“nominally significant”

Univariate post-hoc tests showed that this effect was mostly driven by IL8, which was the only marker showing a nominally significant association with group ( F (1, 106) = 5.047, p = .027, η p 2 = 0.045), with a small to medium effect size.

Post hoc tests for each picture valence category separately revealed that the HC-yes group recalled significantly more positive pictures ( t (2167) = −3.78, p = 0.0002, d = −0.16) and nominally significant more negative pictures ( t (2167) = −2.22, p = 0.027, d = −0.10) in the memory task compared to the HC-no group.

We note that MAPT is only nominally significant in the PWAS of clinical AD ( p = 0.027, FDR = 0.52), perhaps due to power limitation, and future larger GWAS may help resolve this.

MR analyses showed a nominally significant causal effect of WHRadjBMI on pancreatic cancer (OR[95%CI] = 1.00095[1.00011–1.0018], P = 0.027) but not for BMI on pancreatic cancer.

IgM had an estimate similar to that previously stated (β=−0.232) and showed a nominally significant p -value ( p = 0.027).

We also identified a nominally significant effect for ER-positive breast cancer (OR = 2.16 [95% CI, 1.09-4.26], P = 0.027).

We observed a nominally significant enrichment in genes overlapping regions near common variants associated with schizophrenia 24 (OR=1.37; 95% CI=1.09–1.73; P = 0.027) ( Fig. 2 ) hinting at some degree of convergence.

In sensitivity analyses excluding variants from each gene region in turn ( appendix p 20 ), the association with all-cause mortality in the deficient stratum was attenuated, but remained nominally significant when excluding variants in the CYP2R1 gene region from the analysis (OR 0·80 [95% CI 0·66–0·98]; p=0·027).

When PRS calculation was restricted to BD variants with genome-wide significance ( p -value threshold 5×10 −8 ), the PRS of BD cases from the two Cuban families showed a nominally significant increase compared to the PRS of family members with no psychiatric disorder or a non-BD psychiatric phenotype ( p = 0.027, S2B Fig ).

However, a few of its linkage disequilibrium (LD) proxies (r 2 > 0.77 in Europeans) were nominally significant in the meta-analysis (results for the leading variant rs9271588, OR [95% CI] = 1.20 [1.02–1.41], p = 0.027).

Analysis of rare variants by optimal sequence kernel association (SKAT-O) test showed a nominally significant difference in variant burden between the male PD patients and controls (2.01 vs. 1.38%, p = 0.027).

In single marker tests of the SNPs that make up the risk score, we found a nominally significant association with rs943080 in VEGFA within the AREDS dataset ( P = 0.028; Table 2 ); this does not replicate in the CWRU/HIHG dataset.

When tested for enrichment in 10 other GWAS datasets, SATB2_Hipp only showed two nominally significant enrichments (for ASD (P = 0.028) and CAD (P = 0.040) but these did not survive multiple test correction ( S4 Fig ).

Results We report a finding of a nominally significant result using the pedigree-based association test approach (PBAT; p = 0.028), while other family-based tests were non-significant, but with a p-value <; 0.10 in each instance.

Nominally significant positive associations were observed between I/Cr at 12 weeks and birth length and head circumference z ‐scores ( p = 0.028 and p = 0.005, respectively).

Out of the nine probes at which Noor and colleagues found an association between cord blood DNA methylation and paternal periconceptional BMI, only one showed a nominally significant association in consistent effect direction in the sperm obesity EWAS ( P = 0.028, DNA methylation difference = 6%) and the combined mixed effects model in blood and sperm ( P = 0.01, DNA methylation difference = 4%).

The initial marker SNP (rs3106653) examined in our prior GWAS in the Japanese population also showed nominally significant association in the Chinese population ( P = 0.028).

They found nominally significant allelic association in case of the catechol-O-methyltransferase rs362204 -/G ( P =0.028) marker, nominally significant genotypic associations for tyrosine hydroxylase rs6356 A/G ( P =0.04) and dopamine beta-hydroxylase rs1108580 A/G ( P =0.025) following the case-control approach.

IGF1 showed a nominally significant positive correlation with longevity (LDSC: rg = 0.06, P = 0.028).

Furthermore, primary lung cancer patients demonstrated a nominally significant increased odds of having made a serious smoking quit attempt compared to both MSC-1 and LSC-1 controls, with odds ratios of 1.44 (p = 0.028) and 1.42 (p = 0.026), respectively.

There was no clear association between HDAC9 and aneurysmal disease, but there was a nominally significant protective association with diastolic blood pressure (p = 0.028).

Additionally, we obtained two nominally significant SNPs (rs10760581, p = 0.0280; rs941960, p = 0.0280) in KYAT1 (which encodes Kynurenine Aminotransferase 1) in the full-model association tests with recessive modes of inheritance.

1A ) although only nominally significant with the total hip BMD measure (p = 0.028).

The parameter estimate associated with the interaction term was nominally significant (-0.13 ± 0.06, P = 0.028), suggesting that the joint effect of risk variants at the two variants was not linear.

Oxygen saturation showed nominally significant differences during 1 min (with WBVT: 92±3%; without WBVT: 91±3%; p=0.028) and 2 min of exercise (with WBVT: 91±3%; without WBVT: 90±3%; p=0.024), though these differences are not clinically relevant [ 14 ].