“nominally significant”

All comparisons where the p -value was less than 0.05 by statistical testing should be regarded as nominally significant.

We additionally calculated empirical p values based on the number of nominally significant associations for each WMN-IC after permuting the WMN-IC scores 10000 times, applying FDR correction ( α < 0.05) for six independent tests.

A two‐sided p value of < 0.05 was considered nominally significant. 3 Results 3.1 Subcutaneous Fat Thickness Subcutaneous fat thickness varied across cadaver specimens and body regions.

Moreover, for both gene expression and protein abundance levels, of the genes significant at 0.1% FDR in a given comparison (osteophytic/low-grade or osteophytic/high-grade), ⩾99.5% show the same direction of change in the other comparison and ⩾90% are at least nominally significant.

Similarly, the regression model for subsidence versus NDI improvement, although nominally significant ( B =−0.827; 95% CI, −1.62 to −0.03; standardized β =−0.256; 95% CI, −0.49 to −0.02), explained minimal variance ( R 2 =0.05) and highlighted marginal clinical relevance.

Different laboratories have reported conflicting results related to the association of developmental dyslexia with DCDC2 , our results, as shown below (Table 5 ), do not indicate a significant association but rather a nominally significant association only.

Any other test results were not adjusted for multiplicity and any p-value ≤0.05 from those testing results was interpreted as nominally significant.

GO terms with a P- value < 0.05 were considered nominally significant ( 37 ).

Among 41 measures analyzed, none showed even nominally significant differences between treatment groups.

Post-MTT, there were no consistent or nominally significant differences between the volixibat and placebo groups in LS mean E max , AUC (0–3) or rAUC (0–3) for insulin or C-peptide; for C-peptide, there was a trend towards lower values in the volixibat groups compared with the placebo group (Table 5 and Additional file 2 : Table S1).

Likewise, nominally significant improvements compared with placebo were seen for DDS and continuous severity of illness, and descriptively better outcomes were achieved in CGI item III.

Of note, among the perturbed genes, of the top ten genes ranked by LoF effects on MCH, seven had nominally significant Perturb-seq effects on HBA1 , and for all seven, the sign of the Perturb-seq β matched what we predicted from γ .

Such a small sample size decreases the statistical power and also reduces the chance of generalizability of any nominally significant statistical finding.[ 22 ] Therefore, to increase the statistical power of individual trials on empagliflozin (by decreasing the standard error of the weighted average effect size), its important to summarize the findings by meta-analysis,[ 23 ] as we have attempted in this paper.

rs4961199 (P = 0.02) was the only SNP showing nominally significant evidence of departure from additivity in our data.

Nominally significant results for Model 3 were further scrutinised in sensitivity analyses, that restricted the cohort to the following categories: First, in pregnancies of European maternal ethnicity, given previously reported differences in SRS scores of potentially cultural origin [ 44 ].

The linear trend became stronger and was nominally significant for GS-PS compared to original-PS for cancer mortality in women.

The list of previously mapped loci was here expanded to include nominally significant loci to facilitate pathway enrichment analysis of target genes.

All statistical tests were two-sided; p < 0.05 was considered nominally significant, though given the small sample sizes and ecological design, all p -values should be interpreted with caution [ 9 , 10 , 11 , 12 ]. 2.4.

Of note, 11 of the nominally significant local genetic correlations showed discordant direction with those of corresponding global correlation that showed statistical significance ( S2 and S3 Tables ).

In addition, we found a nominally significant association between PFOS concentrations and treated thyroid disease in men but not in women.

|LogFC|> 1.5 and P value < 0.05 were used as threshold for nominally significant differential expression. ggplot2 and pheatmap packages were used to draw the volcanic maps and heat maps, respectively.

Finally, nominally significant results were reported as only the control group was tested repeatedly. 5 Conclusions The present study provides preliminary evidence on the effect of nicotine and alcohol during the crucial phase of adolescence on the ratio of glutamatergic and dopaminergic neurons in the VTA of male rats.

When those SNPs were analyzed by the location of cancer, 9 (4.31%) were nominally significant in right colon cancer, 12 (5.74%) in left colon cancer (including rs6687758, an SNP previously associated with CRC in the Basque population) and 12 (5.74%) in rectal cancer.

Nominally significant association results for these same two variants were also seen in sensitivity analyses for the contrast of Active TB to no LTBI, and also Active TB to LTBI (Supplementary Tables S4 and S5), providing support that these variants are associated with increased risk for TB.

Thus, SNPs with nominally significant p-values are presented, and False Discovery Rate (FDR) multiple testing correction was applied [ 23 ].