“nominally significant”

However the result for rs3748816 remains nominally significant even if corrected for the number of tests performed in the original screen.

In total, 726 unique lnc-eGenes whose eQTLs in liver are colocalized with at least one nominally significant GWAS SNPs (single nucleotide polymorphisms) were identified (Supplementary Data 1 ), suggesting their expression in liver are potentially associated with cardiometabolic traits.

A 12-week, Phase 3, DBRCT involving patients with OFF episodes despite stable anti-PD treatment evaluated sublingual apomorphine (dose range of 10–30 mg) and reported significantly greater self-rated full ON response within 30 min versus placebo, corroborated by a nominally significant full ON response using home-dosing diaries.

In this combined population, a nominally significant improvement from baseline was observed for the cipaglucosidase alfa plus miglustat group for Hex4 and CK levels, manual muscle test (MMT), and 6-min walk distance (6MWD), while a nominally significant worsening from baseline was observed for the alglucosidase alfa plus placebo group for CK levels, Gower’s Maneuver, Stairs, Gait, Chair (GSCG), and forced vital capacity (FVC; Figure 13 ) ( 55 ).

, − Three component metabolites defining this pathway, phenylpyruvic acid, phenylalanine, tyrosine, were found nominally significant in their associations with blood arsenic species, and phenylalanine was significantly associated with urinary %InAs after FDR correction.

In contrast, 10 markers were significantly associated with response to Pembro in HR + HER2 − tumors, with an additional 9 nominally significant markers.

These correlations were nominally significant, that is, did not survive multiple comparison correction, but persisted across NS thr .

Nominally significant association was observed in eight for rs6897932, in nine for rs12722489, and in 13 for rs2104286.

In the present study, exploratory treatment-by-time analyses revealed nominally significant differences in nodal degree and nodal efficiency of the left parahippocampal gyrus between the treatment groups.

The examination of a JAK2 V617F -CH cohort replicated associations with the 46/1 haplotype, TERT , SH2B3 and TET2 with nominally significant signals for CHEK2 , ATM , PINT and GFI1B 79 ; additionally, KPNA4 has been associated with a greater risk of all CHIP, inclusive of JAK2 -CH 27 .

Across probed models and across single cohorts, the nominally significant voxels were widespread throughout the brain, including the cerebellum, temporal and frontal areas, subcortical areas and somatosensory cortices.

Correlation between differential metabolites and clinical migraine symptoms Spearman correlation analysis of 211 DEMs identified 32 venous plasma metabolites showing nominally significant associations with migraine severity metrics (VAS, VRS, or HIT-6) within the PFO-M cohort.

As shown in sTable 3 , only one eicosanoid (299.25921/5.5) was nominally significant for women, but all were significant in men.

The 12 decline-associated variants were enriched for directionally consistent nominally significant association with rapid decline and eGFR-decline in CKD ( P enrich =1.6 × 10 − 8 or 2.2 × 10 −3 , respectively), but the 11 stable-effect variants were not ( P enrich = 1.0 or 0.43, respectively; Fig. 3b and Supplementary Table 6 ).

Hazard ratio (HR), odds ratios (OR) and 95% confidence intervals estimated the associations for which a P value less than 0.05 was considered nominally significant.

We then examined the associations between insomnia trajectories and immune cell subsets ( Additional file 2 : Table S7 ) and identified the overlapping subsets that were nominally significant association with both insomnia trajectories and incident cognitive impairment.

RECCO 23 finds nominally significant recombinants by comparing the cost of obtaining each sequence either by mutation or by recombination.

While linear age adjustment removed several of these spurious findings, a few associations such as mental and behavioral disorders due to opioids, arthrosis, and polyuria remained nominally significant indicating evidence of residual confounding, perhaps due to age.

While ANOVA revealed a main effect and pre-planned comparisons were nominally significant, this was no longer apparent after Bonferroni correction, except for shorter tail length in Flu-DHT-treated males.

A P value of <0.05 was considered nominally significant, and to account for multiple comparisons, we applied the Bonferroni correction, establishing a threshold of <0.00357 (0.05/14) to indicate study-wide significance for each separate analysis.

For the replication analyses of genetic variants previously reported to be suggestively associated with plasma glucagon levels, P values < 0.05 was considered to be nominally significant.

In particular Trikalinos and colleagues analyzed 55 meta-analyses and showed that initial studies poorly predicted the presence or absence of a nominally significant effect reported by the corresponding meta-analysis [ 15 ].

We also carried out rare variant TDTs of intronic and intergenic variants with similar results, finding only nominally significant associations attributable to intergenic, low-frequency variants (MAFs ranging between 0.5 and 1%).

Indeed, only one of the top 5 loci from the overall marginal GWAS showed nominally significant interaction effect, and none passed Bonferroni corrections.

We observed nominally significant enrichment of variants in pancreatic progenitor SE for T2D among lean cases (Z = 2.1).