In addition, the pregnant women carrying the T allele of LPIN1 rs1050800 had a nominally significant 1.169‐fold risk of GDM (95% CI 1.000–1.354, P = 0.049) after adjustment for age compared with the women harboring the C allele.
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Among 21 candidate variants including genes in the interferon response pathway, APOE , TMPRSS2 , TLR3 , the HLA complex and the ABO blood group, only rs1205, a 3’ untranslated region variant in the CRP gene, showed nominally significant association in T-dominant model analyses (odds ratio 1.859, 95%CI 1.001–3.453, p = 0.049) after adjustment for age, sex, center, body mass index, and a history of cardiovascular disease.
A nominally significant difference in the direction of the preterm preadolescents outperforming the term preadolescents was detected only on Block Construction (F (1,37) = 4.131, p = 0.049), not surviving correction for multiple comparisons.
Unadjusted means favored both support groups (control: 5.79; call: 6.57; SMS: 6.80); the prespecified SMS-vs-control contrast was nominally significant ( P =.049, small effect).
For the participants with past history of COVID-19, there was a nominally significant increase in GMT at 21-days after second dose (p = 0.049) compared to 21-days after first dose (baseline value), and no significant difference noted compared to baseline value at 3-months (p = 0.26) and 6-months (p = 0.15) after the second dose.
Only the Body and Scar domain in the 8–17 year child self-report showed a nominally significant difference (0.72 vs. 0.42, p = 0.049, Cohen's d = 0.56), but this did not survive Bonferroni correction for five simultaneous comparisons (adjusted threshold p < 0.01).
We identified seven outliers in the analysis of SmkInit and CD risk using the MR-PRESSO approach and the causal association became nominally significant after removing these outliers (beta=0.13, P = 0.049, Supplementary Table 3 ).
MSH3 expression was not significantly associated with somatic expansion ( P = 0.625), whereas the association of DHFR expression, while nominally significant ( P = 0.049), did not survive correction for the number of phenotypes tested.
In the multiple regression model with each predictor adjusted for the others, the only nominally significant association ( P = 0.049) was between the number of researchers per 1 M and number of cases ( Table 1 ).
UPPS‐Lack of Premeditation with an optimal cut‐off of >8 was nominally significant ( P = 0.049), but was associated with exceedingly low sensitivity and NPV (0.24, 0.52, respectively) and classified AUD status with only 56% accuracy.
In the skull EEG, there was an insignificant decrease in ITC at 40 Hz (t (10) =2.108, P =.061) and a nominally significant increase in ITC at 20-Hz stimulation (t (10) =2.237, P =.049).
Interaction analysis indicated a nominally significant interaction between αT/(TCH+TG) and sex in relation to TgAb levels ( p = 0.049).
A nominally significant association of DCTN1 PDVs with PD was found in the EoPD & FPD cohort (20 vs. 7, p = 0.049), which did not remain significant after correction (FDR p * = 0.098).
The comparison of allele frequencies between the responder and nonresponder groups revealed a nominally significant difference for the rs235770 polymorphism ( p = 0.049).
non-US subgroups was nominally significant ( p = 0.049), although this result was not corrected for multiple comparisons.
The only nominally significant between‐group difference was for FNAE ( p = .049), but this was in the opposite direction to that expected under a simple dosage‐effect expectation, with greater improvement observed in the lower‐engagement group.
Logistic regression in Table 3 showed that rs6458093 was associated with an approximately 1.54-fold increased risk of GDM under the dominant model ( p = 0.044), and this effect remained nominally significant after adjusting for age, first-trimester BMI and systolic blood pressure ( p = 0.049).
Males had slightly more affected organ systems than females, although this was only nominally significant (mean and ranges: 3.55 [1–12] for males, 3.49 [1–11] for females; linear regression p = 0.049; Supplementary Fig. 1 ).
The association between stimulant use and DRD2 was nominally significant (at the 0.05 level) before correcting for multiple testing ( χ 1 2 =3.88, P =0.049, β =−0.18).
We identified nominally significant positive GxE effects in the full cohort ( R 2 = 0.08%, p = 0.049) and in women ( R 2 = 0.19%, p = 0.017), but not in men ( R 2 = 0.15%, p = 0.07).
For CSF pTau181, a nominally significant median change from baseline of −19.6 %, ( p = 0.049, Fig. 2 and Supplemental Tables 6 and 7) was measured in the 60 mg/kg Q4W sabirnetug-treated participants versus the placebo-treated participants, which showed an increase.
However, this difference was only nominally significant (p = 0.049).
increased exon inclusion) in heat call-treated embryos, with the enrichment analysis showing a nominally significant difference (proportion of gains=0.24, P =0.049, q =0.34; total exon skipping events=17) ( Table S5 ).
Results A nominally significant association with breast cancer risk was observed for MTHFR C677T polymorphism heterozygous genotype in the codominant model (OR: 0.57, 95% CI: 0.32–1.00, p = 0.049) and for Cys/Cys genotype of the OGG1 Ser326Cys polymorphism in the recessive model (OR: 0.23, 95% CI: 0.05–1.11, p = 0.0465).
The TDT identified one nominally significant association (p = 0.049) with intragenic marker rs7193756 (chr16:29,657,155-29,657,655) from the Affymetrix 5.0 data; however, the DFAM was not significant (p = 0.20) ( Table S1 ).