“nominally significant”

Females with pADHD had a nominally significant 24% lower risk (non-adjusted p = 0.01) of having an inattentive presentation compared to males with pADHD ( Table 3 ).

In models adjusting for cigarettes-per-day, we confirm the association between rs16969968 and lung cancer (p<10 −20 ) and observe a nominally significant association with COPD (p = 0.01); the other loci are not significantly associated with either lung cancer or COPD after adjusting for rs16969968.

Adjusting for potential cofounding factors (sex, age, smoking, alcohol use, physical activity, total energy intake, education, and population substructure) and using linear regression models, we found that 22 of 30 mQTLs, representing 13 genes, showed nominally significant interaction at p < 0.01 with 12 food groups ( Table S1 ).

Differential expression analysis identified 150 nominally significant genes, of which three were significant at p<0.01 ( Fig 5 ).

No genes remained significant after multiple testing correction; however, nominally significant candidates ( p < 0.01) highlighted pathways related to steroidogenesis and metabolic regulation.

In addition, for FI, the analyses showed multiple significant enrichment peaks in blood in men, whereas those in women were only nominally significant ( P = 0.01) (Supplementary Fig. 3a ).

We analyzed 1196 SNPs in the region (chr11: 78,358,876-79,156,992) and found that 39 SNPs showed nominally significant association with SCZ (p < 0.01, Figure 1 B).

The novel SNPs on 11p15.5 were nominally significant ( P < 0.01), whereas SNPs near FAM13A were not significant ( P > 0.1) (Additional file 1 : Table S6).

Nominally significant differences in ON versus OFF state were found for only one protein (paired permutation test nominal p < 0.01).

To consolidate and summarize the pathway enrichment analysis results from gometh , nominally significant GO terms ( P < 0.01) within the “biological processes” category were further run through the REVIGO tool, which avoids reporting GO terms with greater than 70% in semantic similarity measure [ 79 ].

Nominally significant differences versus placebo were generally observed from week 2 ( P ≤ 0.01) and from week 4 onward ( P < 0.001) for both zasocitinib doses across all domains.

Genes or splicing events that are nominally significant at p < 0.01 for SNP heritability ( cis - h g 2 ) are used for training predictive models (Supplementary Figure 3 ).

The transcriptomic effects of individual NDD genes cluster by cell type: the strongest NDD gene correlations are in mature iGLUTs; that is, all nominally significant ( P < 0.01) log 2 fold change (FC) DEGs are most highly correlated with each other and least correlated with the other cell types, whether relative to all scramble control cells (Fig. 1e(i),(ii) and Supplementary Fig. 7c(ii) ) or to random subsets of scramble control cells (Supplementary Fig. 8a,b ).

4 Some of the strongest correlates of EMT, as found in both breast and lung cancer, are provided in Table 1 ; however, many more genes could be implicated by using less stringent statistical cutoffs than what might be used for fitting within the printed page; out of 12,000 genes represented in both breast and lung datasets, over 4,000 have at least a nominally significant correlation with EMT ( P < 0.01, Pearson’s correlation) in both datasets.

A total of 138 peaks had nominally significant differences in occupancy between genotypes ( P < 0.01).

When examining POAG odds across UA PRS tertiles, no clear associations were observed in either cohort, except for one nominally significant finding in LifeLines after excluding possible cases, where the middle tertile showed higher odds of POAG (OR = 2.21, 95% CI = 1.18–4.13, P = 0.01; Supplementary Table S5 ).

Regarding extraversion, we found nominally significant results for the facets ‘warmth’ (slope index: r S = −0.119, p = 0.010, BF 10 = 2.90), ‘assertiveness’ (slope index: r S = −0.109, p = 0.018, BF 10 = 1.73), ‘activity’ (slope index: r S = −0.114, p = 0.014, BF 10 = 2.14), and ‘positive emotions’ (slope index: r S = −0.116, p = 0.012, BF 10 = 2.43).

While standard differential expression analysis comparing control and treated rats identified 0 genes with adjusted p value < 0.05, a targeted approach focusing on the members of the CP/CPPS-proximal interaction network identified 5 genes with a nominally significant p value < 0.01.

BMI effect on UEC was nominally significant with directional concordance with that in Japanese (β = 4.04 × 10 −3 , P = .010 in IVW analysis). 4.

Variants for which this binomial test was nominally significant (P < 0.01) were deemed to be candidate mosaic variants.

Interestingly, a recent analysis of WES data from the UK Biobank ( 43 ) identified a nominally significant gene-based association ( P = 0.01, sequence kernel association test [SKAT]) for THBS1 rare coding variants and POAG (ICD-10 diagnosis code H40), suggesting that further study of rare THBS1 -coding variants in adult-onset POAG might be of interest.

Silencing involves both daf-16 –dependent and –independent routes Of 35 nominally significant ( P <0.01) transcriptional differences between age-1(mg44) F2 and N2DRM adults, 25 were completely reversed (to within 20% of the N2DRM level, or over-reverted) by mutations inactivating daf-16 ; a further 9 genes showed partial reversion, while two, daf-2 and pmk-2 , did not revert at all.

A number of genes, including PRKG1 , CNTN4 , and PRKCE , contained clusters of nominally significant SNPs (p<0.01): 17 SNPs in PRKG1 , 9 SNPs in CNTN4 , and 5 SNPs in PRKCE (see File S2 ).

Nominally significant SNP-trait associations (p < 0.01) were carried forward to trait-enrichment analyses, as previously described ( 35 ).

Taken together, the balance between type III collagen formation and degradation (C3M/PRO‐C3 ratio) was higher in patients with non‐stricturing, non‐penetrating CD (Montreal B1) compared with HCs (albeit only nominally significant, p = 0.010; Table S2 ).