We observed similar associations in the high stable trajectory, although only nominally significant for both 3 months (aOR 1.27, 95% CI 0.99, 1.64) and 6 months breastfeeding (aOR 1.20, 95%CI 0.97, 1.48).
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By calculating FPRP values, the probability that nominally significant variants were truly related to cancer incidence was assessed.
Although valine was not significantly associated ( P REG = 0.78) with CSF Aβ 1–42 pathology in males, in females, it showed a nominally significant negative association with an estimated heterogeneity of I 2 = 49.3%.
The RNA levels of nc886-3p in whole blood presented only nominally significant correlations with its predicted targets (Additional file 2 : Table S6), while the RNA levels of nc886-5p in whole blood correlated with 95 targets at the level of FDR < 0.05 (Additional file 2 : Table S7).
Weight loss maintenance (WLM) is defined as a process of maintaining a nominally significant intentional weight loss accomplished by one’s own efforts (Elfhag & Rössner, 2005 ).
MVMR analysis We conducted MVMR analysis to correct for potential pleiotropic effects among nominally significant thyroid function and MS.
As such, we report and discuss nominally significant findings to inform avenues for future work; replication in larger, independent samples is certainly needed.
All p -values are reported without cross-outcome adjustment; a p -value < 0.05 was considered nominally significant.
developed a PD mendelian randomization research portal that investigated a large number of exposures, finding a nominally significant inverse association between smoking and PD 23 Domenighetti et al. identified an inverse association between smoking initiation and PD that was not explained by reverse causation, confounding, or survival or incidence-prevalence biases. 25 Further supporting the inverse relationship between
In a candidate gene association analysis, PRKCA was reported to be associated with HDLC at a nominally significant level, but was not significant after adjusting for multiple testing [90] .
Moreover, it improved neurological recovery at 72 h, with nominally significant effects at 4 h, 24 h, and 7 days observed only in secondary model.
In 2010, common polymorphisms in several serotonin receptors ( HTR1A , HTR2A , and HTR2C ) were investigated in 87 Caucasian GTS individuals and 311 controls, and only the HTR2C polymorphisms Cys759Thr and Gly697Cys showed a nominally significant association with GTS [ 51 ].
We note that a number of comparisons were not independent, and we focused our interpretation on overall consistent patterns rather than individual nominally significant results.
We considered associations with p < 0.05 as nominally significant.
However, after adjusting for admixture, neither SNP remained nominally significant.
Thirty-one meta-analyses (57%) gave a nominally significant findings based on the random effects model.
Finally, while this study is currently the largest of its type, we had multiple observations that were nominally significant, supporting the need for larger studies and expanded sample sizes.
No significant heterogeneity was observed between the study groups and the three singe-nucleotide polymorphisms (SNPs) are nominally significant in the Danish follow-up.
We screened FAERS data from 2004Q1 to 2024Q3, identified 5523 drugs with available Simplified Molecular-Input Line-Entry System (SMILES) representations, and constructed a signal-enriched dataset of 1676 compounds with nominally significant broad-SCAR associations after excluding predefined therapeutic/supportive confounders.
Two‐tailed P ‐values of <0.05 were designated as nominally significant.
It is important to consider that the nominally significant effects that were found in our non-penalized logistic regression model did not survive FDR corrections (Supplementary Table 2 ).
An allelic P value of less than 0.05 was considered nominally significant.
A nominally significant interaction effect between DI and sex was found in predicting the presence of coronary plaque, particularly stronger in women than in men (see Supplementary material online , Table S3 ).
Associations between CTQ and self-perception measures In the full sample, CTQ total score was significantly correlated with the MAIA “trusting” subscale (ρ = −0.26, p = 0.005), but not any of the other MAIA subscales; moreover, this relationship was stronger, and nominally significant, in patients with SSD ( Table 2 ).
Eleven SNPs from two genes showed nominally significant associations with the risks of ovarian cancer.