“nominally significant”

In regression analysis, P values ≤ 0.01 were considered nominally significant.

Differences in DNAm at cg02623400 and cg0201172 were only nominally significant when restricted to NUPP controls.

The lead isoQTL ( rs4430311 ) showed a significant, negative association with ENST00000492957, but a nominally significant positive association with AKT3 expression.

For the MR of the relative intake of macronutrients and risk of breast cancer, the putative causal effect would be considered if the P of MR met the Bonferroni correction ( p < 0.0125, set as 0.05/4), and p < 0.05 was considered as nominally significant. 2.6.

Our analysis yielded four nominally significant novel putative risk variants ( GABRB1, GABRB2, GRM1 , and WDFY3 ) using data generated by our study of aging models.

All three endpoints achieved Class IV evidence, suggesting that TAPB confers weak or nominally significant analgesic benefits in the immediate postoperative period.

While no statistically significant differences were observed in full‐field visual evoked potential (VEP) latency between treatment and placebo groups in either intention‐to‐treat or per‐protocol populations, exploratory analysis using multifocal VEP indicated a nominally significant improvement with opicinumab.

An additional fifteen PRS were nominally significant, including four breast cancer-related PRS which were all associated with longer survival with the sequencing index date (Supplementary Table 1).

Nevertheless, the restricted effect size on HF did remain similar to our unrestricted analysis and the association remained nominally significant.

A p-value of less than 0.05 was considered to be a nominally significant result.

Nominally significant replication results consistent with the GWAS were observed for two highly correlated SNPs (r 2 = 1 in HapMap CEU samples) in the BAZ2B (bromodomain adjacent zinc finger domain 2B) locus (rs174230, P = 0.03; rs4665058, P = 0.01).

For 15 of the 17 nominally significant cancer SNPs, the “cancer risk allele” was reported in the literature.

The comparison of variant frequencies between Cohort 1 and 2 identified 34 significant hits, involving variants in 20 genes with nominally significant differences in frequencies across the two cohorts; no variant showed a statistically significant difference in prevalence between the two groups after correction for multiple comparisons.

In H3, we identified 333 site pairs with a nominally significant epistasis statistic; we identified 225 such pairs in H1, 205 such pairs in N1, and 188 such pairs in N2 (see Table 1 , and Table S1 ).

Because the sample size was limited (although still among the largest of such studies in this field), we used a p -value <0.05 as the threshold for nominally significant differential expression. 2.3 Analysis of the characteristics of the bone metabolic microenvironment The bone metabolism-related gene sets were obtained from the GSEA database ( http://www.gsea-msigbd .org/gsea/index.jsp) and were related to bone formation and bone resorption, such as bone remodeling, ossification, and multiple cellular processes of osteoclasts and osteoblasts ( Supplementary Table S1 ).

7d ), and the correlation of Log 2 -Fold-Changes of nominally significant genes was low between different brain regions, and modest between 4 and 12 weeks for the same brain region (Supplementary Fig. 7e ).

A two-sided P value <0.05 was considered as nominally significant.

Florez et al [ 106 ], observed that another index of obesity, waist circumstance, showed a nominally significant interation with both IVS3C>T and IVS4G>T in spite of no interaction between BMI and genotype.

We then reported any associations that survived a false discovery rate correction ( Benjamini and Hochberg, 2000 ) of p < 0.05 as significant, although nominally significant results are reported in the tables.

However, our results showed several nominally significant associations with cognitive scores and PGRS, which warrant replication analyses in independent samples.

Only rs1538372 ( P = 0.014) and rs10399931 ( P = 0.047) had a nominally significant association with asthma, respectively.

Despite the lower statistical power, there was good replication in the South Asian samples (12 SNPs nominally significant, of which 8 remained significant after correction for multiple testing), but slightly less so in Africans (Supplementary Data 3 ).

In total, 83 associations were identified to be associated with AF at the nominally significant level (P SMR < 0.05, P HEIDI > 0.01) ( Supplementary Tab le S5 ).

After further adjustment for Aβ changes, nominally significant negative associations were observed in the Banks STS, caudal middle frontal, entorhinal, fusiform, inferior parietal, inferior temporal, isthmus cingulate, lateral occipital, middle temporal, occipital, precuneus, superior parietal, supramarginal, temporal pole, and frontal regions (Supplementary Tables 2 and Fig. 2 d).

We found two nominally significant associations between the occurrence of ICI-induced hepatitis and HLA alleles associated with autoimmune liver diseases among NSCLC patients.