“nominally significant”

Results Maternal double dose of the A allele (rs7993594) exhibited a nominally significant increased risk of HDP (RR = 3.52, 95% CI 1.08, 11.20).

Exploratory cross‐sectional correlations between ROI reactivity and clinical measures revealed several nominally significant associations (supplementary results and Figure S1 ), including relationships between amygdala–hippocampal reactivity and anhedonia in the P > C profile.

We identified several significant or nominally significant brain structural regions influenced by sarcopenia-related traits (Table 2 ), as well as several sarcopenia-related traits influenced by brain outcome regions (Table 3 ).

Network analyst was used to understand the protein-protein interaction network [PMID: 25,950,236} of all nominally significant genes (p.unadj < 0.05).

For genotype–phenotype association analyses, although no SNPs passed Bonferroni threshold, there were some SNPs that were suggestively significant that were eQTLs for RNF24 (neuropathy) and MFSD4B/REV3L (vertigo), with other eQTLs for these genes having a nominally significant association with toxicities.

Reduction of DME, based on CST changes from baseline, was better for HD combo than IAI, with nominally significant P values.

In unadjusted comparisons, FSH, T , and FT3 showed nominally significant differences across profiles, and E2 showed a marginal difference.

The rs2247856 showed nominally significant differences in both genotype and allele frequencies in the APOE ε4 non‐carrier group.

present an analytical framework to evaluate rare and de novo noncoding mutations from the whole genome sequencing of 519 ASD families, unable to demonstrate a rare noncoding variant contribution to ASD risk, but found that the noncoding de novo indels category showed a greater number of nominally significant results than expected. 29 The authors 29 demonstrated that the contribution of de novo noncoding variation is probably modest compared to de novo coding variants.

Second, we reported nominally significant causal associations.

The remaining two variants were nominally significant in our study (Supplementary Data 3 ).

A two-sided p value < 0.05 was considered nominally significant for exploratory purposes.

Nominally significant T-cell subsets were selected as candidate variables for further examination in multiple ordinal and multinomial logistic regression analyses with ordered categories of frailty (0, 1–2, 3) as dependent variable, adjusting for age, sex and multimorbidity.

However, caution should be exercised when interpreting these results, since these nominally significant single SNP and haplotype associations would not survive correction for multiple testing.

EMID2_BL1_ht2 , comprising alleles of nominally significant SNPs, rs6945102 , rs4729697 , rs221 , and rs10435333 , was found to be significantly associated with nasal polyposis in the overall Korean asthma patients even after multiple testing corrections, suggesting that the variant may be a marker for inflammation of the nasal mucosa and paranasal sinuses.

Nominally significant associations were observed between variations in the alpha-2A adrenergic receptor gene ( ADRA2A ) and the Slow-5 band.

Variables with P- values <0.05 and <7 × 10 –4 were deemed nominally significant (important) and statistically significant, respectively.

19 , 27 Multivariable Mendelian Randomization Analysis For exposures with nominally significant associations in both primary and replication analyses, we conducted MVMR analyses to test whether the observed effect was mediated by major fibrogenic factors, including MMP2, MMP9, TIMP1, TIMP2, TGFB1, TGFBR1, TGFBR2, SMAD2, SMAD3, and CTGF.

Ten SNPs were nominally significant in the expected direction across this unselected sample.

Risk alleles located in or near HNF1A , PLEKHF2 , and KCNJ11 showed nominally significant interactions with treatment arms to predict progression to diabetes.

Smaller whole hippocampus volume was found in BD1 (Cohen's d = −0.22, p = 8.9e−11) but not BD2 ( d = −0.11, nominally significant) compared to HC (Figure 1b ; Table S6a ).

We further conducted a pathway enrichment analysis of the selected mediators for systolic BP and four nominally significant pathways had biological evidence supporting their potential mediation role between age and systolic BP (Additional file 1 : Table S9).

As EQ-5D score, Borg dyspnoea score and LPH score came after time to clinical worsening (which did not reach statistical significance) in the hierarchy these analyses can only be considered exploratory and nominally significant.

At LPL on chromosome 8, the minor allele A at rs17091905 increased HDL-C and decreased triglycerides, but the direction of the nominally significant effect on CRP was to increase it.

Although there was a trend for all the qRT-PCR data to confirm the array data, only THRAP3 and TFAM were nominally significant (paired T -test).