Increased expression of Il6 ( P = 0.06) and Il17c ( P = 0.08) in these tumors in the HFD offspring reached borderline significance only ( Fig. 2A and B ).
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In the literature
There was a trend toward an increased risk of microalbuminuria in women that was not statistically significant in the unadjusted competing risks regression (SHR 1.18, 95% CI 0.99, 1.41), reached borderline significance in Model 1 (SHR 1.21, 95% CI 1.00, 1.46) and was not significant in Model 2 (SHR 1.20, 95% CI 0.99, 1.46).
Although the 8q24 rs10090154T allele confers a 1.7-fold increase in PCA risk in a small case-control study set involving African Americans (85 cases and 149 disease-free men), this locus only reached borderline significance (OR = 1.69; 0.92-3.11).
However, after controlling for other potential confounding factors, the difference of weaning for the both groups only reached borderline significance in both pre-PSM and post-PSM samples, indicating that the weaning rate was relatively lower for the tracheostomy group, but the difference was not very significant.
One study that did report an adverse effect looked at US male veterans and showed that those living within 50 m of major roads had a increased risk of persistent wheeze, with a significant odds ratio of 1.7 for heavily trafficked roads (> = 10,000 vehicles a day), but a smaller effect (OR = 1.3) which reached borderline significance when all major roads were considered[ 1 ].
The bivariate LODs for LV wall thickness factor with BMI in both minimally and maximally adjusted models reached borderline significance at the genome-wide level.
However, at the CpG-unit level, the difference was significant, or only reached borderline significance, at six of the 15 CpG units scored ( Fig. 4 ).
Between-arm differences in weight and BMI over the study period reached borderline significance.
1.4%, p = 0.11), but only reached borderline significance.
The median percentage of Ki-67+CD4+ T cells in chronic progressive patients was significantly higher than in chronic stable patients at baseline and second follow-up, and reached borderline significance at first follow-up.
It was reported that wearing reading glasses correlated significantly with high mini-mental state examination for the visually impaired (MMSE-blind) after adjustment for sex and age (OR = 2.14, 95% CI = 1.16–3.97, p = 0.016), but reached borderline significance after adjustment for education [ 91 ].
In this regard, it should be noted that although body weight and BMI reached borderline significance, these reductions were modest (from 68.9±13.3 kg to 68.1±13.2 kg, and from 28.4±5.0 kg/m 2 to 27.9±4.8 kg/m 2 , respectively), and with small effect sizes (0.05 and 0.09, respectively), while the reduction in WC was more compelling ( P <0.001) and with larger effect size (from 98.3±13.2 cm to 94.6±12.6 cm; effect size =0.30).
Comparing the association between social loneliness and mental HR-QoL [std-β: −1.84; 95%-CI: −2.27 to −1.41] with that between social loneliness and physical HR-QoL [std-β: −0.95; 95%-CI: −1.44 to −0.45] reached borderline significance.
The weekly frequency of day napping as well as meeting the sleep recommendations during week-days also reached borderline significance in boys, but not in girls.
A low PaO 2 /FiO 2 ratio was a significant mortality predictor in both groups, while HF was a significant mortality predictor in non-CCS patients and reached borderline significance only in CCS patients.
In EASs, while the inverse association between CAD and MDD reached borderline significance in the primary IVW analysis, neither MR‐Egger nor weighted median methods produced significant estimates, and confidence intervals were wide.
At the level of species within orders, however, we found a negative relationship that reached borderline significance: species from smaller orders tended to have a higher mean research effort than species from larger orders (Spearman rho between the number of species per order and the average number of publications per species within each order = −0.354, p = 0.055, Figure 2b ).
With the use of protons, patient-reported bowel-score according to EORTC QLQ-PR25 questionnaire was already improved at week 10 and reached borderline significance when compared to photon therapy [ data unpublished ].
Although there was no difference in bacterial metabolite levels between the patients and controls for LA and PA, these metabolites alone reached borderline significance and had an interesting effect size on the microbial structure (6.5% and 8%, respectively).
Of the health measures (Model 2e), functional somatic symptoms was significant in women while in men, only behavioral symptoms reached borderline significance.
Although the primary outcome reached borderline significance, a post hoc analysis adjusted to the dose of intravenous furosemide showed a statistically significant result, which is consistent with the hypothesis of synergy when adding HCTZ to furosemide, with a clinically relevant effect on daily weight loss.
In the Stockholm 2 cohort, the correlation between S6K2 and/or 4EBP1 and high S-phase fraction reached borderline significance.
However, the analysis only reached borderline significance after FDR correction (pFDR = 0.063).
For early treatment versus none, highly consistent, protective point estimates were also generated for most comparisons in adults and children, but failed to reach a statistical significance for IRP [possibly due to type II errors (sample size) although they reached borderline significance for ‘any pneumonia’ (all cases)].
[ 21 ], positive effects of levodopa and the dopamine D2 receptor agonist bromocriptine on serial ordering performance only reached borderline significance (also see [ 22 ]).