“nominally significant”

In the rivaroxaban 10‐mg stratum, there was a nominally significant lower incidence of symptomatic VTE in the age ≥75 group with rivaroxaban compared with placebo: 0.1% and 0.7% respectively, HR 0.11, 95% CI 0.01‐0.86; the interaction p ‐value for age group was .20.

An examination of the association structure around these genes in the GWAS summary statistics yielded nominally significant genetic support for the loci harboring CTNND1 and PRTG (Fig S2 C/D).

Assessment of enrichment of gene ontology terms for gene expression patterns with nominally significant p values for each of the three phenotypes showed enrichment in several signaling pathways.

Similar to the PAGE consortium, previous studies have reported nominally significant associations for fasting glucose at the MTNR1B , G6PC2 , and GCK loci in Hispanic Americans [ 24 , 26 ], and at GCKR in East Asians [ 27 ].

In the absence of a unified baseline risk denominator and detailed case definitions (e.g., acute vs chronic or tendon body vs attachment point types), this study cautiously interprets the estimate as a nominally significant, directionally consistent, weak-to-moderate effect.

Of these 22 metabolites, five were nominally significant, which were all already identified in the regressions on the metabolite concentration trajectories.

Finding only nominally significant enrichments in non-neuronal cell lines suggests these may be neuron-specific drug responses.

Moreover, we applied outlier-correction using Q-based statistics 92 when nominally significant excess heterogeneity as measured by the Q-statistic was detected.

Inspection of results within individual datasets revealed 28/540 (5.2%) of the comparisons were nominally significant (see Additional file 5 : Table S1) which is almost exactly the number of results expected to attain this level of significance due to chance alone.

Although multiple linear regression analyses revealed nominally significant associations between hearing group and cortical volume in certain brain regions, none of these findings survived correction for multiple comparisons using the FDR method.

We next performed a within-trio analysis, quantifying the difference in PGS liability between a proband and each of their parents and compared this quantity with repeated random sampling from nominally significant PGS with matching direction of effect and not linked to proband VUS HPOs (N permutations = 10,000; median PGS per proband = 168).

We noted a nominally significant treatment-by–baseline eGFR interaction for the effect of empagliflozin on the eGFR slope, which was apparent irrespective of whether the analysis categorized patients into 2 or 5 eGFR subgroups.

There were nominally significant associations found between specific SNPs and sperm ultrastructural characteristics, but these were not significant after Bonferroni correction for multiple testing.

Furthermore, because the difference was only nominally significant it would not have survived correction for multiple comparisons.

In the current analysis, the timing of treatment onset was determined by finding the first day from which a treatment effect was nominally significant and sustained without interruption through the end of the first dosing interval (week 12).

Multiple testing was controlled by adjusting for the total number of CpG loci tested, and a false discovery rate–adjusted P value (ie, q value) of <0.2 was considered nominally significant.

Although 23 SNP pairs were identified as nominally significant (Supplemental Table S5 ), no SNP pair survived for multiple comparison corrections.

10 was nominally significant (cg26930596) in one of our samples, but with an effect estimate in the opposite direction.

Of these, four probesets (corresponding to four unique genes) were nominally significant.

One to six additional peaks of smaller height are observed depending on the marker density; some of them had nominally significant p -values (Table 1 ).

Among individuals suffering from CD, we only observed nominally significant correlations with subject age (Bray-Curtis) and the average time spent outside (sunlight hours; Jaccard and Jaccard PICRUSt; Table S8 and S9 ), but no effect of other patient characteristics.

Group (Fisher exact test: p = 0.0061, OR = 0.24, 95% CI = 0.086 - 0.671), although this difference was only nominally significant ( Figure 4E ).

In addition, several other SNPs across the gene displayed nominally significant transmission distortion in a Chinese cohort ( Supplementary Table 2 ).

P-values ≤ 0.05 were considered nominally significant.

However, none of these candidate genes (14 for the ALMS1 -NAC and 6 for the HPS1 -TMA association pair) produced a pseudospectrum containing even a single nominally significant signal pointing to these metabolites (data not shown).