“nominally significant”

Second, the nominally significant interaction in the efficacy of vorapaxar with regard to ischemic end points should be regarded as hypothesis generating.

p -values were not subjected to multiple testing correction and, therefore, suggested as nominally significant results (Pawełczyk et al., 2012 ).

After applying Bonferroni correction, the three nominally significant situations (ODF-RK2 using the Global Threshold feature method for AD vs.

This allowed identification of those genes for which the 95% CI did not include 50%, suggestive of a nominally significant imbalance.

Additionally, there was a nominally significant 28% lower risk of mortality with ticagrelor monotherapy.

Furthermore, eleven of these miRNAs were nominally significant in both cohorts, when analyzing the USA cohort and the GER cohort separately, and remained significant in the combined analysis.

i.e., nominally significant associations were observed in a different category in the replication stage.

Notably, the TYROBP causal network reached the FDR significance threshold in females (FDR = 0.014) but was only nominally significant in males.

Notably, large-scale rare variant burden testing ranked RHOT1/ Miro1 among the top nominally significant genes in PD, suggesting a possible role in disease susceptibility 18 .

Our analysis ( Table 5 ) revealed that seven bile acids showed nominally significant associations with this SNP, such that the minor allele was associated with higher plasma levels.

[ 77 ] for rs11135058, rs2288831 and rs6870828), we found a nominally significant association between a haplotype in IL12B and resistance to TB in the SAC population (Figure 1 , Table 3 ).

For secondary outcomes, we considered a Bonferroni-corrected p-value of 0.05/12 = 0.004 for statistical significance, describing p-values between 0.004 and 0.05 as “nominally significant”.

The term of FDR-adjusted P was indicated by “ q ,” and the results were considered as nominally significant when q < 0.10 ( 44 ).

Although nominally significant, these subgroup findings should be interpreted with considerable caution.

never long COVID, showing a nominally significant interaction with sex.

Associations with FDR < 0.05 were considered significant, while those with 0.05 < FDR < 0.20 and P < 0.05 were deemed nominally significant causal [ 31 ].

The AUC for this outcome was nominally significant (AUC 0.54, 95% CI 0.52–0.57), with higher scores predictive of outcome, but only when analyzed as a continuous score (OR 1.13 95% CI 1.04–1.24).

Homer was run separately for all nominally significant peaks that were high in CSNK2B siRNA and high in control siRNA with default parameters.

DNA methylation exhibits dynamic changes over time, with some CpG sites showing nominally significant associations with allergic sensitization at birth that later demonstrate genome-wide significance in mid-childhood. 9 This temporal pattern indicates that fetal methylation profiles may influence allergic susceptibility in childhood, further confirming the enduring impact of epigenetic regulation on the development of atopic diseases.

When the 95 % prediction intervals were calculated, which further indicated between-study heterogeneity, we found that the null value was excluded in only 9 % of the associations, this estimate could be explained by the low percentage of nominally significant meta-analyses.

Associations with p values below 0.05 but above 0.0033, such as BF% with back strength (r = −0.046, p = 0.026) and SMM with push-up performance (r = 0.056, p = 0.006), were considered nominally significant only and were not interpreted as robust associations. 3.4 Results of multiple linear regression analyses Multiple linear regression analyses were conducted to identify independent predictors of key physical performance outcomes ( Table 4 ).

The direct comparisons between the Mozart condition and the soft pop/rock conditions at Phase 2 were nominally significant but did not survive the FDR correction; we therefore do not claim that classical music is superior to soft pop/rock music for SpO 2 .

Of these 8 nominally significant associations, 4 genes were also significant predictors of GMR in the low drinking group (rs2213041, rs534957, rs7830, and rs17293059).

None of the metabolites were common to all inflammatory markers ( Supplementary Figure S2B ), and eight metabolites were nominally significant (FDR < 0.1) for all four markers, mainly including the positive associations of PC (O-34:0, O-32:0, O-36:0) and creatine and the adverse associations of LPE (0:0/18:2), LPC (18:2/0:0, 18:1/0:0), and PC (18:1/18:2).

All polymorphisms included in the present study had at least one nominally significant meta-analysis result in SZGene.