“showed a trend”

We found an association at p < 0.05 with a neuropathologic feature for 7 of the previously reported 44 index variants, while 9 other variants showed a trend at 0.05 < p < 0.10 (table e-5).

Likewise, harboring bulky disease showed a trend towards a lower likelihood of achieving a CR in MZL patients ( P =0.1; Online Supplementary Table S1 ).

The lowest dose of noribogaine tested at 12.5 mg/kg showed a trend ( p <0.10) in decreasing nicotine self-administration by 13% compared to vehicle.

Similarly, no significant association was observed between age groups and the risk of mild or moderate cognitive impairment, although adults aged >75 years showed a trend toward increased risk of moderate cognitive impairment (aOR = 2.76, 95% CI: 0.82-9.24, P = 0.100) compared to those aged 60–64 years.

4g, h ), whereas Aβ38 and Aβ40 were significantly increased and Aβ42 levels showed a trend for being elevated, p = 0.1 (Supplementary Fig. 4i , Fig. 4g, h ).

In Hulunbuir sheep, SIgA levels also increased ( P < 0.05), and Hu sheep showed a trend toward an increase (0.05 < P < 0.1).

It also showed a trend toward reducing IgY content ( P < 0.10).

KRAS wild-type individuals with non-overexpressed MKP-1 showed a trend towards longer OS, which was not statistically significant ( P =0.1).

For model building, we selected variables with significant statistical association or those that showed a trend ( p < 0.10) with respect to AVR indication.

Results Three of the 28 SNPs showed a trend to be associated with T2D in our first case-control set (P < 0.10).

Although the total numbers of GFP + thymocytes were unaffected, retroviral expression of Gfi1 in Lyl1 −/− progenitors permitted lymphoid development and showed a trend towards increased frequencies of T-lineage cells compared to GFP -transduced controls (p=0.1) suggesting that Gfi1 is a critical target of Lyl1 at the ETP stage, enabling thymic T cell lineage development.

Interestingly, T-AOC showed a trend with increased alfalfa content (0.05 < p < 0.10), and MDA was significantly lower than the other treatments ( p < 0.05).

Independent variables were those that showed a trend toward being significant in univariate analyses ( p < .1).

If the interaction between the Visual Stimulation Stages or Hypercapnic Test Stages and Age Groups was significant [or showed a trend to be significant (i.e., 0.05 ≤ p ≤ 0.100)], the magnitude of the response (i.e., absolute and relative delta values) for each age group were compared using independent 1-tailed Student T -Tests.

In contrast, the model with TNF-RII showed a trend toward statistical significance ( p ≤ 0.10) for MA21 with increasing TAA-PNC associated with a slight increase in TNF-RII. 3.5.

However, we did not find strong evidence that major discrimination experience amplified age-related decline in neurite density (the association showed a trend, P <.1).

The expression of CCL21 showed a trend toward a decrease with the CTLA4-Ig treatment ( p = 0.10; Fig. 4J ).

Pigs fed Zn-di-tripep showed a trend toward ( P ≤ 0.10) higher serum Zn concentrations compared to those fed ZnSO 4 at all evaluated times, with percentage increases of 6.6%, 5.5%, and 5.1% at 0, 1, and 3 h, respectively.

This experiment revealed that tumor-bearing mice treated with TM5441 (20 mg/kg daily) showed a trend to develop slower growing tumors that reached a volume of 1,500 mm 3 at an average of 25.8 (± 3.4) days vs. 21.2 (± 2.5) days for the control group ( P value = 0.10) ( Fig 5A and 5B ).

In the neostriatum, CrT −/y mice showed a trend towards increased DA (F(1,16) = 3.64, P<0.10); they had increased levels of 5-HIAA (F(1,16) = 12.41, P<0.01) and 5-HIAA/5-HT (F(1,16) = 11.63, P<0.01) compared with CrT +/y mice.

In addition, the metabolic modules “C5 isoprenoid biosynthesis, mevalonate pathway”, “FA biosynthesis and elongation” and “Cholesterol biosynthesis” associated to the pathways of terpenoid, FA and steroid synthesis showed a trend of modulation ( p ≤ 0.1) ( Supplementary Table S2 ).

Simple logistic regression analysis indicated that HOMA-IR (OR 1.442, 95% CI 1.123–1.852; P =0.004), TC (OR 1.280, 95% CI 1.050–1.560; P =0.014), LDL-C (OR 1.467, 95% CI 1.149–1.872; P =0.002), and hepcidin levels (OR 1.229, 95% CI 1.165–1.296; P <0.001) showed a trend ( P <0.10) toward an association with the presence of OSAS ( Table 2 ).

Run duration on the balance beam was significantly increased in Pink1 −/− animals and they showed a trend for more footslips ( P = 0.10; Fig. 2D and E ).

Provenzano et al 57 combined GEM with PEGPH20, a drug‐depleting HA, and observed significantly prolonged median survival (median overall survival of GEM‐ (55.5 days) and GEM + PEGPH20 (91.5 days)‐treated mice were significantly different ( P = 0.004); treatment with PEGPH20 alone showed a trend toward increased survival (median = 63 days) that did not reach statistical significance ( P = 0.1)).

The MVA-150 group also showed a trend (p=0.1) for delay in acquisition of SHIV infection with an estimated vaccine efficacy of 57%.