“nominally significant”

However, working memory’s significant association with anorexia nervosa increased after the same adjustment, and it gained a significant association with schizophrenia as well as nominally significant associations bipolar disorder and anxiety.

We found a nominally significant correlation between scores for the nondominant 9HPT and the SDMT and TRAIL‐B scores, but the correlations were weak and should be analyzed in more detail in future studies before the significance of this finding can be assessed.

Including these nominally significant signatures present in controls would provide us some suggestive evidence of detection, though caution should be used for potential false positives brought by multiple comparison.

Because the sample size was limited (although still among the largest of such studies in the field), we used raw p-value < 0.05 as threshold for nominally significant differential expression (supplementary Table 1 ).

In terms of an association with cigarette smoking, SC had a nominally significant inverse association with smoking duration.

Although none of the SNPs in the discovery cohort achieved genome-wide significance, 10 of the 50 SNPs carried forward for replication approached genome-wide significance and were also at least nominally significant in the replication cohort; the replicated SNPs are shown in Table 2 .

In our approach, one surrogate variable showed nominally significant differences between groups and were included in our models.

Briefly, the variant nominally significant at the univariable model was censored in the SKAT-O variant count matrix and included as a covariate in the SKAT-O modeling.

Within the regions of NR3C2 and CDH5 , which are two previously reported putative susceptibility genes for CSC ( 15 , 17 ), rs10519952 in NR3C2 ( P = 0.030) showed nominally significant association with choroidal thickness in our GWAS discovery stage ( SI Appendix , Figs.

In addition, we report additional protective variants at IL23R , and identify an excess of additional nominally significant variants in MUC19 , PTPN22 , and C1orf106 .

Preliminary analysis not including any covariates showed nominally significant associations between IgE to egg ≥0.35 kU/l and IgE to the egg component ovomucoid ≥0.35 kU/l and positive oral egg challenge result (p-values 0.028 and 0.028 respectively).

However, this association was only nominally significant, prompting evaluation of additional patients as well as additional potential genetic loci.

Patients were slightly older, but the difference was only nominally significant for remitted patients.

That said, a pair of adjacent bins in bipolar disorder (10.2 and 10.3) and 2 pairs of adjacent bins in schizophrenia (3.4 and 3.5, 6.5 and 6.6) were implicated by nominally significant GSMA findings.

Two vortioxetine doses were investigated because both 10 mg and 20 mg demonstrated nominally significant improvements in MADRS total score and response rate, and acceptable tolerability, in the secondary analysis of a randomized, placebo-controlled, multinational, 8-week, Phase 2/3 trial of vortioxetine that included Japanese participants with MDD. 16 After the treatment period, study drugs were withdrawn, at which point patients entered a 4-week safety follow-up period for the analysis of outcomes of adverse events.

A shared overlap set of 69 variants were nominally significant and of a concordant direction of effect in both study populations; twelve of these variants had marked risk effects (Table 2 ).

Besides, among the association results from the only published GWAS in ALI [ 27 ], genes involved in neuron differentiation were also overrepresented among the nominally significant hits, including those encoding molecules implicated in neural and vascular functions ( S2 Table ), again being the only process overlapping with the results from the microarray studies in the sepsis animal model.

Motts Mill Virus and Craigies Hill Virus Affected the Expression of Genes Related to Development Of the 454 genes that displayed a logFC of more than 0.5 in response to Craigies Hill virus infection, only 4 were nominally significant (adjusted p -value threshold of 0.001; Figure 2 ).

Pairs of variants showing nominally significant interactions in the LRT were further analyzed with generalized linear models.

The GO term “synapse” was nominally significant only when the KNR L1 gene list from the cocaine population was input (Table 1 A).

31 Indeed, Cystatin C remained the most strongly associated with rDNA CN in a multivariate linear model including all blood biochemistry biomarkers related to renal function simultaneously, regardless of whether they appeared as nominally significant on their own ( Figure S16 A; this occurs both with and without C-Reactive Protein, a well-established marker of inflammation, as a covariate).

Post hoc adjustment for age yielded lower relative HRs with nominally significant results in favor of cinacalcet, as did the analyses that accounted for differential withdrawal of study drug and commercial use of cinacalcet in the placebo arm.

It is a Chi square-based test that assesses whether the observed number of studies with nominally significant results is larger than their expected number.

Following Bonferroni correction, P < 0.0038 was considered to indicate statistical significance, and P values ranging from 0.0038 to 0.05 were considered to indicate a nominally significant association.

for both association pairs remain nominally significant given the respective other transcript versus ‘uni-directional’ triplets where association is directionally independent ( Figure 1 a).