It was 0.757 (95%CI = 0.672–0.829) which was still significantly higher than that of HBV DNA (AUROC 0.604, 95%CI = 0.513–0.690; P = 0.013), and showed a trend to be better than those of LRM and qHBsAg level (AUROC 0.670, 95%CI = 0.581–0.751, P = 0.063; 0.670, 95%CI = 0.581–0.751, P = 0.063 respectively) ( Table 4 ).
Multivariable analysis further indicated that baseline PSA showed a trend toward being an independent predictor for achieving PSA ≤0.2 ng/mL (P=0.063).
This effect occurred because the intervention group scored significantly worse than the community group, p = 0.031, and the waitlist group showed a trend toward worse performance than the community group, p = 0.063.
Insertions/deletions (INDELs) were less common (98/1267 [7.7%]) than single nucleotide variants (SNVs) (1158/1267 [91.4%]) but showed a trend for higher incidence among discordant variants (Pearson’s p = 0.063); in this context, discordance concerned polyC stretches, as widely discussed for this technology.
While the univariate analysis showed a trend toward statistical significance (OR = 0.854; p = 0.063), the multivariate model indicated that PMI was an independent factor associated with a complicated disease course (OR = 0.655; p = 0.018).
ERN-LFPs were significantly more negative than CRN-LFPs bilaterally in P2 and P4 and showed a trend level difference in the right NAc in P1 (P1 right p = 0.063; P2 and P4 p >0.002; Table 3 ; Figure 3 ).
We observed that “R” exhibited higher concentration of HDL-C ( P = 0.031) and lower small HDL particle concentration ( P = 0.045) than “NR.” Although not significant, “R” showed a trend toward higher concentration of large HDL particles ( P = 0.063) and non-ABCA1 specific cholesterol efflux capacity ( P = 0.075) than “NR.” A positive linear correlation was observed between total CEC and HDL-C (r = 0.825; P = 0.003) and total HDL particle (r = 0.847; P = 0.002) for “R” ( Figure S5 ).
Similarly, the time to target showed a trend toward a decrease from block 1 to 3 (F 1,80 = 3.54, p = 0.063), but the incremental changes from block 1 to 2 and block 2 to 3 were not significant.
Participants following a long-term pattern with MDs showed significantly decreased plasma levels of MCP-1 ( p < 0.001, both), MIP-1β ( p < 0.031, both), ENA78 ( p < 0.001, both), IL-1β ( p < 0.025, both), IL-6 ( p < 0.013, both), IL-8 ( p < 0.025, both), IL-12p70 ( p = 0.022, MD-nuts), TNF-α ( p < 0.022, both), IFN-γ ( p < 0.040, both), and hs-CRP ( p < 0.018, both), while no significant changes were observed in these biomarkers in the LFD group ( p > 0.05), except for hs-CRP that showed a trend to reduction ( p = 0.063).
Exploratory post-hoc testing showed a trend towards improved MBP myelin alignment in the ischaemia-Epo group in the first parasagittal white matter [2-Factor ANOVA; F (1) = 3.761, P = 0.063], with no significant interaction between rEpo and hypothermia.
comparison), showed a trend for a positive relationship between serum ionized calcium and white matter lesion volume (β = 4.34, SE = 2.27, t = 1.91, p = 0.063).
These include socioeconomic status, number of pregnancies, a high carbohydrate diet, a low intake of vegetables, a low level of physical activity, history of obesity before the age of 18, and consumption of sweetened beverages (the latter was not statistically significant but showed a trend, with a p = 0.063).
Conversely, the Diagnostic Outcome Trial in Heart Failure (DOT-HF) trial 36 showed a trend toward higher risk of primary endpoint (ACM or hospitalization for CHF) (HR 1.52, 95% CI 0.97–2.37, log-rank p = 0.063) compared to the control group.
The olfactory bulb pitch showed a trend of being correlated to cranial width (Χ 2 (1, n = 12) = −0.55, p = 0.063).
Supplementation with casein showed a trend for increased alpha diversity compared to the protein-free diet ( p = 0.063); however, both the CP.H-based and CP-based diets had significantly increased alpha diversity at the end of the protocol.
All-cause 5-year mortality was associated with reduced miR-133 levels (HR: 0.09; 95% CI: 0.01, 0.86; p = 0.037) and showed a trend for the association with lower miR-223 levels (HR: 0.30; 95% CI: 0.08, 1.07; p = 0.063) (Table 2 ).
The CGI-S showed a trend toward improvement over placebo in the arbaclofen group ( p = 0.063) but this was the only measure showing a strong trend, and given the multiple comparisons, this result alone is difficult to interpret as meaningful.
Risk of recurrent cardiovascular events according to TNFi exposure In the univariable model of inverse probability weighted Cox regression analysis, TNFi exposure showed a trend toward a lower risk of recurrent cardiovascular events than TNFi non-exposure (HR 0.39, 95% CI 0.15–1.05, p = 0.063).
In a final model including basal insulin, gender and BMI (model 3), gender remained the only significant independent variable ( P =0.048), although BMI showed a trend toward affecting peak cortisol levels negatively ( P =0.063).
However, the worst performing sprinters (first tertile of physical performance) showed a trend for significant (p = 0.063) higher post-exercise urinary Cr levels compared to the most efficient sprinters (third tertile) ( Figure 4 ).
TAR also showed a trend toward protection in adjusted analysis (HR, 0.381, 95% CI, 0.138-1.053, P = .063).
Similarly, the Radiation Therapy Oncology Group (RTOG) #9501 trial showed a trend toward improved OS rates, albeit with marginal significance (OS rate of 42% with adjuvant CRT, compared to 31% with RT alone, p = 0.063).
PIU+ showed a trend toward reduced negative emotion between BL and WS3 ( p = 0.063) and significant self-esteem increases from BL to WS2 ( p = 0.043) and WS3 ( p = 0.042).
CTC presence correlated with older age (χ 2 = 5.006, p = 0.025), showed a trend toward association with metastasis (χ 2 = 3.452, p = 0.063), but no other clinical parameters.
Although C-ACT scores showed a trend towards improvement (baseline: 22.5, study end: 24, p = 0.063), no significant change in lung function was observed.