“nominally significant”

The remaining two variants were nominally significant in our study (Supplementary Data 3 ).

Reduction of DME, based on CST changes from baseline, was better for HD combo than IAI, with nominally significant P values.

We identified several significant or nominally significant brain structural regions influenced by sarcopenia-related traits (Table 2 ), as well as several sarcopenia-related traits influenced by brain outcome regions (Table 3 ).

6 SNPs from RRM2B and UBR5 were added to this list because they are both members of GO:6281 “DNA Repair” (which, although nominally significant in GeM, did not reach q < 0.05 and was therefore not used to create the pathway cluster), both lie within a genome‐wide significant association peak in GeM‐HD, and both have significant gene‐wide p values (see Table S5 of the GeM‐HD article). 6 For each gene, the most significant SNP was selected, along with a small number of proxy SNPs in close LD ( r 2 > 0.8) with the most significant SNP that also showed association in GeM‐HD.

A nominally significant larger effect of the GRS was observed among participants with baseline HbA 1c levels above the median as compared with those with values below the median ( P for interaction = 0.02).

For the recent study of ALM in middle-aged and older UKB participants, all 182 lead SNPs were nominally significant in the present study, and up to 168 (92.3%) were significant at the GWS level.

For CER24:0 and CER22:0/16:0, we saw the same pattern, but associations were only nominally significant.

However, it is also important to note that certain SF-36 outcomes that were nominally significant before multiplicity control, such as the SF-36 MH and SF-36 Vitality MCID, did not remain significant after FDR correction.

In the blinding diabetic retinopathy cases, rs669173 (p = 0.017 in the additive model), and rs7521189 (p = 0.023 in the additive model) were nominally significant, however did not survive correction for multiple testing ( Table 2 ).

After adjustment for effects of age, however, only the correlations with hippocampal volume, inferior parietal and inferior frontal cortical thickness were nominally significant ( Table 4 ).

Based on the one-way ANCOVAs, three nominally significant associations were found with the anxiety scale, and one with the depression scale.

In the mouse model, regression analyses comparing COMBI-db/db and MET-db/db groups revealed 82 nominally significant plasma metabolites (Fig. 2 B and Additional file 1: Table S5).

Nominally significant survival associations at the germline level, combined with SV-expression association and other information such as survival associations at the expression-level can help prioritize genes for further investigation.

To avoid associations due to one single species, when we refer to genes that are nominally significant in the PGLS analysis, we always refer to those that were nominally significant for the P value conservative regressions ( P cons < 0.05).

8 , 14 We report only nominally significant genetic correlations with coronary artery disease and myocardial infarction, suggesting a potential common genetic background with atherosclerotic disease.

Although some of the nominally significant associations fully attenuated after adjusting for education, smoking status, body mass index (BMI), and alcohol consumption (Model 2), all of the associations that were significant after multiple testing in the base model (Bonferroni-corrected P < 0.05) remained significant at P < 0.05.

Of all 40 genes identified here, 17 are nominally significant (20 at the P value threshold of 0.1 used in ref. 21 ) and 11 study-wide significant in ref. 21 .

In females, we still observed a nominally significant signal in the M3 mask, with a 15.2-fold in odds of severe disease in M3-variant carriers (95% CI: 1.51–153.4).

nificance but were in genes of biological interest, most notably NRG1, which merits further investigation into their potential role in depression and antidepressant response.' Also in the Discussion section, the following sentence should not have been included: ‘In particular, our analyses provided nominally significant evidence of association of SNP rs11624702 in MDGA2 with response in the combined ISPC-AMPS-STAR*D meta-analysis.'

Of the OTUs that were significant during the neutral water intervention five were among the OTUs with P-values below the 10 th percentile during the alkaline intervention, two of which were nominally significant.

Tissue-specific expression analysis revealed significant enrichment of associated genes in metabolically active tissues, most prominently in the kidney cortex (P adj -value = 6.30×10−5), with nominally significant enrichment in the gastrointestinal tract (transverse colon, P adj -value = 0.03).

Of these, only one SNP yielded nominally significant p values across more than one pain or HRQoL score.

Only nominally significant P-values were observed for C-C motif chemokine 28 (CCL28), C-C motif chemokine 4 (CCL4), monocyte chemoattractant protein-3 (MCP-3), and vascular endothelial growth factor A (VEGFA).

We found that three SNPs in or near the CCR3 gene achieved nominally significant p values; a SNP rs13084656 , located in the promoter region, achieved a p value of 0.039; another SNP rs2157056 , located downstream of the gene, achieved a p value of 6.27×10 −3 ; a third SNP rs2373156 , located in the intronic region, achieved a p value of 0.050.

In preterm infants, when adjusting for preterm co-exposures and co-morbidities, associations between SES and SES × GA and FA are minimally changed, both in the magnitude of association and distribution of nominally significant voxels.