The prevalence of most comorbidities, including diabetes ( P = 0.526), kidney disease ( P = 0.287), and severe liver disease ( P = 0.875), was similar across trajectory patterns, while congestive heart failure showed a trend toward higher prevalence in trajectory 3 (30.0% vs. trajectory 1: 19.2% vs. trajectory 2: 21.9%; P = 0.058).
Specific correlations with clinical variables were observed in the FW group, where entries into CAP3 showed a trend-level correlation with duration of illness ( r = 0.36, P = 0.058), while entries into CAP2 significantly correlated with STAI-S scores ( r = −0.42, P = 0.02).
pre-confluent control) but showed a trend to improve with a CFE of 13.60±1.90% after one day of re-incubation (p = 0.058).
Antiplatelet therapy was associated with improved functional outcomes at discharge (odds ratio=1.405 [95% CI, 1.028–1.920]; P =0.033), and showed a trend towards reducing 1‐year mortality (odds ratio=0.395 [95% CI, 0.152–1.031]; P =0.058).
In the overall population, the group receiving OFS in the high CR-score (CR-score above 1.42) cohort showed a trend towards improved DFS compared to the non-OFS group ( p = 0.058, Fig. 4 A).
The Simpson (evenness of bacterial composition) indexes showed a trend (p=0.0581) of a decrease in diversity with increased SARS-CoV-2 severity.
muciniphila and GOS showed a trend ( p = 0.0581) towards fewer buried marbles, suggesting less impulsive or anxiety-induced behavior.
Interestingly, FS-Res animals spent more time in REM sleep than FS-Esc animals (p = 0.0261) and showed a trend toward increased REM sleep compared with FS-Frz animals (p = 0.0582) on day 14.
The sperm count showed a trend toward being related to the SDFI ( ρ = −0.25931; P = 0.05829).
orbifer (southern tip of Italian Peninsula) and specimens from the rest of Europe only showed a trend in the differences between the distances to their species barycentre (Kruskal–Wallis chi‐squared = 5.682, df = 2, p = .0583).
nNOS−/− mice treated with high nitrate showed a trend to increase XOR protein ( p = 0.0583, unpaired t -test), while nNOS−/− mice treated with low nitrate revealed a trend to increase sialin protein ( p = 0.0594, unpaired t -test).
This might explain why the overall analysis of the HNC patients with preexisting hyperlipidemia treated with statins only showed a trend toward a protective effect against anxiety/depression compared to the hyperlipidemia patients who did not use statins ( P = 0.0584).
DAT−/− rats showed a 1.5-fold increase in the levels of ALDH1L1 (one-way ANOVA F (2, 14) = 11.79; p = 0.0010; Tukey’s multiple comparison test p = 0.0007 DAT−/− versus DAT+/+ controls), while DAT+/− rats showed a trend toward elevation that did not reach statistical significance (Tukey’s multiple comparison test p = 0.0586 DAT+/− versus DAT+/+ controls; Figure 4 A).
During the subsequent dark phase (ZT 12–24), males showed a trend toward reduced wakefulness ( p = 0.0586) and increased NREM sleep ( p = 0.0567; Figures 2B , D ), suggesting a redistribution of vigilance states across the circadian cycle.
In contrast, E3 mice on a HFD treated with insulin showed a trend towards exploring the novel object more than the familiar object ( t = 1.756, p = 0.0586) (Fig. 2 F).
However, type III BNST DL neurons showed a trend toward TLS effect on spike frequency, p = 0.0586, F(1.383, 8.297) = 4.443, n = 7, 6 rats, and a current effect, p = 0.0088, F(1.051, 6.306) = 13.70, with no interaction, p = 0.1178, F(2.840, 17.04) = 2.286.
Besides, the APC gene mutation showed a trend ( P =0.0586) towards being associated with PFS, although it did not reach strict statistical significance.
The cumulative temperature increase, i.e., the actually recorded temperature over a 9-day period with normal circadian temperature pattern subtracted was significantly higher in the combined-route group than in the aerosol–BAL group ( p = 0.0085), while the difference with the aerosol group did not reach the threshold for significance but only showed a trend ( p = 0.0586).
Despite the absence of significant sex-related differences, the results showed a trend toward a higher percentage of effectiveness among female patients ( p = 0.0587).
Moreover, re‐induced CSD‐like traveling waves took significantly longer to propagate to the same ROIs (Figure 3A,F ; mPFC, p = 0.0005; SSp‐bfd, p < 0.0001, Figure S10B,C , Supporting Information), showed a trend toward slower propagation speeds in the cortex (mPFC, p = 0.0587; SSp‐bfd, p = 0.0549, Figure 3E,J ), and had an overall longer traveling duration.
MicroRNA-140-5p showed a trend to increased expression ( p = 0.0587) in OA cartilage compared to NOF as we have previously reported 8 ; the more highly expressed miR-140-3p showed no difference between groups.
The difference in median SIS showed a trend toward greater involvement in PLWH of 0.39 (−0.01 to 0.79, p=0.0589; I 2 =86%, p=0.001; figure 4 and online supplemental table 6 ) but also did not reach statistical significance.
Patients with high nutritional risk, as defined by the mNUTRIC score ( Table 7 and Figure 4 A), showed a trend toward reduced survival probability compared with those classified as low nutritional risk, approaching statistical significance (log-rank p = 0.059).
The ORR showed a trend toward a better benefit for RC48-ADC therapy in patients with HER2 amplification than in those without amplification (61.5% vs. 44.8%, P = 0.059).
The results also showed a trend toward survival benefit with remdesivir (mortality of 8% in remdesivir arm versus 11.6% in placebo, p =0.059).