“nominally significant”

In the KEGG pathway analysis 17 pathways were nominally significant but none passed the threshold of an FDR-corrected p-value < 0.05.

Although no PTMs were significant after adjusting for multiple testing, several PTMs, such as pT69, pT212, and pS214, were nominally significant at p < 0.05 (Fig. 3 and Table 4 ).

We evaluated how well independent pQTLs reported by the INTERVAL study 9 ( n = 3301) replicated in our results and found 75.6% to be both directionally consistent and nominally significant ( P < 0.05) (Supplementary Note 2 and Supplementary Figs. 6 and 7 ).

Using a nominally significant cutoff ( p < 0.05), 30 module-trait relationships emerge, with a range from zero to six significantly correlated modules per trait.

For any medication with a nominally significant association ( p < .05), the same analysis was repeated in the chemotherapy group to test for nonspecific effects.

A total of 19 HLA alleles had nominally significant maternal and/or fetal effects on BW ( P <0.05; Supplementary Table S7 , available as Supplementary data at IJE online); 13 of the 19 alleles had evidence for a maternal effect only, four alleles primarily had evidence for a fetal effect only and two alleles had evidence of both.

Raw P < 0.05 was considered nominally significant, whereas FDR-adjusted P < 0.05 was considered significant after correction for multiple comparisons.

We selectively included 44 diseases (excluding cancer, which is a limitation to be noted) in the first part of phenome-wide association analysis (PheWAS) and identified nominally significant associations ( P < 0.05) between the SES-associated variants and CHD.

We retained for downstream analyses all loci with nominally significant binomial p values ( p < 0.05) and at least 2 reads (10%) mapped to any allele.

The 36 nominally significant miRNAs ( p < 0.05) identified in the PDN/PDD comparison from LIMMA were used to classify disease state (See Figure 2B ), though with more limited accuracy than the PD-control model (absolute error rate = 13.8%, sensitivity = 81.2%, specificity = 88.9%).

To obtain stringent TFBS predictions, an empirical score distribution was estimated for each PWM for each species' genome as the set of all nominally significant ( P < 0.05) motif scores identified within the target set of promoter sequences [pwm_scan -s 1 -p ln(0.05)].

They first extracted nominally significant signals ( p <0.05) from three GWAS studies (WTCCC, German, and NIMH GAIN datasets; Fangerau et al., 2004 ; Wellcome Trust Case Control Consortium, 2007 ; Baum et al., 2008 ), and prioritized potential candidates based on independent, converging lines of evidence from various bioinformatics resources.

While no effect differences were significant at Bonferroni-corrected p -value thresholds, we observed 35, 31, and 8 nominally significant ( p < 0.05) effect differences for Blacks compared to Whites for hospitalization ( Figure S4 ), ICU/admission ( Figure S5 ), and death ( Figure S6 ), respectively.

Of these, five showed nominally significant ( p < 0.05) association with MS ( Figure 1 , Table 2 ).

It should be noted, however, that due to a low number of mutations, especially in the hotspots, the analysis is of relatively low statistical power, and most results are only nominally significant (Mann-Whitney or t-test, p<0.05; Supplementary Table S9), resulting in a relatively low number of miRNAs associated with the mutations in their genes.

Fisher-Irwin exact tests of association determine the best possible mode of genetic effect at a nominally significant p-value < 0.05.

Here, we restricted the GRSs to index variants from the previous study 21 that were not only GWAS significant for at least one trait, but also nominally significant ( p -value < 0.05) for the remaining traits.

No significant group differences in BMI trajectories during the pandemic were observed (F(2,392) = 0.43; P = 0.65, η p 2 = 0.002); a nominally significant increase in BMI was observed in the participants at low risk for eating disorder (pre-PD < LD2, P < 0.05) but not in those with higher eating disorder risk ( Fig. 5(d) ).

AG), and there was a nominally significant difference between the two groups with respect to log-additive model ( P < 0.05, Table 3 ).

The associations of 4 cytokines, namely, IL-1ra, beta-nerve growth factor (bNGF), stem cell factor (SCF) and macrophage colony-stimulating factor (MCSF), with sepsis outcome pairs were nominally significant ( P < 0.05) (Figure S1 ).

Proteins significantly associated with hippocampal volume and WMHs Using partial Spearman correlation, we found nominally significant associations ( P < .05) between 377 proteins and hippocampal volume in all individuals.

However, a few nominally significant associations are noticeable: Attention deficit hyperactivity disorder (ADHD) showed the most correlated UDIPs (44 UDIPs) ( p < 0.05) with absolute maximum genetic correlation value of 0.1811 ( p = 0.0003).

For associations with infections, we visualized the results of all allelic associations which had at least nominally significant p-values (P ≤ 0.05) with at least one infection category or with the “any infection” phenotype.

Out of 14 shared knowns that had genome-wide significant associations in OE, 7 had nominally significant ( p < 0.05) and directionally consistent associations in MCDS.

By fitting a linear mixed-effects model, we identified a total of 497 genes with nominally significant difference (p< 0.05) in viral infection response between asthmatic and non-asthmatic groups ( S6 Dataset ).