“might be significant”

In addition, an ongoing, long-term extension trial ( NCT01500551 , https://classic.clinicaltrials.gov/ct2/show/NCT01500551?term=01500551&draw=2&rank=1 ) might be significant in observing the long-term safety of tofacitinib in paediatric patients.

However, a CTLA4 -mediated susceptibility effect on the development of T1D might be significant in children and adolescents that do not have susceptible HLA class II alleles.

Also, side effects of medical interventions might be significant (e.g., Warren et al., 2011 ).

Based on the survival analysis, SERPINA1, ITLN1, and REG4 might be significant protective prognostic factors for CRC, because high expression levels of these genes were significantly associated with longer OS times (Figure 4C ).

When pathways share genes due to related functions, the correlations between them might be significant depending on the degree of the overlap.

The c coefficient (ensemble) obtained was 3.7±0.3, which, being far from 1, indicates that there also might be significant passive structural anisotropy along the orthogonal short-axes of the cardiomyocyte.

Since there might be significant differences among some cities, it is impossible to generalize the research results.

One possible explanation for the lack of correlation might be significant tissue heterogeneity in tumors; the parameters were estimated from the whole-tumor regions.

Comparison of the activity and structural features of these compounds, suggests that the stereochemistry at C-7′ might be significant in determining and enhancing biological effects [ 66 ].

In addition to its peroxidase activity, peroxiredoxin 6 also has phospholipase A2 activity that might be significant in the brain, which has a high lipid content [ 9 ].

Although an impact of lateral frontal cortex activation on amygdala activation is assumed, individual testosterone fingerprints might be significant, contributing biomarkers that impact the outcomes of, e.g., brain stimulation.

This might be significant especially for older patients with predominantly increased systolic blood pressure. 3) The efficacy is quantitatively not dependent on the presence of a range of concomitant diseases. 4) High compliance of >98% because of a low incidence of adverse events (0.66%) facilitates long-term adequate control of blood pressure.

As SARS-CoV-2 N protein can enhance TGF-β/Smad3 signaling to cause tubular epithelial cell death and AKI via the G1 cell cycle arrest mechanism, the regulation of TGFB1 might be significant in COVID-19 AKI ( Wang et al., 2022 ).

Therefore, there might be significant differences in QST profiles between those with migraine and chronic back pain.

What's more, Chi-square test was performed to test whether there might be significant differences between the number of inter-hemispheric and the number of intra-hemispheric edges.

Our results verified that important interaction between gemcitabine and WTAP might be significant for the clinical treatment of PC. 3.

However, it appears from Fig 2A, that the difference between the activities of RomYN and RomY full length might be significant? 6.

remote access (hardware solutions would require physical access to the real device which sometimes might bring a real burden on the field teams/technicians), flexibility (hardware systems are not very much flexible as software systems; although some hardware platforms are re-configurable such as FPGAs, they are very costly in that form), scalability (due to hardware limitations, cost, and other production constraints’ hardware solutions are hard to scale), agility (time required to install hardware fixes might be significant). 4.2.

Although we have found some programmes delivering relevant BMHI teaching, the credit weight of specialist BMHI modules is relatively low; nevertheless, we have identified four programmes with the potential to be accredited, which, considering the size of the country, might be significant.

et al., 2017 ), while there might be significant differences due to the content of these metabolites.

Moreover, there might be significant bias related to publication, the retrospective design of the study, and the focus on rare or unusual cases.

58 It is important to note that the current survey sample is relatively large ( N = 557); and because χ 2 is highly sensitive to large sample size, it might be significant; however, it is not a reason in itself to reject any of the models as long as the other indices are within the acceptable cut‐offs criteria. 56 , 58 Full information maximum likelihood with robust standard error estimation was employed.

Additionally, we detected other SNPs that might be significant, but have not been reported previously in the literature ( S3 Table ).

Although these results indicate that Vde peptides are in much higher quantity inside the cells than outside, they also show that their amounts in liquid media are almost inexistent for which their presence in yECM might be significant.

In larger cohorts, this effect might be significant.