“nominally significant”

Nonetheless, in Neupane et al., exploratory analysis of exonic variants of our candidate genes identified three nominally significant loci (single variants in C2CD3 and NALCN , and a region with 39 rare variants in CTNNA2 with a p‐value of 0.05, which the authors did not discuss).

A nominally significant p -value threshold of 0.05 was applied using the inverse variance weighted (IVW) MR method to determine significant associations ( 16 ).

Moreover, nominally significant age-dependent effects were identified, in which carriers of protective ADHD variants (C allele carriers of rs4916723 and rs281324) had smaller increases in the amygdala and caudate volumes.

Similarly, the CCL was available in close proximity (less than 50 m) in 46.5% ( n = 20/43) of the CAC-certified hospitals compared with 30.7% ( n = 31/101) of the non-CAC-certified hospitals, with a nominally significant p value of 0.03782.

However, nominally significant enrichment of common variant associations was observed in genes with high expression specificity for developing GABAergic neuron populations, consistent with our previous analyses of the human ganglionic eminences ( 15 , 52 ).

Genomic location of top SNPs for affective temperament phenotypes Proportion of intronic SNPs was nominally significant in case of all five affective temperament phenotypes, and with the exception of anxious temperament phenotype, in case of the other four temperament phenotypes proportion of noncoding RNA intronic SNPs was also nominally significant (Fig. 3 ).

There was a nominally significant difference noted in direct LDL apoB100 synthesis ( Supplemental Table 3 ).

Nevertheless, our data replicate previous nominally significant findings between ASD PRS and negative emotion recognition tasks ( e . g ., sadness and fear).

For VDS-B, the time effects for the two patient groups are similar, very small, and only nominally significant in the psychotic group, but larger and highly significant for controls.

Analyses used SPSS v.29.0 (IBM SPSS, Armonk, NY) and p ≤ 0.05 was designated as nominally significant for the primary comparisons of HGH change and weight loss.

Nominally significant associations were investigated further by testing the SNP’s association with individual CpG sites.

Single marker-based association of selected SNPs with RA risk Two SNPs, rs1893592 ( UBASH3A ) and rs909685 ( SYNGR1 ), were nominally significant in all three genetic models.

These results indicate that the associations are generally robust, although some nominally significant findings are attenuated after FDR adjustment.

In cellular component (CC) category from SynGO terms, post-synapse ( P = 0.014, Q -value = 0.21) and post-synaptic density, intracellular component ( P = 0.018, Q -value = 0.20) (a subclass of post-synapse), showed a nominally significant association with ASD (Fig.

A wider survey of nAChR gene variants in a case-control study for nicotine dependence found evidence for nominally significant associations in CHRNA7 , CHRNA9 , CHRNA5 and CHRNB3 in young Israeli women [7] .

When the epistasis analysis was corrected for multiple testing corresponding to analysis of 30 SNPs (as performed above), the original number of nominally significant two-SNP interactions was reduced to 70%.

By inference methods we describe below, a p-value can be computed, here p=0.017; although nominally significant, the 95% confidence interval for the effect estimate (95% CI [ 0.19 , 1.94 ] ) is very large.

From the third model, we identified 3 nominally significant PGS-by-GSR interactions, specifically the schizophrenia and depression PGSs, although these interaction effects were not significant after adjusting for multiple testing.

In the ear-leaf Pearson correlation network, ZmSPL19 showed only a limited number of nominally significant correlations with known NUE genes, but these correlations suggested a weak bias toward positive association with assimilation-related genes and negative association with part of the uptake/transport module ( Figure 2 b).

Between the log-rank and dRMST tests, 137 of 150 comparisons (91%) were concordant; log-rank was nominally significant in 5 of 13 cases, while dRMST was significant in 8 of 13.

Some nominally significant results were observed.

All tests were two-sided, and P values less than 0.05 were considered to be nominally significant.

Although a P value of less than 0.05 is usually taken as nominally significant, we were conducting seven separate tests.

40% among nominally significant ones), higher estimation uncertainty (median 3.8-fold higher standard errors), and enrichment for gender-specific cancers with smaller sample sizes.

PRS for MDD were positively associated with AD family history in GS:SFHS; the association was nominally significant at three P -value thresholds, although these did not survive multiple testing correction ( Table 1 ).