“may be significant”

Additionally, TRF cannot account for inter-chromosomal variability in telomere length, which may be significant in certain biological contexts.

Assuming that the signals underlying competing potential thoughts must race each other to a threshold ( 171 ), it may be significant that cortical and thalamic projections do not form strong loops ( 172 ).

Therefore, AQP4 may be significant in the upregulation of LRP1 and in the clearance of A β .

Additionally, the activation of CB2 receptors and the modulation of iNOS/eNOS cardiac equilibrium may be significant mechanisms for mediating the cardioprotective impact of the synthetic cannabinoid agonist, WIN55,212-2, towards ischemia–reperfusion injury in an experimental model of type 2 diabetes [ 46 ].

Therefore, a bioengineered periosteum with stem cell homing ability may be significant for large bone defect repair.

Additionally, if unwanted byproducts are created due to side reactions, there may be significant good manufacturing practice (GMP) concerns.

3.1 , imply that it is likely there may be significant biogeophysical climate implications in the decadal means as the conditions from polynya or non-polynya events accumulate over a winter season.

In addition to desiccation, osmotic stress in the form of salt in the surrounding environment may be significant, e.g., in marine environments.

( 2014 ) noted that inclusive schooling for children with ASD increased opportunities to interact with and learn from typically developing peers, which may be significant for their cognitive development.

It is important to study the role of CSCs in a highly heterogeneous disease such as OC, which may be significant to a better understanding of the oncogenetic and metastatic pathways of the disease and to develop novel strategies against its progression and platinum resistance.

The number of these sub-microscopic cases may be significant, as there is evidence of missing on average half of all P. falciparum infections with microscopy in endemic areas compared with PCR ( 24 ).

Furthermore, since there may be significant inter-individual variation in vital signs and apnea, displaying an acute change compared to an infant's baseline might be the best approach.

The diagnosis of soft tissue TB is usually based on medical history, morphological features, laboratory tests, and histopathological features [ 9 , 11 ], but due to the similarity of these lesions to other skin diseases, the diagnosis may be complex, the diagnosis process may be long, and there may be significant delays.

miR-148a may be significant for the prognosis and targeted therapy of patients with ESCC.

We noticed that if the fish is much smaller than the housing, there may be significant mechanical artifacts that affect the ECG signal quality.

The placebo effect may be significant due to studies that lack sham stimulation and rely solely on subjective sleep measures.

As the expected depth for ONSD measurement is anywhere from 2.4 to 2.9 cm, this divergence may be significant.

Thereafter, there may be significant delays during the diagnostic period, thus so as to not exclude this important time window where survival gains could be made, the study RA obtains each of the dates at first presentation, date of biopsy/cytology and date of histocytological confirmation.

Therefore, they may be significant for clinical research [ 6 , 7 ].

This suggests that there may be significant room for the chromosome to expand and shrink as the cell size varies during the cell cycle.

While our cohort did not cite concerns in the ‘private’ domain, there may be significant bother in this domain and it warrants further evaluation with specific questions directed towards this area.

pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement no pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY Introduction It has been recognized that there may be significant differences in physiologic function of individuals with different craniofacial anatomical relationships ( 1 ).

It is feasible that differences between the groups may be significant if the time periods (e.g., eight hours for evening and eight hours for nighttime) were equal.

CXCR7 or other relevant proteins may contribute to proliferation and may be significant targets for improved cancer therapy.

Considering that FISS is regarded as a chronic inflammation-associated tumor with histological features that are similar to wound healing, the expression of STAT3 may be significant and plays an important role in tumorigenesis.