“nominally significant”

Subtype Analysis In the subtype analysis, no test was significant after Bonferroni correction, but several lab values were nominally significant in both groups.

Regardless of reading performance, subjects with READ1d showed nominally significant lower global efficiency, local efficiency, and clustering coefficient compared to subjects without READ1d, with consistent effect directions across metrics; the nodal analysis revealed a significant effect of READ1d on a network spanning lateral, occipital and frontal cortex.

Moreover, the c.230A>T is a specific polymorphism in East-Asian populations and exhibits nominally significant evidence for positive selection in Northern Chinese populations.

There were several C-type associations from the top lists showing the same direction and nominally significant cis -eQTL effect in multiple tissues ( S9 Fig ).

None of the nominally significant pathways remained significant after correction for multiple testing.

However, by examining the nominally significant genetic locus associated with the metabolite on chromosome 10 (BP 60,794,328-61,050,339), nearby genes and phenotypes associated with those genes were identified (genes included PHYHIPL , TRAF6P1 , LINC00844 , and FAM13C ; phenotypes included DNA methylation, sleep duration, and QT-interval duration in Trypanosoma cruzi seropositivity).

A limitation of our study is that the potential partial mediations did not survive Bonferroni multiple comparison correction, they were only nominally significant.

Overlap of nominally significant differentially methylated CpGs (DMCs) in never-smokers versus placebo with nominally significant DMCs in vitamin C versus placebo identified 9059 candidate “restored CpGs” for association with placental transcript expression and respiratory outcomes.

For 81 of the 97 candidate biomarkers, the Pearson correlations were nominally significant for the change in gene expression and the compound response score.

Results at p uncorrected <0.05 were considered nominally significant and results at p FDR<0.05 were considered statistically significant.

Post-hoc analyses of nominally significant interactions were performed using race-specific analyses stratified by baseline fitness or BMI group, with no further adjustment for fitness or BMI.

We extracted the nominally significant results (FDR< 0.05).

For each measure, we will report p values adjusted for the number of these core analyses, as well as nominally significant p values (to enable comparison with previous studies), effect sizes, and descriptive information on frequency and severity of deficits.

Nominally significant interactions for first event of hospitalisation for heart failure (HHF) and HHF/CV death were observed with baseline use of diuretics, including loop diuretics, with an increased benefit of ertugliflozin vs placebo (Figure).

The large sample size of these studies facilitated these analyses, and the results were either statistically significant or nominally significant.

Our study confirms and extends this report, showing that nominally significant results occur significantly less often than expected, even for low MAF SNPs, resulting in a conservative bias.

Among 379 metabolites, 33 were nominally significant at a P value of less than 0.05 in any of the models (model 1 through model 6 in Fig. 1 ) ( Supplementary Table S2 ).

While many taxa were found nominally significant, only Sutterella at 1 yr was associated with lower BMD (β: −2.329 × 10 −3 ; 95% CI, −3.616 × 10 −3 to −1.043 × 10 −3 , after correction for multiple testing: p .adj = .021) and aBMC (β: −2.46; 95% CI, −3.73 to −1.19, after correction for multiple testing: p .adj = .008) and it independently contributed to 2.5% and 2.8% of the variance in BMD and aBMC, respectively ( Table 2 , Figure 3 ).

The HLA-DPA1/DPB1 SNPs did not show nominally significant associations with neocortical LRP in the CFAS material (Table 2 ).

The p values <.05 were considered nominally significant.

For GIPR rs10423928, we observed a marginally non-significant interaction with olive oil ( p = 0.050) (Table 2 ). We identified a nominally significant interaction between a TCF7L2 variant and coffee consumption (rs12255372: p Interaction = 0.048, Table 2 ).

There were 97 proteins with nominally significant p-values, which we used for further analysis.

The average age at examination (AAE) was slightly higher in controls when compared to BD cases (mean AAE ± SD of 39.1 ± 10.9 years in BD and 40.5 ± 11.9 years in controls, P = 1.16 × 10 −2 ) but this nominally significant difference did not withstand Bonferroni correction for all the clinical variables tested.

However, these results were only nominally significant; therefore, larger sample sizes and/or additional cohorts are needed to confirm this finding.

We also observed a nominally significant association between genetically predicted FT4 and SCZ with the WM method.