“narrowly missed statistical significance”

Although the primary endpoint narrowly missed statistical significance immediately after treatment, iCBIT showed a clear trend toward greater tic reduction measured with YGTSS-TTS compared with the placebo condition.

Although the intraoperative complication rate was numerically lower in the RC group, the difference narrowly missed statistical significance.

Furthermore, our data show lower pyramidal symptom prevalence among the male subjects with the rs1801157 TT genotype when compared with the other genotypes, although the results narrowly missed statistical significance, possibly due to the rarity of this genotype in our sample.

Participants identifying as multiracial had higher odds of insomnia (OR 3.22; 95% CI 1.00–10.34), though this narrowly missed statistical significance.

The medial tibial plateau sagittal length (MTPSL) was slightly greater in the MMPRT group compared with controls, although this difference narrowly missed statistical significance. Traditionally, a shorter sagittal plateau length has been theorized to reduce the tibial articular surface available for meniscal excursion, thereby increasing localized contact stresses on the posterior root during flexion.

The moderating effect seemed bolstered when maternal negative IWMs of the child at both 16 months and at 3 years were high, although the difference in effects narrowly missed statistical significance, ΔB = 0.013, SE = 0.012, 95% CI [−0.002, 0.049].

Similar trends were observed in interaction analyses, where the interaction term between MRA use and guideline period in predicting 6‐month mortality narrowly missed statistical significance ( P for interaction = 0.052).

The phase III trial demonstrated a trend in favour of adding the vaccine (median PFS 19.4 versus 11 months), although this narrowly missed statistical significance.

These results indicate a potential trend toward greater improvements in the intervention group, although the interaction effect at EVA 5 narrowly missed statistical significance. 2.

Although it narrowly missed statistical significance, exploratory analyses revealed potentially meaningful benefits in specific subgroups, particularly women and patients with LVEF at the lower end of the spectrum.

Notably a third trial, KEYNOTE-604, assessing the addition of pembrolizumab to first line carboplatin and etoposide, demonstrated a similar improvement in PFS to the studies of the PD-L1 inhibitors above, but narrowly missed statistical significance for an OS benefit; detailed results of this study have not yet been presented or published.

Not even at the 10 percent level of significance is this indicator a significant driver of economic upgrading in the case of SACU – the REC with the best performance in this indicator – as it narrowly missed statistical significance at the 10 percent level.

The trial narrowly missed statistical significance for its primary endpoint of a composite of total hospitalizations for HF and death from cardiovascular causes ( Solomon et al., 2019 ).

In our study, associations with the derived measure of free testosterone narrowly missed statistical significance.

While caries risk and oral hygiene status showed some influence on caries arrest, they narrowly missed statistical significance after adjusting for other covariables [ Table 5 ].

Despite this higher infection burden, rates of vasopressor use and mechanical ventilation were indistinguishable between sexes in every age stratum; indeed, in the 18–44-year cohort, women’s odds of vasopressor use were numerically lower and narrowly missed statistical significance.

More recently, the CREDENCE study, in which the majority of patients had reduced renal function, showed that canagliflozin narrowly missed statistical significance for reducing CV death even in this at-risk group of patients [ 23 ].

Although the absolute HbA1c change over six months showed a favourable trend in the combination group, it narrowly missed statistical significance.

Most recently, the PARAGON‐HF trial, which compared sacubitril/valsartan to valsartan, narrowly missed statistical significance for the primary endpoint of total heart failure hospitalizations and cardiovascular death. 17 However, the data from PARAGON‐HF suggested that patients with LVEF at or below the pre‐specified median of 57% had a greater treatment benefit than those with higher LVEF, and this finding was confirmed when LVEF was assessed continuously.

Consequently, the total hospital costs were lower in the hybrid group, though the difference narrowly missed statistical significance (EUR 18,170.6 ± 737.1 vs.

The common effect model narrowly missed statistical significance with a p -value of 0.056.

Although this narrowly missed statistical significance, the direction and magnitude were consistent with our BMIp models. 3.3.

The study narrowly missed statistical significance for the primary endpoint of a lesser decline in delayed recall at 6 months.

In fact, the p value (0.052) in this analysis only narrowly missed statistical significance.

93 In a subsample of the National Health and Nutrition Examination Survey III, the prevalence of sarcopenic obesity was 42.9% in men and 18.1% in women, but only women had an increased risk of all-cause mortality with sarcopenic obesity (although this narrowly missed statistical significance if mobility limitations were added to the regression analysis). 94 Possibly associated with the risk of morbidity (but having an inconsistent effect on mortality), sarcopenic obesity has been associated with increased risk of adverse cardiovascular events.