“nominally significant”

[ 65 ] reported a nominally significant association in a Chinese Han population, whereas the results of Davis et al.

A nominally significant non‐linear association was observed only for the aMED score, with a greater rate of risk reduction beginning around a score of 3.5 ( p non‐linearity = 0.04; Figure S1 in supporting information); each one‐unit increase in the aMED and MIND scores was associated with a 5% and 3% lower risk of dementia in linear trend analyses, respectively.

The study successfully met its primary safety endpoint and demonstrated a 76-77% slower cognitive decline from baseline in the active treatment group compared to the sham group that was nominally significant ( 156 ).

LDSC estimated positive genetic correlations between BIP and intake of fish ( r g = 0.24) and vegetables ( r g = 0.29), as well as between MD and fish intake ( r g = 0.25); however, the results were only nominally significant after correction for multiple testing ( Table S8 ).

Finally, we performed a conditional logistic regression analysis for testing if the effects of the two nominally significant SNPs (rs17213159 and rs1023073) showed independent effects.

However, nominally significant metabolites identified in the present study require follow-up in larger settings with more statistical power for subgroup analysis by tumor stage, tumor site, or BMI. 4.

Results The C allele was found to be more common in case subjects than in control subjects (cases, 0.59; controls, 0.54) corresponding to a nominally significant increase in breast cancer risk to heterozygotes and CC homozygotes (odds ratio 1.51, 95% confidence interval 1.01–2.25) in the dominant inheritance model.

SNP rs9990333 showed a nominally significant association with presence of plaque that was directionally consistent [OR 1.32 (95 % CI 1.03; 1.68)], but this SNP showed inconsistent, nonsignificant effects on other NIMA.

Associations to HLA-DRB1*01∶01 and *07∶01 were reduced, but still nominally significant, whereas the associations detected at the *13∶01 and *04∶01 alleles were non-significant.

were able to identify methylated regions of the H19 and TEAD3 genes in the same dataset, with nominally significant P -value and great beta-value differences when comparing high-exposed subjects with lower-exposed ones [ 41 ].

Median-based and inverse-variance weighted approaches detected nominally significant causal association between periodontitis-linked SNPs and SBP or PP ( Table 1 ).

An alternative and commonly applied strategy for discriminating between real and false disease loci identified through association studies is to replicate nominally significant results in independent datasets, thereby reducing type II error as all significant results are followed up.

A p -value less than 0.05, was considered nominally significant.

In men, with only two twin pairs, none of the gene expressions survived correction for multiple comparisons; however, several genes, including LHX1 , showed nominally significant difference in the comparison between ST vs. unaffected twins (Fig. 2b ).

When the P.FDR exceeds 0.05 but the original p value is below 0.05, it is classified as a nominally significant association.

FADS1 showed the most consistent evidence for divergent regulation between agriculturalists, pastoralists, and hunter-gatherers, with nominally significant divergence for 17 tissue models ( supplementary table 2 , Supplementary Material online ).

In the Gansu cohort, numerically larger estimates were observed for several symptoms, although these associations should be interpreted cautiously because they were nominally significant before multiple-testing correction.

rs1571942 and rs12219125 at PLXDC2 locus showed nominally significant (<0.05) association with SDR in the same direction as previous report, as did rs1801282 in PPARG gene with MDR.

p ‐Values <.05 were regarded as nominally significant. 3.

We observed that activating KRAS-G12V mutation was associated with resistance to platinum and topoisomerase inhibitors and showed a nominally significant correlation with vemurafenib (BRAF inhibitor) ( Figures S3 B and S3C).

In the third step, we performed the same forward selection procedure described in step 1 for the gene sets that remained nominally significant after step 2.

While in Study 2, the Morning start group showed increased activation compared to the Varying start group at a nominally significant level in regions with pain (right precentral gyrus, right supplementary motor area) and sensory processing (bilateral paracentral lobule) functions.

A p value less than 0.05 was considered to be nominally significant.

We further conducted a pathway enrichment analysis of the selected mediators for systolic BP and four nominally significant pathways had biological evidence supporting their potential mediation role between age and systolic BP (Additional file 1 : Table S9).

Smaller whole hippocampus volume was found in BD1 (Cohen's d = −0.22, p = 8.9e−11) but not BD2 ( d = −0.11, nominally significant) compared to HC (Figure 1b ; Table S6a ).