“nominally significant”

A two-sided P value of <0.05 was considered nominally significant.

Associations of Individual SNPs With VTE As shown in Table 4 , only the Leiden mutation (rs6025) and rs2066865 (FGG) were significantly associated with VTE risk and found to be nominally significant for the Roma population, but not for the general population.

Although not achieving P adj ≤0.05, identification of the Th2 pathway ( P = 1.22x10 -3 ; P adj = 0.074; z-score -0.82) and Activation of Th1 and Th2 Pathway ( P = 1.32x10 -3 ; P adj = 0.074) as nominally significant canonical pathways is consistent with prior knowledge of immune responses to leishmaniasis.

Assuming that many of these nominally significant results likely represent false positives, we focus on the eight correlations that emerged in at least 5% of the simulations.

Results Association analysis in sorbs We observed nominally significant associations with disinhibition at the variant rs10232478 located in the 5′ untranslated region and the intronic SNPs rs1834150 and rs782881 (Table 2 ).

In the stage I association study of allergic conjunctivitis, we selected 5 SNP in the TEK gene with nominally significant p-values.

17 The metabolites with fold change ≥1.5 or ≤0.67 and p < 0.05 in t ‐test were considered nominally significant, and the metabolites with false discovery rate (FDR) < 0.05 were considered statistically significant.

While several markers were nominally significant at an alpha level of 0.05 (e.g. miR-155-5p for lung cancer), they were not significant following adjustment for multiple testing.

In accordance with earlier reported diet-CRC association, three metabolites, reflecting fiber and wholegrain, and fruit and vegetable intake, showed nominally significant associations to decreased CRC risk, whereas one alcohol-related metabolite showed a nominally signification association to increased CRC risk.

In a recent genome screen of multiplex sibships with prostate cancer, Suarez et al (2000) found nominally significant linkage at two distal markers approximately 20cM from the putative HPC1 region.

Gene-disease pairs nominally significant (P IVW < 0.05) in Mendelian randomization were considered as potential causal candidates.

In addition, several symptoms were reported as milder for LRRK2 G2019S carriers at FDR < 0.1: excess salivation, fatigue, problems eating, constipation, problems with handwriting, bladder control, and problems dressing (nominally significant) compared to the iPD group at a comparable time after symptom onset (Table 3 ).

The enrichment of nominally significant overlapping genes in both arterial tissues (including the aorta) and whole blood, and their directional consistency with ABI, highlights systemic regulatory mechanisms underlying peripheral arterial health.

a nominally significant excess in at least one spring month (March, April, May), and/or a nominally significant reduction in at least one winter month (November, December or January).

Although a nominally significant reduction in the secondary outcome of hospitalization for heart failure was observed with spironolactone, overall the results of the TOPCAT trial were neutral.

The LS mean change in acute medication use days showed a nominally significant difference from placebo starting at the first treatment period and persisting in the second and third treatment periods (Figure S3).

Case-control association analyses using clinically discordant DZ twins as both cases and controls, while underpowered, identified a large number of nominally significant SNPs associated with genes that are significantly enriched in autism risk genes.

For both conditions, merely 2 out of 48 specifications yielded nominally significant outcomes, which means that evidence for any beneficial effects of KV448 or other music on epilepsy seems doubtful.

Both scores of bone-mineral density (in the femoral neck and in the lumbar spine) are nominally significant, suggesting a protective effect for AMD in individuals having a higher bone-mineral density.

Although each of these associations was nominally significant, neither reached the prespecified Bonferroni-adjusted P value.

As for the Wnt agonist RSPO3, we found nominally significant lower levels in SCZ, and no significant differences in BD compared to HC.

Analyses over the intervention period and the cumulative follow-up identified nominally significant intervention benefits related to breast cancer ( 5 , 6 ), CHD ( 7 ), and diabetes ( 8 ).

Results Eighteen immune cell signatures were found to have nominally significant associations with VTE according to the IVW method.

Two nominally significant negative correlations were observed, both for NRG3 (not different from the 1.1 negative correlation expected by chance in 44 tests, underlined in Table 1 ).

All three meta-analysis two-sided tests (fixed effects, random effects, and weighted Z -score) were all nominally significant in both BD and SCZ groups (Table 1B ).