“might be significant”

On the other hand, the findings of this study might be significant for the basic school level who used ICT tools with the FL; meanwhile, there was very little study available to inform the decisions of basic educators who might be interested in implementing FL in their classrooms ( Segolsson et al., 2017 ).

There might be significant challenges in determining both the numerator and denominator in estimating AP incidence.

The noticed increase might be significant for uterine carcinogenesis, as it is known that many types of malignant tumors are characterized by the increased expression of enzymes involved in the GSH metabolism [ 53 ].

These results suggest that the inhibitory effect of HPB242 on the activation of astrocytes and microglia might be significant to modulate or halt neuroinflammatory-mediated amyloidogenesis.

Owing to the different types of human activities occurring in buildings (including studying, working, entertainment, and catering), the spatial distributions of CO 2 emissions from different buildings within the same grid might be significant differences.

Obesity and other chronic conditions, like diabetes, might be significant in the pathogenesis of COVID‐19 infection.

However, the combined effect of the miRNA on several target genes which share the same biological pathway might be significant and therefore result in measurable phenotypic consequences 28 .

As many studies have been conducted in the chemical industry, exposure to PAH/other confounders (e.g., smoking) might be significant and could interfere with the results.

Therefore, this “contralateral” response to IHT might be significant in the patient’s overall prognosis and could be of greater importance in pathologies with more diffuse damage.

Additionally, we show generation of upstream and divergently oriented transcripts from the alpha-2 tubulin promoter ( Figure 4 B), indicating that bidirectional promoters might be significant contributors to not only antisense, but also sterile transcripts in the cell in non-coding regions.

Discussion Pachydermia lesions are uncommonly reported in patients with acromegaly, although their prevalence might be significant in this setting, particularly in male patients, as demonstrated in this study.

This had led to speculation either that there might be significant differences in the functional characteristics of melanopsin across species [ 16 ] or, alternatively, that the nature of structure-function relationships for melanopsin was at some level fundamentally different from those of rod and cone opsins [ 16 , 20 , 40 ].

Thus there might be significant advantage in using TP over 2D for EF assessment in everyday clinical routine.

Previous studies have shown that there might be significant differences in demographic, clinical, laboratory profile, and outcomes between male and female patients with AIH [ 3 , 6 ].

In this context, if the surface treatment can be easily applied to customized and/or ready-made abutments, the clinical benefit might be significant.

Additionally, the degree of color variation might be significant at a high mixture level.

Thus, PYY action on the limbic system (including the amygdala) might be significant when considering the modulation of hedonic pathways [ 20 ].

With the growing understanding of the function of telomerase in telomere protection in addition to telomere synthesis ( Cesare et al., 2013 ; Perera et al., 2019 ; Sarthy and Baumann, 2010 ), mechanisms of telomerase regulation shown here, implicating potential crosstalk with telomeres, might be significant.

Therefore, it is important to explore what might be significant predictors of improving HSU behavior.

In this case, the K-S test might be significant even if the scores slightly differ from a normal distribution.

The public health effect of such micro-environmental elements might be significant, assuming that improvements to these elements could lead to an increased walking time per person per week.

Conclusions Assuming the number of viable Mtb organisms released offers a reliable proxy of patient infectiousness, our observations imply that TiBr and interindividual variability in Mtb release might be significant contributors to TB transmission among active cases.

23 They might be significant as a source of creativity. 24 They may be experienced as socially and personally significant, conferring a particular sense of self-identity as a voice hearer and providing a source of meaning. 25 Spiritually significant voices may or may not be significant for any or all of these reasons, but they are distinctive by virtue of the spiritual interpretation that is placed on them or—perhaps more correctly—is an integral part of the experienced voice.

These results suggest that many plants used traditionally to treat diabetes have orally available constituents that inhibit DPP-IV, thereby contributing to their spectrum of actions which in the case of some might be significant [ 24 , 25 ].

The issue of the experimental observation of negative refraction was then raised for these water-based metamaterials 19 , since the energy attenuation might be significant in these metafluids due to the intrinsic absorption in the porous micro-beads, and to the strong resonant scattering by the particles.