“nominally significant”

p < 0.05 was considered nominally significant [ 25 ].

Although DQB1*05:02 ( P =6.3×10 −3 ) and DQB1*03:01 ( P =0.04) showed nominally significant associations with IHS-LST, there were no HLA-DQB1 alleles that reached the threshold after correction for multiple comparisons.

Early SES was a nominally significant, independent predictor of antisocial ASB, such that lower SES predicted higher levels of ASB in nonadoptive families only.

The summed R 2 for the correlation coefficients reported in the figures is only 3% and if we remove nominally significant results (as these would likely be discarded if multiple test corrections were actually applied) the R 2 reduces to <1%.

Our results indicate that the individual SNP rs1176744 (Tyr129Ser) was nominally significant and a major haplotype formed by rs1176744, rs3758987, and rs4938056 in HTR3B showed significant association with the FTND score.

SUPPLEMENTARY MATERIALS Supplementary Table 1 Comparison of gait parameters between CU individuals and patients with ADD across all gait tasks Supplementary Table 2 Comparison of demographics based on the presence or absence of SNSB data Supplementary Table 3 FDR-adjusted p -values for nominally significant findings in the primary analyses Supplementary Fig. 1 Comparison of cycle time measured by the Smart-insole and GAITRite.

Although baseline patient demographic and disease characteristics were generally consistent between the geographic cohorts, several nominally significant differences were noted.

The nominally significant association between PMDD and positive mood effect for this sample did not survive Bonferroni correction (Table S2 ).

The input data included nominally significant genes (p ​< ​0.05) for SMYD1 or skNAC KD vs.

36 This variant was associated with a lower abundance of Parabacteroides, 36 a genus that is potentially linked to body weight and inflammation, 37 , 38 and with nominally significant altered abundance of certain carbohydrate-digesting genera, including higher abundance of Blautia, 39 a genus that might play a role in metabolic and inflammatory diseases. 40 As the studied European variant only results in a modest reduction in SI activity, the effect of the Arctic-specific complete LoF variant on microbiome composition could potentially be greater.

Results were reported as beta (β) values with standard errors for continuous outcomes, and odds ratios (ORs) with 95% confidence intervals (CIs) for binary outcomes; p-values below 0.05 were considered nominally significant.

While nominally significant HLA associations have been reported, no study to our knowledge has reported unequivocal statistical significance or the dissection of the complex linkage disequilibrium (LD) relationships in the MHC.

In the primary analysis, the hazard ratio for lung cancer was also nominally significant, and in the sensitivity analysis that censored patients at last contact, the hazard ratio for pancreatic cancer was nominally significant.

Results: Our findings reveal a nominally significant positive genome-wide genetic correlation between CAC and AD, which becomes non-significant after excluding the APOE region.

2015) (p,p′-DDE and T-NONA) was detected; nor did we observe the positive nominally significant association between PCBs and ASD outcome (Lyall et al. 2015) in our analyses parameterizing exposure continuously ( Table 1 ).

Nominally significant baseline factors associated with a higher risk of any-CVD included the secondary versus primary cohort, older age, greater weight and BMI in women but not in men, smoking, longer duration of diabetes, family history of MI and type 2 diabetes, higher blood pressure and pulse, and higher total cholesterol, triglyceride, LDLc, and HbA 1c levels.

Three probes from the ESTHER/KORA study 12 and 1 from the twin study 11 were nominally significant in our study, using a fully adjusted model, in both the discovery and validation cohorts (Table S2 ), but they were no longer significant after FDR adjustment.

The study identified 33 nominally significant loci, of which a subset of 9 loci were defined as being genome wide significant by permutation testing (1 locus in greyhounds, 6 loci in Rottweilers and 2 loci in Irish wolfhounds).

P -values ˂0.05 were considered nominally significant.

In addition to the consumption of red meat and fish, several other nutritional phenotypes were nominally significant, therefore, we used the principal component analysis (PCA) based on food consumption-related phenotypes (fish, red meat, salt, sugar, vegetable intake, and leptin) to investigate differences in food pattern between DLSS and controls (Fig. 2 A).

Given the exploratory nature of this analysis, cell types with raw p < 0.05 were considered as nominally significant. 2.7.2.

While this association was nominally significant in the multiple imputation analysis, the effect size was smaller among females and did not meet the threshold after adjusting for multiple comparisons [β = 0.23, 95% CI (0.01–0.14), q = 0.34].

For the executive function domain, while no signal was observed from the main analysis sample, higher CD14 exhibited a nominally significant positive association in the subsample closer in age to exam 7, indicating higher odds of being clustered into the early decline group as compared to the late decline group (estimated odds ratio as 1.57).

A two-sided P value of <0.05 was considered nominally significant.

Associations of Individual SNPs With VTE As shown in Table 4 , only the Leiden mutation (rs6025) and rs2066865 (FGG) were significantly associated with VTE risk and found to be nominally significant for the Roma population, but not for the general population.