“nominally significant”

We found a nominally significant association for the PGS for LA PEF with an effect direction consistent with that of ischemic stroke (HR per SD increase, 0.94 [95% CI, 0.88–1.00]; P =0.049).

1 C); with a nominally significant increase in the non-delirious group (median increase of 11.4%, 95% CI: 0.0%–23.5%, p = 0.0491).

There was a nominally significant association between the s allele of the 5-HTTLPR polymorphism and TEM (odds ratio, 1.434; 95% confidence interval, 1.001–2.055; P = 0.0493; I 2 = 52%).

In uncorrected pairwise comparisons, only the proportion of activated NK cells showed a nominally significant difference between the IDD and control groups (raw P = 0.04949).

Additionally, there was a nonsignificant trend towards multiple repeat mutations (p = 0.5127), as well as, a nominally significant trend towards deletion mutations (p = 0.0495) (Table 6 ).

A nominally significant association with BPD was found for rs1006737 in CACNA1C ( P =0.0498).

Finally, we found significant differences in the frequencies of TAGA ( P = 0.005, OR = 3.187, 95% CI 1.376–7.382) containing rs4570625-rs11178997-rs1386494-rs7305115 between ODD and control groups (Tables 7 , 8 ). However, the further analysis by Haploview revealed the nominally significant finding for rs1386494 ( χ 2 = 3.846, P = 0.0499), and only one haplotypes (TAGA, χ 2 = 4.366, P = 0.0367) remained significant.

Genome-wide differential expression analysis between medicated and non-medicated samples in each lesion subtype resulted in 569 (DIE), 836 (OMA) and 638 (SUP) nominally significant genes ( p < 0.05).

We considered that either condition was nominally significant if the confidence interval of the average causal mediated effect did not intersect zero, and had an associated P < 0.05 ÷ 2 (correcting for the two conditions).

We then performed a pathway enrichment analysis on all 353 nominally significant ( p < 0.05) genes from the burden test (i.e., CVM-associated genes).

In the Results, we present nominally significant results ( P < 0.05) results with a Bonferroni correction for the number of SNPs being analyzed ( α /2; P < 0.025), which was consistent with the approach used in a prior study assessing genetic variants and GxEs as predictors of mental health trajectories (Latendresse et al. 2011 ).

We did not identify any metabolites significantly related in the meta-analysis to any of the four traits (FDR < 0.05) where there was even a nominally significant association (uncorrected P < 0.05) in African-Americans where the effect estimate was in the opposite direction. 3.

Evidence of 22 (51%) non‐genetic biomarkers exhibited a nominally significant effect ( p < 0.05) on AS, and 7 associations (14%) showed small‐study effects.

Additional nominally significant (i.e., p < .05) three-way interactions for CD and emotional difficulties are presented in supplemental Figure S1.

Of the remaining eight risk SNPs without significant signals, they found nine genes among four SNPs that were at least nominally significant ( P <0.05).

In the database we store all nominally significant dependencies (p<0.05) with a CLES ≥ 0.65.

Through Model 1, there was a tendency towards a positive association between birth weight PGS and plasma levels of 5 proteins FABP2 (fatty acid-binding protein, intestinal), LPL, TNF (tumour necrosis factor), TNFB (TNF beta), GIF (gastric intrinsic factor) and a negative association with 3 proteins PRSS8 (prostasin), KIM1 (hepatitis A virus cellular receptor 1), and AMBP (protein AMBP), which were nominally significant ( P < 0.05) ( Fig. 3 b; Supplementary Table S10 ).

2 ; Supplementary Figures 1 , 2 ), and a nominally significant p-value (unadjusted p-value < 0.05) was used to define FSCV DEGs in these signatures.

Meanwhile, when covariates were included, 7,350 genes were nominally significant (p < 0.05), and 5,532 genes remained significant after multiple comparison correction (padj < 0.05).

In contrast, just one scale showed a nominally significant ( p < 0.05 uncorrected) greater proportion of individuals with severely elevated scores in XXY/KS as compared to XYY: emotional problems on the SDQ.

We declare h g 2 >0 to be nominally significant (P<0.05) if h g 2 is larger than each value analogously estimated from 19 data sets with sample labels randomly permuted (thus, 5% of genes will be nominally significant even in the absence of a true effect).

Five SNPs within this region are nominally significant at p -value < 0.05.

3.3 Univariate linear regression analysis Among the 831 features investigated, 42 showed a nominally significant difference at a p = .05 level between the n-3 LCPUFA supplementation and the placebo group.

For this reason, we present both sets of results, noting that nominally significant results ( p < 0.05) should be interpreted cautiously.

Very little epistasis was apparentin the hotspot regions, with less than 7% of trans methQTL in these hotspots possessing a nominally significant (P<0.05) epistatic interaction, and less than 1%of trans methQTLwith a significant epistatic interaction(see Supplementary Table 3 ).