At the subcortical level, a nominally significant uncorrected effect was observed for HC versus ET in the left thalamus ( p = 0.04, uncorrected, t = −2.07), with sub-threshold trend-level uncorrected effects in HC versus LTG ( p = 0.12, uncorrected, t = −1.58) and HC versus HTG ( p = 0.06, uncorrected, t = −1.91).
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There was a nominally significant association with cardiovascular events after adjustment for 10 cardiovascular risk factors (Model B) (HR 1.27, 95% CI 1.01–1.59; p = 0.04).
Although nominally significant ( P = 0.04; see Table S1 ), the likelihood ratio test applied makes an assumption of residual normality that is clearly violated as this is a binary trait.
Although there was no significant relationship between exercise intervention and mtDNA-CN change (P = 0.29), there was a nominally significant association between mtDNA-CN and metabolic syndrome (P = 0.04), which has been seen in previous literature.
The m.16390G>A variant was also found to be more common in type 2 diabetes cases than in controls in a Tunisian study population, but the nominally significant association (p=0.04) did not survive multivariate regression analysis [ 47 ].
A post hoc analysis checking for sex interactions across the factors revealed a nominally significant interaction with sex for cardiometabolic MR1 only (GHQ-12 beta = −0.075, p = 0.040, SF12-MCS beta = −0.075, p = 0.042, reference category female).
The ABC showed a nominally significant reduction in the hyperactivity subscale, but only at week 2 ( p = 0.04) and lethargy at week 4 ( p = 0.04), although large effect sizes were again seen in the majority of the ABC subscales at some time points ( Table 4 ).
MiR‐223‐3p showed a significant AUEC over 0.67 days for IFNβ‐1a when the miRNA returned to baseline ( p = 0.015), and a nominally significant AUEC for pegIFNβ‐1a over 13 days ( p = 0.04).
In a meta-analysis of the two cohorts, the ACE polymorphism remained nominally significant ( P = 0.04).
The evidence for three populations rather than two is nominally significant as shown in the formal likelihood ratio tests ( p = 0.04; Fig. 2 c).
The FXS diagnostic grouping produced nominally significant effects on frontal (F = 4.46, P = 0.04) and temporal GM volumes (F = 3.86, P = 0.05): individuals with FXS had smaller volumes of these structures than individuals with idiopathic autism.
The GABA gene set showed nominally significant association with inhibition ( P =0.04), but this did not survive correction for multiple comparisons.
Effect Modification by Sex, Smoking, Diabetes, and Genetic Factors In UKB, we observed a nominally significant interaction between caffeine intake and smoking status for incident clinical all‐cause dementia (nonlinear interaction p = 0.04).
Similarly, epistasis of olfactory behaviour was not significantly correlated with epistasis for day sleep and night sleep for Crc , and the correlation with waking activity in males was only nominally significant ( P= 0·04; Fig. 6 ).
When examining all subjects, nominally significant associations between carrier-status and remission (p = 0.04) and PSS-14 scores (p = 0.04) were observed after correcting for treatment arm.
We noted a borderline nominally significant interaction with sex, suggesting a greater risk among women with the chromosome 9p21 risk allele, for subsequent CHD death/MI (interaction P value = 0.04), whereas nonsignificant trends were noted for greater risk in those without hypertension ( P value=0.08) or without renal impairment ( P value=0.17).
While evacetrapib did not demonstrate overall major adverse CVD events (MACE) reduction at 26 months, there were no significant safety signals, and a nominally significant ( P = 0.04) reduction in total mortality was observed. 6.4 Anacetrapib The most recent CETP inhibitor tested in clinical trials was anacetrapib.
In a previous meta-analysis, the pooled OR derived from nine case–control studies is nominally significant (random-effects pooled OR = 1.07, P = 0.04), while the pooled OR derived from five family-based studies increases notably to an OR of 1.54 (P = 0.000019).
This association was nominally significant ( p = 0.04) in the Spanish cohort ( Mancama et al., 2007 ).
99 When the SF36 physical summary score data were analyzed by multivariate testing taking baseline scores into account, the authors reported a nominally significant difference ( p = 0.04) favoring zoledronic acid, but this was not adjusted for multiple comparisons.
However, logistic regression under the co-dominant model revealed a nominally significant association for the AG genotype (OR = 2.76, 95% CI: 1.01–7.5, p = 0.04; AIC = 144.0, BIC = 158.1), while no significant association was observed under the dominant model (OR = 2.30, 95% CI: 0.95–5.6, p = 0.06).
In the first of these studies, the benefit of the hypnotic for depression was not significant at week 4 after the investigators removed the rating scale items related to insomnia, whereas the week 8 benefit was nominally significant only at the P=0.04 level not correcting for multiple comparisons.
However, the A allele showed a nominally significant association with increased eGFR ( p = 0.04, β = 0.026) within the discovery set (ESM Table 7 ).
CAV1, PDPN, and ZFPM2 also demonstrated nominally significant differences across specific age group comparisons (p ≤ 0.040), though their patterns were comparatively less consistent.
and X2 P=0.02 respectively).” “However, analyzing each variant separately revealed that the p.V443I variant occurred at higher frequency in AHM cases (4.44%) compared to PM cases (1.57%), BNMS controls (0.84%), or the MGRB (1.09%) (combined control comparison X2 P=.01), with comparison of any case nominally significant (X2 unadjusted P=0.04).” “Most significantly, the rs7174027*A SNP flanking the OCA2 gene promoter region/transcription start site was absent in AHM patients, compared to a frequency of 7.1% in the PM group (X2 unadjusted P=0.0005) and 9.43% frequency in the BNMS control group (X2 unadjusted P=8x10-5).” Supplementary materials have track changes and highlight marks that need to be removed.