed the donor milk supplement showed a trend toward slower weight gain than those fed a formula supplement (p = 0.13).
4%, HR 8.9, 95% CI 3.0–26.0, P < 0.01), whereas patients with EuroSCORE II scores above the 75 th percentile (> 6.8) only showed a trend towards higher mortality (18% vs. 9%, HR 2.1, 95% CI 0.8–5.6, P = 0.13).
To this end, OS cells were shown to express several components of the WNT signaling pathway and the chemotactic response to exogenous WNT was increased in a mouse metastatic OS cell line compared to the parental cells with low metastatic potential, and increased WNT10B expression showed a trend (n = 44; P = 0.13) to shorter survival in patients [ 45 , 46 ].
Analysis of protein synthesis in acinar cells from wild type and Nfic -/- mice using flow cytometry showed a trend, albeit non-significant ( P = 0.13), towards reduced translation in KO pancreata (Supplementary Fig. 8D ).
Picolinic acid addition showed a trend (p = 0.13) toward increased lifespan.
Further, both the stroke groups showed a trend of shorter compensatory steps than healthy older adults ( p = 0.13).
The effect of sex on stromal thickness in the central 2 mm region was not significant, although it showed a trend towards stromal thinning in females ( P =0.131, Table 2 , t -test).
In terms of medical record access, ROI patients showed a trend towards improved access (37% vs 26%, p=0.131), though the majority of patients in both regions expressed a desire for regular access to their records.
Although non-significant (NS), patients with incongruent results (one low/one high, n = 10) showed a trend of having a favorable prognosis compared to patients with high results from both modalities (log-rank p = 0.131), but inferior compared to patients with low uPAR-estimates on both modalities (p = 0.136).
Moreover, women with EGFR mutant tumor treated with front-line CT and salvage anti-EGFR TKI showed a trend toward a better OS in comparison with those affected by EGFR wild-type tumor undergoing the same sequence (HR 0.560; p = 0.131).
We found that overexpression of WDR66 showed a trend toward an increase of CD10+ cells in RPMI 2650 (p=0.1313), while a decrease in CD10+ (and CD184+) cells was observed in Detroit 562 ( Fig. 3 C ).
Although not reaching statistical significance, ID/IN patients showed a trend towards improvements in the sections’ reflexes (change: 0.5 ± 1.1, P = 0.132), lips (change: 1.1 ± 3.9, P = 0.360), and tongue (change: 0.5 ± 1.9, P = 0.389).
The AE37 arm had no difference in DFS as compared to CG, but pre-specified exploratory subgroup analyses showed a trend towards benefit in advanced stage ( p = 0.132, HR 0.573 CI 0.275–1.193), HER2 under-expression ( p = 0.181, HR 0.756 CI 0.499–1.145), and triple-negative breast cancer ( p = 0.266, HR 0.443 CI 0.114–1.717).
In a different randomized trial in the adjuvant setting, AE37 and GP2, two other HER2 derived peptide vaccines were investigated in a four-arm, prospective, randomized, single-blinded, multi-center phase II trial; the AE37 arm showed no difference in DFS overall; however, subgroup analyses showed a trend towards benefit in advanced stage ( p = 0.132, HR 0.573 CI 0.275–1.193), HER2 under-expression ( p = 0.181, HR 0.756 CI 0.499–1.145), and triple-negative breast cancer ( p = 0.266, HR 0.443 CI 0.114–1.717).
Convexity meningiomas showed a trend toward lower odds of preoperative seizures (OR = 0.179; p = 0.132), although this was not statistically significant.
Regarding the influence of DIC, the Firmicutes:Bacteroidetes (F/B) ratio showed a trend of a numerical decrease ( P = 0.132) in the Salmonella trial with DIC (1.14 vs. 1.47 in the CTR group).
Although the 0 and ≥3 positive lesions groups showed a trend toward higher rates of clinical pregnancy ( P =0.132), these differences failed to reach statistical significance.