“nominally significant”

However, it is important to note that these conclusions are not focused on nominally significant features; instead, the LASSO-selected features are considered in their multivariable context, where many taxa or features could be interdependent (due to factors such as microbial cooperation/competition or mediation of the effects of one pathway by another).

EA study, 385 (35%) were nominally significant,65 (5.8%) were corrected significant, and most (89%) of these genes had the same effect direction in the AA cohort.

Here the difference in regulation among responders and non-responders was nominally significant ( p : 0.011).

Of these, 2,039 regions contained at least one CpG site profiled in our dataset and 13.4% (274 regions, containing 406 CpG sites) of these were identified as nominally significant with a positive association with total body nevus count.

All p values reported are nominal, with p < 0.05 considered nominally significant.

Notably, the two other associations were nominally significant, with replication p -values 0.024 and 0.038.

Nominally significant interactions occurred with carbohydrate ingestion and MTNR1B-rs1387153 for fasting glucose.

The experimental drug also tended to worsen pain versus the control in 17/20 pairs, and the difference in pain between experimental and control treatment was nominally significant in 3 cases.

Although nominally significant heterogeneity was observed at 7 loci, the overall extent of heterogeneity appeared limited, particularly given the multi-ancestry framework of the analysis.

We found that regardless of chromatin state, typically 6 to 7% of candidate regulatory elements showed (nominally significant) positively correlated transcription initiation with transcription initiation at the nearest annotated genic promoter (Fig. 3b ).

Several nominally significant ratios would be expected to be found by chance alone, given the number of comparisons carried out in this study, many of which are not independent.

Also, there was a nominally significant group-by-time interaction for the volume of the left amygdala ( p uncorrected ≤0.036).

Interestingly, compared with the reference category (never), indicators of religious involvement yielded mostly positive signs, which became nominally significant for seven categories (less than once a year, about once or twice a year, several times a year, about once a month, 2–3 times a month, nearly every week, every week) in the model without interactions, although all of them were trivial in strength.

The authors freely admitted that they had no prespecified sample size or primary end point, and were inspecting the results as data accumulated and stopped when they achieved a nominally significant difference in pregnancy rate.

Subsequent analysis of DMRs from the placentas for ASD outcome revealed 596 nominally significant genes, of which two ( CYP2E1 and IRS2 ) reached genome-wide significance ( Zhu et al., 2019 ).

Inter-group differences in microstate parameters A one-way ANOVA examining microstate parameters across HC, PDNC, and PDD groups revealed several nominally significant findings.

The logistic regression results were compared with the Ingman database of mtSNP frequencies to remove outlier nominally significant associations due to obvious miscalls with the Affymetrix genotyping platform.

There was a nominally significant interaction between race/ethnic group and increase in walk distance with CABG compared with MED alone.

The 94 SNPs are ranked in increasing order of P -value and nominally significant associations are highlighted in bold.

We further evaluated the significance of the excess of nominally significant variants (with 5% expected) using one-sided binomial tests.

Although nominally significant differences in metabolite levels were observed between the doxorubicin-treated groups, none remained significant after correction for multiple testing, with all false discovery rates (FDR) exceeding 0.05 ( Fig.

None of the nominally significant effects reached a Bonferroni corrected level of 9.01 × 10 − 6 .

We did not observe evidence for association with the NCF1 CN nor with the functional variant in carriers of the most frequent CN ratio (4 pseudogenes : 2 gene copies) despite 97% power to detect nominally significant association with PsA or PsV with c.269G>A/p.Arg90His.

For symmetry, the binomial test yielded a nominally significant result for skewness ( ), though this does not survive Holm-Bonferroni correction.

Correlation Between Human-Signal Sensing Data and MSL This section presents the results of the correlation analyses performed between the two MSL measures (ΔSSQ and FMS) and the extracted features to explore nominally significant associations.