However, the arbaclofen group demonstrated a nominally significant improvement on the Clinical Global Impression–Severity (CGI-S).
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For the two haplotypes associated with antisaccade performance, suggestive evidence was found with visual memory and in addition, haplotype block 4 showed a nominally significant association with reduced sensorimotor gating, measured as P50 ratio.
All three loci were nominally significant in a recent GWAS meta-analysis on MDD [ 71 , 75 ], and a TRD study based on predicted ECT probability [ 16 ], strengthening their relevance (Supplementary Table 16 ).
Among individual CpGs, blood had the highest proportion of CpGs correlated to the brain at nominally significant levels (19.0%), followed by saliva (14.4%) and buccal (9.8%).
Those dietary variables that were nominally significant were included in the multivariable Cox proportional hazard regression models.
Initially, we compared the 29 variants showing nominally significant detection frequency differences between the two platforms with the remaining 83 variants.
A list of all nominally significant SNP-QT associations is provided in Supplementary Table S6 .
Click here for file Additional file 9: Table S4 Detailed results for the 10 most nominally significant interactions.
Nominally significant differences that did not withstand FDR correction are shown in Fig. 1 and should be interpreted cautiously.
Several additional genus–host marker associations, including correlations involving lymphocyte percentage and neutrophil percentage, were nominally significant but did not survive FDR correction and were therefore interpreted as exploratory signals only ( Figure 5C and Supplementary Table S4 ).
Over a (median) 18-year follow-up period (1993–2016), conjugated equine estrogens nominally significant reduce for coronary heart disease, breast cancer, hip fracture, and all-cause mortality.
Finally, multiple nominally significant group and age-by-group alterations were detected for ADHD, CP and Epilepsy ( Supp.
A P -value less than 0.05 was treated as nominally significant.
Many differences in the present report were only nominally significant and did not pass multiple testing corrections, and hence should be interpreted with caution.
Other nominally significant secondary measures should be regarded as exploratory.
(mean=22.6; SD=14.4) pre-treatment to 5.0 (mean=13.0; SD=10.8) at 6 months after the treatment ( P =0.038) and to 5.0 (mean=11.2; SD=9.2) at 12 months after the treatment ( P =0.015). Health-Related Quality-of-Life Test (SF12) The weighted standardized physical scores (PCS-12) showed an improving nominally significant trend across the timepoints T0–T12 ( Figure 4 ).
E40K was also nominally significant for triglycerides in the Mexican American populations even with a very small count of nine heterozygotes carrying the K variant (haplotype H96).
We also observed nominally significant sex‐specific differences in the risk for HF (which is likely due to the downstream effects of CAD diagnosis), which remained nominally significant in the sensitivity analyses using sex‐specific weighted scores.
We have highlighted the nominally significant results obtained given the exploratory nature of our analysis.
Conclusion: Intakes of fiber, whole grain, fruits, and meat showed nominally significant associations with relative abundance of several gut bacterial genera.
In AUD patients, our initial analysis revealed several nominally significant associations (Table 5 ).
Thus, a Benjamini–Hochberg false discovery rate (FDR) ≤ 0.05 was considered significant and FDR ≤ 0.10 was considered nominally significant.
The analysis of Belgian CD trios revealed only nominally significant associations with the major alleles (i.e. allele frequency in controls >50%) of four SNPs, three of which are located in the haplotype block encompassing the region covering the MEFV promoter to intron 2 and its 5′ flanking region (rs182674( A ): p = 0.029; rs224217( G ): p = 0.052; rs224231( G ); p = 0.039; rs6501170( T ): p = 0.016; the risk nucleotides are indicated in brackets) ( Figure 2A , Table S1 ).
In the following sections, we discuss the biological relevance of these three metabolite networks (ME7, ME8, and ME11) that were FDR significant and also associated with MetS z-score in boys as primary findings, followed by a discussion of secondary findings comprising other results that were nominally significant at alpha = 0.05. 3.2.
However, these nominally significant differences did not remain significant after FDR correction.