“might be significant”

20 , 21 The mental health impact of this pandemic in developing countries might be significant due to limited resources, unintegrated health-care systems, and a lack of skilled health-care providers.

It appears that RELE might be significant in treating other aspects of ASDs, but future researchers should test this notion.

Despite the numerous attempts at measuring transcriptional noise in aged tissues, several challenges remain: (i) there are important differences in between studies with regard to the definition of transcriptional noise and the computational methods used to quantify it; (ii) studies focused mostly on single datasets of different tissues and cell types, while it is well known that both the inter-tissue and the inter-cellular variability might be significant; and (iii) little to no attention was given to the fact that cellular composition of aged organs shows relevant variability as compared to the young ( Nalapareddy et al., 2022 ).

Jia et al measured the peripheral dose from an MV-CBCT system and concluded that the peripheral dose due to MV-CBCT imaging might be significant during the daily application of the MV-CBCT procedure. 15 Perks et al found doses of >1 cGy per scan outside the CBCT imaged volume. 16 Apart from the IGRT dose, some studies reported that low radiation dose was associated with the onset of cataracts, thyroid diseases, azoospermia, loss of ovarian function, and oocyte death. 17–22 Su et al indicated that the population exposed to low-dose-rate environmental radiation throughout their lives were highly at risk of cortical and posterior subcapsular lens opacification.

Sample size: Cohort 2a is very small and since the results are consistently in favor of the SMS-group, these differences might be significant in a larger sample.

So far, it has not been the subject of studies of alcohol addiction either, although this moral value might be significant for maintaining abstinence and then the process of sobering.

84 However, bleeding might still occur 65 and might be significant (eg, if surgical stress is applied); therefore, higher-than-prophylactic levels are recommended in FXIII-deficient patients undergoing surgery. 63 , 85 In pregnancy, more frequent replacements with lower doses have been reported to be successful, 69 which is important, as pregnant women with severe

Although it should be noted that potential confounding variables may come into play, the results do suggest that these factors might be significant [ 83 ].

Although most of the ADRs in the primary care setting are not likely to pose life-threatening condition for patients, the consequences on health-related outcomes might be significant.

But this effect might be significant under certain conditions.

Therefore E protein was chosen as a potential antigenic target for the humoral immune responses, which might be significant for developing better diagnostic and research reagents in the future.

Parameter 4 ‐ Trade loss (bans, embargoes, sanctions) by animal product These might be significant in camels and horse farm activities, as well as in milk and/or meat producing farms for animal product trading, but this has not been assessed formally.

In larger cohorts, this effect might be significant.

Recombination might be additionally favored in the case of AMDV because of the high rate of co-infection in farms, and its role in viral evolution might be significant in these circumstances.

From the experimental results, the design of this paper has achieved a good effect, but this study still has some shortcomings: first, there are few subjects, and there might be significant differences in the data related to urine and stool of different subjects, which makes the test results not general, and it is impossible to identify the urine and stool of most users accurately.

For this reason, organized modulation of c-fos expression might be significant for initiating phenotypic protective changes in the central nervous system of a stroke patient.

However, it’s concerning that overdiagnosis risk might be significant, given that more than 92.4% of patients initially classified as high-risk did not manifest AF.

The role of estrogen receptor-α (ERα) in the course of cancer treatment might be significant due to the effect on cellular proliferation and polarity, yet it remains a topic of debate [ 131 , 133 ].

The following guidelines were followed when evaluating heterogeneity using the I 2 statistic: 0% to 40% might not be significant, 30% to 60% might be moderate heterogeneity, 50% to 90% might be significant heterogeneity, and 75% to 100% could represent considerable heterogeneity ( Higgins et al., 2022 ).

However, patients on hemodialysis or pre-dialysis CKD frequently have indwelling catheters and in these patients, these organisms, which are otherwise considered as cultural contaminants, might be significant pathogens, causing biofilm formation and leading to device-related bloodstream infections.

Second, animal numbers used in this study are small and it might well be that minor differences in stroke volume might be significant if higher animal numbers were used.

? Equinus might be Primary, secondary, or coincident with the development of cavus, and its relation might be significant in connection with etiology and in view of the hypothesis of Rocyn Jones.

This gave some reassurance that duty of care-related issues were not influencing the willingness or ability to provide follow-up data, or that there might be significant under-reporting of the rate of duty of care responses at follow-up (Table 4 ).

This observation further reveals that even for the OX063 labels, interaction with the surroundings might be significant enough to produce a narrow distance distribution.

Given the fact that there might be significant number of short peptides which cannot be labelled by iTRAQ reagent for cell supernatant samples, label-free quantification method supported by PEAKS Q of PEAKS Studio v7.0 was used.