showed a trendp = 0.07
In men the LA-LV deviation angle showed a trend for greater angle (end-diastolic (ED) angle 26.9 ± 6.2° in women and 29.8 ± 5.9° in men, p = 0.07 and end-systolic (ES) angle 19.5 ± 5.9 and 22.6 ± 6.4, p = 0.06, respectively).
In men the LA-LV deviation angle showed a trend for greater angle (end-diastolic (ED) angle 26.9 ± 6.2° in women and 29.8 ± 5.9° in men, p = 0.07 and end-systolic (ES) angle 19.5 ± 5.9 and 22.6 ± 6.4, p = 0.06, respectively).
The mean Manders M2 coefficient was calculated for each subject, and Student’s t -test showed a trend ( T = −2.18, P = 0.07) towards increased overlap of GSK3β signal with nuclear staining in Control versus Alzheimer’s disease ( Fig. 4C ), providing likely validation of the mass spectrometry results.
Neutrophils showed a trend to increase in ELA groups (P < 0.07) ( Figure 10C ).
For HADS-A these individual transitions also showed a trend for overall changes between category groups ( p = 0.07).
Notably, the Bite + DSS group showed a trend toward less weight loss compared to DSS-only mice during recovery ( p = 0.07), suggesting possible modulation of disease course by bite exposure.
Class I mismatch was also significantly related to OS ( P = 0.01) and DRI showed a trend for OS ( P = 0.07), Supplementary Table .
DeLong’s test indicated that the hybrid model’s performance was significantly superior to that of the deep learning-only model ( P < 1 ×10−5) and showed a trend towards superiority over the radiomics-only model ( P = 0.07).
Potential confounding factors Although iron deficiency’s potential impact on PROs was not analyzed due to the low prevalence of abnormal hemoglobin levels (4.5% of the cohort), patients receiving iron supplementation ( n = 53) showed a trend toward lower SF-36 mental scores (mean MCS, 42) than untreated patients ( n = 133; mean MCS, 45; P = .07).
However, the mortality RR from six inpatient studies also showed a trend of increased mortality with HCQ with pooled RR of 1.09 (95% CI 0.99–1.20, I 2 = 0%, p = 0.07; Figure S2 ).
Modified O’Driscoll scores at 4 weeks post-operatively showed a trend toward improvement in cartilage repair quality in the SDF-1 group relative to the empty control group (13 ± 8 vs . 3 ± 1; P = 0.07); however, the difference was not statistically significant.
Further, male EAE mice showed a trend towards worse cardiac function at 2 months of recovery compared with at 1 month (LVEF: 49.53 ± 2.063 vs 54.57 ± 1.700, respectively; p = 0.07; LVFS: 24.82 ± 1.263 vs 27.82 ± 1.063, respectively; p = 0.08).
Furthermore, although stroke volume showed a trend towards lower values in WD-fed mice (36 ± 2 versus 45 ± 4 μL in control mice p = 0.07), cardiac output was unaltered compared to controls.
The comparison of the two groups showed a trend towards an earlier occurrence of infection in patients with biliary complications (p=0.07, Table 2 ).
The order CW040 (phylum TM7, previously shown in ruminal contents of dairy heifers, [ 25 ]) again showed a trend for significance between RFI groups ( p = 0.07) ( Supplementary Table S4 ).
Our data showed a trend of decreasing proportion of mild stroke (National Institutes of Health Stroke Scale [NIHSS] <4; 40.2% vs. 42.6%; OR, 0.91; P =0.07) and mild to moderate stroke (NIHSS <10; 73.3% vs. 76.0%; OR, 0.87; P =0.02) in 2020 compared with 2019.
Indeed, in a meta-analysis of almost 29,000 patients with COVID-19, use of RAAS inhibitors for any condition showed a trend to lower risk of death or critical events (odds ratio 0.67, 95% CI 0.43 to 1.03, p = 0.07).
Similarly, QoL in terms of physical functioning and pain showed a trend towards improvement eight weeks after initiation of treatment compared with baseline ( P = 0.070 and 0.081, respectively) (Fig 3a ).
Moreover, SOX2-negative cases showed a trend for a longer survival time when compared to those expressing this factor (80 months (CI 69-92) vs 42 months (CI 25-59), respectively; HR 2,8; p = 0.07).
Treatment of polarized ARPE-19 cells with 100 nM ZK for 3 h showed a trend (p = 0.07) to increase BECN1 expression in low autophagy-/UPR-related gene-expressing cells (Fig. 6 c) but significantly decreased BECN1, MAP1LC3B, mTOR, ATF6, DDIT3, EIF2AK3 and HSPA5 expression (Fig. 6 a,c,d,f,j,k,m) in high autophagy-/UPR-related gene-expressing cells.
In the Ang2 group, treatment with a combination of Ang2 siRNA + CS showed a trend toward decreased lung compliance ( p = 0.07) ( Figure 4B ) while in the CHOP group, treatment with CHOP siRNA + CS resulted in increased lung compliance than treatment with CHOP siRNA alone ( p = 0.05) ( Figure 4A ). miR34a Inh showed the best compliance with no significant difference in all the three groups (CS with ventilation, miR34a Inh with ventilation and miR34a Inh + CS with ventilation) studied ( Figure 4C ).
Multivariable analysis ( Supplementary Table , online only) showed a trend toward more MAEs in the PMSG group without reaching statistical significance (odds ratio, 3.76; 95% confidence interval, 0.92-15.41; P = .07).
The 5 × 4 mixed-model ANCOVA still showed a trend to statistically significant time*group interaction ( p = 0.07) and time*sex interaction ( p = 0.08), with no effect of nVAS ( p = 0.835), the amount of LTRs ( p = 0.61), or group*sex interaction ( p = 0.77) for changes in PPT.
FNDC5 z-scores also showed a trend of inverse association with pThr181-tau immunoreactivity in the hippocampus (Pearson r = −0.30; p = 0.07) ( Figure 2G ).
Furthermore, the highest of the specific IgE values at baseline to any of the foods in the participants’ OIT showed a trend to be important for the study outcome in the placebo arm (P = 0·07, FDR adjusted P = 0·19, appendix p 7), while this was not the case in the omalizumab arm.
PIK3CA -mutant PDX models showed a trend toward an improved response to alpelisib as well (one-tailed p = 0.07).