Barely Significant
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“might be significant”

2,436 sentences · 2,436 papers · 8,962 search hits before verification · confirmed specimen

Sighted at

p=0.065p=0.54

Listed by Hankins, posted since

In the literature

The performed analyses might be significant to future design and application of pillared graphene based sensors with high sensitivity and large detecting area. pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no
indicated that abnormal expression of methylation-associated enzymes such as DNMT3A and DNMT3B might be significant diagnostic tools rather than indicators of ITP activity [ 30 ]; Another study suggested an important role for DNMT3B rs2424913 Single-nucleotide polymorphisms (SNPs) in altering methylation phenotype and contributing to the pathogenesis of chronic ITP [ 31 ]; Aberrant methylation-related genes such as CD70 have also been involved in ITP, elevated expression of CD70 might be caused by its hypomethylated promoter region and can facilitate the survival of T and B lymphocytes, promote apoptosis of platelets, and enhance secretion of IFN-γ, finally accelerating the progress of ITP [ 32 ].
Metabolomic analysis of the feces was then performed, on the assumption that being downstream of the genome, transcriptome, and proteome, the metabolome would be the best representation of the microbiota phenotype, and that changes in individual metabolites might be significant even in case of small changes on metabolic fluxes, due to cascade or feedback effects.