“nominally significant”

Although the relationship between Word ID and sight-reading ability was nominally significant, the relationship between Passage Comprehension and sight reading remained significant when Word ID was used as a covariate ( r = 0.228, p = 0.012, two-tailed).

Additional support for pathogenicity was sought from a large case-control cohort of MS patients from Europe, and, although most populations present a higher prevalence of PLG p.G420D in MS patients than controls, a nominally significant difference was observed only in the French cohort ( Table 1 ).

A nominally significant interaction between IPI and frontline treatment was observed, which indicates IPI as a prognostic indicator should be taken into consideration in clinical settings.

Similar studies have found a nominally significant association of rs140701 with social anxiety disorder [ 38 ].

Effects of variation in P2RX7 on current depressive symptoms: Main effects and interaction with childhood adversities (CHA) and recent life events (RLE) Our statistical analyses did not identify any SNPs with a nominally significant main effect on current depression (BSI-depression) thus clumps could not be identified.

SNP × Sex Interaction Analysis In logistic regression tests of SNP × Sex interaction ( Table S2 ), 8 markers in ZNF804A yield nominally significant evidence of association including all 4 that were associated in primary analyses (rs17508595, rs13393273, rs7597593 and rs1344706).

For the proportion of patients achieving ≥12% improvement in FEV 1 , none of the pairwise comparisons between any of the GFF MDI doses and GP MDI 36 μg were nominally significant ( Table 2 ).

A nominally significant interaction was found between being in Group 2 and age on mortality, with more benefit in younger patients (Fig. 2 ).

Among the nominally significant taxa, only Haemophilus influenzae , Streptococcus pneumoniae , Moraxella catarrhalis and Moraxella lincolnii were identified; of these, only the first two were significant in either test after false discovery rate (FDR) correction.

An allelic p value of less than 0.05 was considered nominally significant and Bonferroni correction for multiple testing of 17 SNPs was applied to the single-point results of the genetic model analysis of genotype.

Association of the AVPR1A gene with the score for reactive aggression due to external provocation or threat was nominally significant ( P _full = 0.016), but did not reach the corrected significance threshold (Table 2 ).

Evaluation of the influence of mismatched reference allele frequencies on assignment accuracy by means of split samples As noted above, in many cases our observed allele frequencies showed nominally significant differences from population reference frequencies.

Although no differentially methylated CpG sites were identified in relation to HRO after multiple testing correction; several nominally significant CpG sites were identified in genes related to insulin signaling; energy and lipid metabolism.

A p value less than 1.07 × 10 −4 (0.05/468, Bonferroni method) was considered statistically significant, while a p value less than 0.05 was considered nominally significant evidence for a potential causal association [ 42 , 43 ].

However, there was a nominally significant interaction with age for 3P‐MACE in patients not taking metformin ( Figure S3 ; see Supporting Information).

Fatty acid differences were nominally significant but not after multiple-testing correction.

In our previous case-only analysis of an SLE patient cohort largely overlapping with this study, a nominally significant association with LN was shown, notwithstanding multiple testing correction [19] .

(2007) found a nominally significant association between PRL and PRLR tagSNPs and plasma prolactin levels in 95 advanced breast cancer cases.

Analyses conditioning on rs58542926 in TM6SF2 (Supplemental Table S5, http://links.lww.com/HEP/I302 ) revealed that the rs58489806 variant in MAU2 remained nominally significant in the overall discovery and meta-analysis data sets but not in the absence of HCV, and other SNPs in this region were not significant after conditioning.

This approach detected 38 missense or nonsense variants with nominally significant difference in frequency between the groups.

Gene Ontology enrichment analysis To provide information regarding the molecular mechanisms involved in the signatures of local adaptation in psychiatric and behavioral traits, a GO enrichment analysis was conducted based on the PRS results; the variants included in the significant PRS and with nominally significant concordant direction with PRS direction were considered in the enrichment analysis.

They identified a nominally significant interaction between total zinc intake and the SLC30A8 rs11558471 variant on fasting glucose levels.

17 SNPs were nominally significant (p uncorrect <0.05) for the combined TDT and parent TDT test statistic.

For the analysis of the druggable genes, we conducted an exploratory analysis by focussing on genes that were nominally significant in at least one TWAS analysis.

Briefly, the predefined statistical criteria used to identify biomarkers of potential interest included: a fully adjusted, significant (false discovery rate of ≤0.05) prospective association with VTE in the tofacitinib treatment arm(s) or a nominally significant association in conjunction with a fully significant treatment effect (tofacitinib vs TNFi) on the change in biomarker levels in a direction matching the association with VTE risk.